{"title":"AAV5 Vectors","description":"\u003cp\u003eReady-to-use AAV5 vectors for CNS, astrocyte, and lung gene delivery — low seroprevalence, qPCR-titered and in stock.\u003c\/p\u003e","products":[{"product_id":"aav-null-aav-serotype-5-bhv21500022","title":"AAV-Null (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-Null\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCMV Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500022\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCMV is a strong constitutive viral promoter that drives high-level expression across most cell types; activity can diminish over time in some in vivo settings. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eThe null (empty) transgene contains no functional payload, making this vector ideal as a matched delivery and promoter control.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: Null-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020166291821,"sku":"SL100818-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020166324589,"sku":"SL100818-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500022_aav-null-aav-serotype-5_SL100818.jpg?v=1770796179"},{"product_id":"aav-gfp-aav-serotype-5-bhv21500023","title":"AAV-GFP (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-GFP\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCMV Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500023\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCMV is a strong constitutive viral promoter that drives high-level expression across most cell types; activity can diminish over time in some in vivo settings. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eGFP (green fluorescent protein) is a widely used fluorescent reporter for visualizing transduced cells and confirming expression.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: GFP-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020166357357,"sku":"SL100819-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020166390125,"sku":"SL100819-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500023_aav-gfp-aav-serotype-5_SL100819.png?v=1770796179"},{"product_id":"scaav-gfp-aav-serotype-5-self-complementary-bhv21500024","title":"scAAV-GFP (AAV Serotype 5, Self-complementary)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003escAAV-GFP\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCMV Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500024\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCMV is a strong constitutive viral promoter that drives high-level expression across most cell types; activity can diminish over time in some in vivo settings. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eGFP (green fluorescent protein) is a widely used fluorescent reporter for visualizing transduced cells and confirming expression.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: GFP-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020166422893,"sku":"SL100819-SC-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020166455661,"sku":"SL100819-SC-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500024_scaav-gfp-aav-serotype-5-self-complementary_SL100819-SC.png?v=1770796179"},{"product_id":"aav-cre-aav-serotype-5-bhv21500025","title":"AAV-Cre (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-Cre\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCMV Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500025\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecombinase vectors (Cre, Flp, and variants) enable conditional genome editing through site-specific recombination, supporting intersectional strategies, lineage tracing, and conditional knockouts. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCMV is a strong constitutive viral promoter that drives high-level expression across most cell types; activity can diminish over time in some in vivo settings. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eCre recombinase catalyzes site-specific recombination at loxP sites, enabling activation or deletion of conditional alleles.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCre\/loxP recombination\u003c\/li\u003e\n\u003cli\u003eConditional genetics\u003c\/li\u003e\n\u003cli\u003eLineage tracing\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eConfirm Cre\/recombinase-driver expression in target cells before injection.\u003c\/li\u003e\n\u003cli\u003eAllow sufficient time for recombination to occur (typically 1–3 weeks post-injection with AAV2\/5).\u003c\/li\u003e\n\u003cli\u003eValidate recombination efficiency with a reporter allele before proceeding to experimental readouts.\u003c\/li\u003e\n\u003cli\u003eInclude driver-negative animals as genetic negative controls.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020166488429,"sku":"SL100820-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020166521197,"sku":"SL100820-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500025_aav-cre-aav-serotype-5_SL100820.png?v=1770796180"},{"product_id":"scaav-cre-aav-serotype-5-self-complementary-bhv21500026","title":"scAAV-Cre (AAV Serotype 5, Self-complementary)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003escAAV-Cre\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCMV Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500026\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecombinase vectors (Cre, Flp, and variants) enable conditional genome editing through site-specific recombination, supporting intersectional strategies, lineage tracing, and conditional knockouts. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCMV is a strong constitutive viral promoter that drives high-level expression across most cell types; activity can diminish over time in some in vivo settings. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eCre recombinase catalyzes site-specific recombination at loxP sites, enabling activation or deletion of conditional alleles.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCre\/loxP recombination\u003c\/li\u003e\n\u003cli\u003eConditional genetics\u003c\/li\u003e\n\u003cli\u003eLineage tracing\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eConfirm Cre\/recombinase-driver expression in target cells before injection.\u003c\/li\u003e\n\u003cli\u003eAllow sufficient time for recombination to occur (typically 1–3 weeks post-injection with AAV2\/5).\u003c\/li\u003e\n\u003cli\u003eValidate recombination efficiency with a reporter allele before proceeding to experimental readouts.\u003c\/li\u003e\n\u003cli\u003eInclude driver-negative animals as genetic negative controls.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020166553965,"sku":"SL100820-SC-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020166586733,"sku":"SL100820-SC-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500026_scaav-cre-aav-serotype-5-self-complementary_SL100820-SC.png?v=1770796180"},{"product_id":"aav-cre-gfp-aav-serotype-5-bhv21500027","title":"AAV-Cre-GFP (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-Cre-GFP\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCMV Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500027\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecombinase vectors (Cre, Flp, and variants) enable conditional genome editing through site-specific recombination, supporting intersectional strategies, lineage tracing, and conditional knockouts. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCMV is a strong constitutive viral promoter that drives high-level expression across most cell types; activity can diminish over time in some in vivo settings. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eCre-GFP is the encoded payload for this construct. A \u003cstrong\u003eGFP\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCre\/loxP recombination\u003c\/li\u003e\n\u003cli\u003eConditional genetics\u003c\/li\u003e\n\u003cli\u003eLineage tracing\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eConfirm Cre\/recombinase-driver expression in target cells before injection.\u003c\/li\u003e\n\u003cli\u003eAllow sufficient time for recombination to occur (typically 1–3 weeks post-injection with AAV2\/5).\u003c\/li\u003e\n\u003cli\u003eValidate recombination efficiency with a reporter allele before proceeding to experimental readouts.\u003c\/li\u003e\n\u003cli\u003eInclude driver-negative animals as genetic negative controls.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020166619501,"sku":"SL100821-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020166652269,"sku":"SL100821-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500027_aav-cre-gfp-aav-serotype-5_SL100821.png?v=1770796180"},{"product_id":"aav-u6-shrna-scramble-gfp-aav-serotype-5-bhv21500028","title":"AAV-U6-shRNA(scramble)-GFP (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-U6-shRNA(scramble)-GFP\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eU6 Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500028\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eThis vector encodes a specialized payload for targeted gene modulation, including tools such as RNA interference constructs, genome editors, or other functional effectors. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eU6 is an RNA Pol III promoter used specifically to express short non-coding RNAs such as shRNA; it does not drive protein-coding transgenes. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eThe shRNA payload drives RNA interference to silence target genes at the post-transcriptional level. The sensor\/actuator encoded is \u003cstrong\u003eRNAi (shRNA\/miRNA)\u003c\/strong\u003e. A \u003cstrong\u003eGFP\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eRNA interference\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eValidate knockdown efficiency by qPCR or Western blot at your target timepoint.\u003c\/li\u003e\n\u003cli\u003eConfirm GFP co-expression (if present) to assess transduction efficiency before measuring knockdown.\u003c\/li\u003e\n\u003cli\u003eInclude scramble-shRNA controls injected at the same dose to control for non-specific effects.\u003c\/li\u003e\n\u003cli\u003eMonitor for off-target effects using appropriate transcriptomic or phenotypic readouts.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020166685037,"sku":"SL100822-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020166717805,"sku":"SL100822-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500028_aav-u6-shrna-scramble-gfp-aav-serotype-5_SL100822.png?v=1770796181"},{"product_id":"aav-cag-gfp-aav-serotype-5-bhv21500029","title":"AAV-CAG-GFP (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CAG-GFP\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCAG Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500029\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCAG is a potent hybrid promoter (CMV enhancer + chicken beta-actin core) widely favored for robust, sustained transgene expression across diverse tissues. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eGFP (green fluorescent protein) is a widely used fluorescent reporter for visualizing transduced cells and confirming expression.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: GFP-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020166750573,"sku":"SL100823-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020166783341,"sku":"SL100823-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500029_aav-cag-gfp-aav-serotype-5_SL100823.png?v=1770796181"},{"product_id":"aav-synapsin-gfp-aav-serotype-5-bhv21500030","title":"AAV-Synapsin-GFP (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-Synapsin-GFP\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eSynapsin Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500030\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe Synapsin (hSyn) promoter is a compact neuronal promoter that restricts expression to post-mitotic neurons, making it a standard choice for CNS work. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eGFP (green fluorescent protein) is a widely used fluorescent reporter for visualizing transduced cells and confirming expression.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for expression targeted to post-mitotic neurons.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: GFP-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020166816109,"sku":"SL100824-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020166848877,"sku":"SL100824-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500030_aav-synapsin-gfp-aav-serotype-5_SL100824.png?v=1770796181"},{"product_id":"scaav-synapsin-gfp-aav-serotype-5-self-complementary-bhv21500031","title":"scAAV-Synapsin-GFP (AAV Serotype 5, Self-complementary)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003escAAV-Synapsin-GFP\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eSynapsin Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500031\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe Synapsin (hSyn) promoter is a compact neuronal promoter that restricts expression to post-mitotic neurons, making it a standard choice for CNS work. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eGFP (green fluorescent protein) is a widely used fluorescent reporter for visualizing transduced cells and confirming expression.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for expression targeted to post-mitotic neurons.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: GFP-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020166881645,"sku":"SL100824-SC-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020166914413,"sku":"SL100824-SC-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500031_scaav-synapsin-gfp-aav-serotype-5-self-complementary_SL100824-SC.png?v=1770796182"},{"product_id":"aav-cag-chr2-venus-aav-serotype-5-bhv21500064","title":"AAV-CAG-ChR2-Venus (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CAG-ChR2-Venus\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCAG Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500064\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eOptogenetic vectors encode light-sensitive ion channels or pumps that allow millisecond-precision control of neuronal activity with light, enabling causal interrogation of neural circuits. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCAG is a potent hybrid promoter (CMV enhancer + chicken beta-actin core) widely favored for robust, sustained transgene expression across diverse tissues. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eChR2-Venus is the encoded payload for this construct. The sensor\/actuator encoded is \u003cstrong\u003eChR2\u003c\/strong\u003e. A \u003cstrong\u003eVenus\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eOptogenetics\u003c\/li\u003e\n\u003cli\u003eNeural circuit interrogation\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow adequate time for opsin expression before stimulation (typically 2–4 weeks in vivo for AAV2\/5).\u003c\/li\u003e\n\u003cli\u003eConfirm opsin expression with reporter fluorescence before initiating light delivery.\u003c\/li\u003e\n\u003cli\u003eUse appropriate light parameters (wavelength, power, pulse duration) validated for the specific opsin.\u003c\/li\u003e\n\u003cli\u003eInclude non-light-stimulated and vector-only controls to separate expression effects from optogenetic effects.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020169306477,"sku":"SL100848-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020169339245,"sku":"SL100848-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500064_aav-cag-chr2-venus-aav-serotype-5_SL100848.png?v=1770796193"},{"product_id":"aav-mrfp-aav-serotype-5-bhv21500072","title":"AAV-mRFP (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-mRFP\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCMV Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500072\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCMV is a strong constitutive viral promoter that drives high-level expression across most cell types; activity can diminish over time in some in vivo settings. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003emRFP is the encoded payload for this construct. A \u003cstrong\u003emRFP + RFP\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: mRFP-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020169830765,"sku":"SL100856-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020169863533,"sku":"SL100856-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500072_aav-mrfp-aav-serotype-5_SL100856.png?v=1770796196"},{"product_id":"aav-lacz-aav-serotype-5-bhv21500073","title":"AAV-LacZ (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-LacZ\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCMV Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500073\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eThis vector encodes a specialized payload for targeted gene modulation, including tools such as RNA interference constructs, genome editors, or other functional effectors. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCMV is a strong constitutive viral promoter that drives high-level expression across most cell types; activity can diminish over time in some in vivo settings. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eLacZ is the encoded payload for this construct.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: LacZ-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020169896301,"sku":"SL100857-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020169929069,"sku":"SL100857-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500073_aav-lacz-aav-serotype-5_SL100857.png?v=1770796196"},{"product_id":"aav-cag-chief-tdtomato-aav-serotype-5-bhv21500074","title":"AAV-CAG-ChIEF-tdTOMATO (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CAG-ChIEF-tdTOMATO\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCAG Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500074\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eOptogenetic vectors encode light-sensitive ion channels or pumps that allow millisecond-precision control of neuronal activity with light, enabling causal interrogation of neural circuits. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCAG is a potent hybrid promoter (CMV enhancer + chicken beta-actin core) widely favored for robust, sustained transgene expression across diverse tissues. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eChIEF-tdTOMATO is the encoded payload for this construct. The sensor\/actuator encoded is \u003cstrong\u003eChIEF\u003c\/strong\u003e. A \u003cstrong\u003etdTomato\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eOptogenetics\u003c\/li\u003e\n\u003cli\u003eNeural circuit interrogation\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow adequate time for opsin expression before stimulation (typically 2–4 weeks in vivo for AAV2\/5).\u003c\/li\u003e\n\u003cli\u003eConfirm opsin expression with reporter fluorescence before initiating light delivery.\u003c\/li\u003e\n\u003cli\u003eUse appropriate light parameters (wavelength, power, pulse duration) validated for the specific opsin.\u003c\/li\u003e\n\u003cli\u003eInclude non-light-stimulated and vector-only controls to separate expression effects from optogenetic effects.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020169961837,"sku":"SL100858-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020169994605,"sku":"SL100858-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500074_aav-cag-chief-tdtomato-aav-serotype-5_SL100858.png?v=1770796196"},{"product_id":"aav-synapsin-rfp-aav-serotype-5-bhv21500082","title":"AAV-Synapsin-RFP (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-Synapsin-RFP\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eSynapsin Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500082\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe Synapsin (hSyn) promoter is a compact neuronal promoter that restricts expression to post-mitotic neurons, making it a standard choice for CNS work. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eRFP is the encoded payload for this construct.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for expression targeted to post-mitotic neurons.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: RFP-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020170649965,"sku":"SL100877-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020170682733,"sku":"SL100877-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500082_aav-synapsin-rfp-aav-serotype-5_SL100877.png?v=1770796199"},{"product_id":"aav-u6-mirna-scramble-gfp-aav-serotype-5-bhv21500103","title":"AAV-U6-miRNA(scramble)-GFP (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-U6-miRNA(scramble)-GFP\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eU6 Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500103\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eU6 is an RNA Pol III promoter used specifically to express short non-coding RNAs such as shRNA; it does not drive protein-coding transgenes. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003emiRNA is the encoded payload for this construct. The sensor\/actuator encoded is \u003cstrong\u003eRNAi (shRNA\/miRNA)\u003c\/strong\u003e. A \u003cstrong\u003eGFP\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: miRNA-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020171993453,"sku":"SL100898-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020172026221,"sku":"SL100898-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500103_aav-u6-mirna-scramble-gfp-aav-serotype-5_SL100898.png?v=1770796206"},{"product_id":"aav-cag-cre-aav-serotype-5-bhv21500157","title":"AAV-CAG-Cre (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CAG-Cre\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCAG Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500157\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecombinase vectors (Cre, Flp, and variants) enable conditional genome editing through site-specific recombination, supporting intersectional strategies, lineage tracing, and conditional knockouts. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCAG is a potent hybrid promoter (CMV enhancer + chicken beta-actin core) widely favored for robust, sustained transgene expression across diverse tissues. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eCre recombinase catalyzes site-specific recombination at loxP sites, enabling activation or deletion of conditional alleles.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCre\/loxP recombination\u003c\/li\u003e\n\u003cli\u003eConditional genetics\u003c\/li\u003e\n\u003cli\u003eLineage tracing\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eConfirm Cre\/recombinase-driver expression in target cells before injection.\u003c\/li\u003e\n\u003cli\u003eAllow sufficient time for recombination to occur (typically 1–3 weeks post-injection with AAV2\/5).\u003c\/li\u003e\n\u003cli\u003eValidate recombination efficiency with a reporter allele before proceeding to experimental readouts.\u003c\/li\u003e\n\u003cli\u003eInclude driver-negative animals as genetic negative controls.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020175827309,"sku":"SL101400-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020175860077,"sku":"SL101400-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500157_aav-cag-cre-aav-serotype-5_SL101400.png?v=1770796228"},{"product_id":"aav-cmv-icre-aav-serotype-5-bhv21500179","title":"AAV-CMV-iCre (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CMV-iCre\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCMV Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500179\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecombinase vectors (Cre, Flp, and variants) enable conditional genome editing through site-specific recombination, supporting intersectional strategies, lineage tracing, and conditional knockouts. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCMV is a strong constitutive viral promoter that drives high-level expression across most cell types; activity can diminish over time in some in vivo settings. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eiCre is an improved Cre recombinase with reduced CpG content, designed to minimize immune responses in vivo.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCre\/loxP recombination\u003c\/li\u003e\n\u003cli\u003eConditional genetics\u003c\/li\u003e\n\u003cli\u003eLineage tracing\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eConfirm Cre\/recombinase-driver expression in target cells before injection.\u003c\/li\u003e\n\u003cli\u003eAllow sufficient time for recombination to occur (typically 1–3 weeks post-injection with AAV2\/5).\u003c\/li\u003e\n\u003cli\u003eValidate recombination efficiency with a reporter allele before proceeding to experimental readouts.\u003c\/li\u003e\n\u003cli\u003eInclude driver-negative animals as genetic negative controls.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020177301869,"sku":"SL101435-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020177334637,"sku":"SL101435-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500179_aav-cmv-icre-aav-serotype-5_SL101435.png?v=1770796236"},{"product_id":"aav-syn-icre-aav-serotype-5-bhv21500187","title":"AAV-Syn-iCre (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-Syn-iCre\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eSynapsin Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500187\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecombinase vectors (Cre, Flp, and variants) enable conditional genome editing through site-specific recombination, supporting intersectional strategies, lineage tracing, and conditional knockouts. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe Synapsin (hSyn) promoter is a compact neuronal promoter that restricts expression to post-mitotic neurons, making it a standard choice for CNS work. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eiCre is an improved Cre recombinase with reduced CpG content, designed to minimize immune responses in vivo.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for expression targeted to post-mitotic neurons.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCre\/loxP recombination\u003c\/li\u003e\n\u003cli\u003eConditional genetics\u003c\/li\u003e\n\u003cli\u003eLineage tracing\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eConfirm Cre\/recombinase-driver expression in target cells before injection.\u003c\/li\u003e\n\u003cli\u003eAllow sufficient time for recombination to occur (typically 1–3 weeks post-injection with AAV2\/5).\u003c\/li\u003e\n\u003cli\u003eValidate recombination efficiency with a reporter allele before proceeding to experimental readouts.\u003c\/li\u003e\n\u003cli\u003eInclude driver-negative animals as genetic negative controls.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020177826157,"sku":"SL101443-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020177858925,"sku":"SL101443-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500187_aav-syn-icre-aav-serotype-5_SL101443.png?v=1770796239"},{"product_id":"aav-syn-flpo-aav-serotype-5-bhv21500193","title":"AAV-Syn-FLPo (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-Syn-FLPo\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eSynapsin Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500193\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eThis vector encodes a specialized payload for targeted gene modulation, including tools such as RNA interference constructs, genome editors, or other functional effectors. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe Synapsin (hSyn) promoter is a compact neuronal promoter that restricts expression to post-mitotic neurons, making it a standard choice for CNS work. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eFLPo is a codon-optimized Flp recombinase for FRT-based intersectional strategies.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for expression targeted to post-mitotic neurons.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: FLPo-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020178219373,"sku":"SL101449-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020178252141,"sku":"SL101449-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500193_aav-syn-flpo-aav-serotype-5_SL101449.png?v=1770796241"},{"product_id":"aav-cag-flpo-aav-serotype-5-bhv21500197","title":"AAV-CAG-FLPo (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CAG-FLPo\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCAG Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500197\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eThis vector encodes a specialized payload for targeted gene modulation, including tools such as RNA interference constructs, genome editors, or other functional effectors. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCAG is a potent hybrid promoter (CMV enhancer + chicken beta-actin core) widely favored for robust, sustained transgene expression across diverse tissues. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eFLPo is a codon-optimized Flp recombinase for FRT-based intersectional strategies.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: FLPo-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020178481517,"sku":"SL101453-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020178514285,"sku":"SL101453-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500197_aav-cag-flpo-aav-serotype-5_SL101453.png?v=1770796242"},{"product_id":"aav-cmv-flpo-aav-serotype-5-bhv21500201","title":"AAV-CMV-FLPo (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CMV-FLPo\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCMV Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500201\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eThis vector encodes a specialized payload for targeted gene modulation, including tools such as RNA interference constructs, genome editors, or other functional effectors. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCMV is a strong constitutive viral promoter that drives high-level expression across most cell types; activity can diminish over time in some in vivo settings. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eFLPo is a codon-optimized Flp recombinase for FRT-based intersectional strategies.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: FLPo-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020178743661,"sku":"SL101457-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020178776429,"sku":"SL101457-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500201_aav-cmv-flpo-aav-serotype-5_SL101457.png?v=1770796243"},{"product_id":"aav-cag-gcamp6s-aav-serotype-5-bhv21500217","title":"AAV-CAG-GCaMP6s (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CAG-GCaMP6s\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCAG Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500217\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eGenetically encoded calcium indicators (GECIs) such as GCaMP permit real-time imaging of neuronal activity and calcium dynamics in vivo with single-cell resolution. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCAG is a potent hybrid promoter (CMV enhancer + chicken beta-actin core) widely favored for robust, sustained transgene expression across diverse tissues. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eGCaMP6s is a sensitive genetically encoded calcium indicator for imaging neuronal activity at single-cell resolution. A \u003cstrong\u003eGFP\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCalcium imaging\u003c\/li\u003e\n\u003cli\u003eNeuronal activity recording\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow 2–4 weeks post-injection for stable sensor expression with AAV2\/5 in vivo.\u003c\/li\u003e\n\u003cli\u003eConfirm baseline fluorescence and responsiveness to depolarizing stimuli before experimental sessions.\u003c\/li\u003e\n\u003cli\u003eMinimize photobleaching with low-power excitation and limit imaging duration.\u003c\/li\u003e\n\u003cli\u003eUse functional controls (KCl, field stimulation) to validate sensor responsiveness in your preparation.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020179792237,"sku":"SL101474-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020179825005,"sku":"SL101474-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500217_aav-cag-gcamp6s-aav-serotype-5_SL101474.png?v=1770796249"},{"product_id":"aav-cag-gcamp6m-aav-serotype-5-bhv21500218","title":"AAV-CAG-GCaMP6m (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CAG-GCaMP6m\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCAG Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500218\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eGenetically encoded calcium indicators (GECIs) such as GCaMP permit real-time imaging of neuronal activity and calcium dynamics in vivo with single-cell resolution. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCAG is a potent hybrid promoter (CMV enhancer + chicken beta-actin core) widely favored for robust, sustained transgene expression across diverse tissues. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eGCaMP6m balances speed and sensitivity for calcium imaging of neural populations. A \u003cstrong\u003eGFP\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCalcium imaging\u003c\/li\u003e\n\u003cli\u003eNeuronal activity recording\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow 2–4 weeks post-injection for stable sensor expression with AAV2\/5 in vivo.\u003c\/li\u003e\n\u003cli\u003eConfirm baseline fluorescence and responsiveness to depolarizing stimuli before experimental sessions.\u003c\/li\u003e\n\u003cli\u003eMinimize photobleaching with low-power excitation and limit imaging duration.\u003c\/li\u003e\n\u003cli\u003eUse functional controls (KCl, field stimulation) to validate sensor responsiveness in your preparation.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020179857773,"sku":"SL101475-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020179890541,"sku":"SL101475-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500218_aav-cag-gcamp6m-aav-serotype-5_SL101475.png?v=1770796249"},{"product_id":"aav-cag-gcamp6f-aav-serotype-5-bhv21500219","title":"AAV-CAG-GCaMP6f (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CAG-GCaMP6f\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCAG Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500219\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eGenetically encoded calcium indicators (GECIs) such as GCaMP permit real-time imaging of neuronal activity and calcium dynamics in vivo with single-cell resolution. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCAG is a potent hybrid promoter (CMV enhancer + chicken beta-actin core) widely favored for robust, sustained transgene expression across diverse tissues. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eGCaMP6f is a fast calcium indicator for tracking rapid action potential-linked calcium transients. A \u003cstrong\u003eGFP\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCalcium imaging\u003c\/li\u003e\n\u003cli\u003eNeuronal activity recording\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow 2–4 weeks post-injection for stable sensor expression with AAV2\/5 in vivo.\u003c\/li\u003e\n\u003cli\u003eConfirm baseline fluorescence and responsiveness to depolarizing stimuli before experimental sessions.\u003c\/li\u003e\n\u003cli\u003eMinimize photobleaching with low-power excitation and limit imaging duration.\u003c\/li\u003e\n\u003cli\u003eUse functional controls (KCl, field stimulation) to validate sensor responsiveness in your preparation.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020179923309,"sku":"SL101476-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020179956077,"sku":"SL101476-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500219_aav-cag-gcamp6f-aav-serotype-5_SL101476.png?v=1770796250"},{"product_id":"aav-camkii-gcamp6m-aav-serotype-5-bhv21500220","title":"AAV-CaMKII-GCaMP6m (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CaMKII-GCaMP6m\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCaMKII Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500220\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eGenetically encoded calcium indicators (GECIs) such as GCaMP permit real-time imaging of neuronal activity and calcium dynamics in vivo with single-cell resolution. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCaMKII targets expression to excitatory neurons, particularly in the hippocampus and cortex, for region-specific manipulation of excitatory circuits. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eGCaMP6m balances speed and sensitivity for calcium imaging of neural populations. A \u003cstrong\u003eGFP\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for expression targeted to excitatory neurons.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCalcium imaging\u003c\/li\u003e\n\u003cli\u003eNeuronal activity recording\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow 2–4 weeks post-injection for stable sensor expression with AAV2\/5 in vivo.\u003c\/li\u003e\n\u003cli\u003eConfirm baseline fluorescence and responsiveness to depolarizing stimuli before experimental sessions.\u003c\/li\u003e\n\u003cli\u003eMinimize photobleaching with low-power excitation and limit imaging duration.\u003c\/li\u003e\n\u003cli\u003eUse functional controls (KCl, field stimulation) to validate sensor responsiveness in your preparation.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020179988845,"sku":"SL101477-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020180021613,"sku":"SL101477-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500220_aav-camkii-gcamp6m-aav-serotype-5_SL101477.png?v=1770796250"},{"product_id":"aav-syn-cre-aav-serotype-5-bhv21500239","title":"AAV-Syn-Cre (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-Syn-Cre\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eSynapsin Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500239\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecombinase vectors (Cre, Flp, and variants) enable conditional genome editing through site-specific recombination, supporting intersectional strategies, lineage tracing, and conditional knockouts. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe Synapsin (hSyn) promoter is a compact neuronal promoter that restricts expression to post-mitotic neurons, making it a standard choice for CNS work. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eCre recombinase catalyzes site-specific recombination at loxP sites, enabling activation or deletion of conditional alleles.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for expression targeted to post-mitotic neurons.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCre\/loxP recombination\u003c\/li\u003e\n\u003cli\u003eConditional genetics\u003c\/li\u003e\n\u003cli\u003eLineage tracing\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eConfirm Cre\/recombinase-driver expression in target cells before injection.\u003c\/li\u003e\n\u003cli\u003eAllow sufficient time for recombination to occur (typically 1–3 weeks post-injection with AAV2\/5).\u003c\/li\u003e\n\u003cli\u003eValidate recombination efficiency with a reporter allele before proceeding to experimental readouts.\u003c\/li\u003e\n\u003cli\u003eInclude driver-negative animals as genetic negative controls.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020181266797,"sku":"SL101505-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020181299565,"sku":"SL101505-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500239_aav-syn-cre-aav-serotype-5_SL101505.png?v=1770796257"},{"product_id":"aav-gfap-gfp-aav-serotype-5-bhv21500247","title":"AAV-GFAP-GFP (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-GFAP-GFP\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eGFAP Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500247\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe GFAP promoter targets expression to astrocytes and is commonly used for glia-focused gene delivery in the CNS. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eGFP (green fluorescent protein) is a widely used fluorescent reporter for visualizing transduced cells and confirming expression.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for astrocyte-targeted expression in the CNS.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: GFP-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020181791085,"sku":"SL101519-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020181823853,"sku":"SL101519-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500247_aav-gfap-gfp-aav-serotype-5_SL101519.png?v=1770796259"},{"product_id":"aav-gfap-mcherry-aav-serotype-5-bhv21500248","title":"AAV-GFAP-mCherry (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-GFAP-mCherry\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eGFAP Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500248\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe GFAP promoter targets expression to astrocytes and is commonly used for glia-focused gene delivery in the CNS. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003emCherry is a red fluorescent reporter for cell labeling, tracking, and multi-color imaging experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for astrocyte-targeted expression in the CNS.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: mCherry-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020181856621,"sku":"SL101520-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020181889389,"sku":"SL101520-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500248_aav-gfap-mcherry-aav-serotype-5_SL101520.png?v=1770796259"},{"product_id":"aav-cag-luc-aav-serotype-5-bhv21500259","title":"AAV-CAG-Luc (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CAG-Luc\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCAG Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500259\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eThis vector encodes a specialized payload for targeted gene modulation, including tools such as RNA interference constructs, genome editors, or other functional effectors. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCAG is a potent hybrid promoter (CMV enhancer + chicken beta-actin core) widely favored for robust, sustained transgene expression across diverse tissues. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eLuciferase enables bioluminescence imaging for non-invasive in vivo tracking of transduction and gene expression. A \u003cstrong\u003eLuciferase\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: Luc-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020182577517,"sku":"SL101539-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020182610285,"sku":"SL101539-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500259_aav-cag-luc-aav-serotype-5_SL101539.png?v=1770796264"},{"product_id":"aav-mdlx-mcherry-serotype-5-bhv21500320","title":"AAV-mDLX-mCherry (Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-mDLX-mCherry\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003emDlx Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500320\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe mDlx promoter selectively drives expression in GABAergic interneurons, enabling cell-type-specific access to inhibitory populations. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003emDLX-mCherry is the encoded payload for this construct. A \u003cstrong\u003emCherry\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for expression in GABAergic inhibitory interneurons.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: mDLX-mCherry-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020186870125,"sku":"SL116088-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020186902893,"sku":"SL116088-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500320_aav-mdlx-mcherry-serotype-5_SL116088.png?v=1770796286"},{"product_id":"aav-cmv-mcherry-aav-serotype-5-bhv21500322","title":"AAV-CMV-mCherry (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CMV-mCherry\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCMV Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500322\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCMV is a strong constitutive viral promoter that drives high-level expression across most cell types; activity can diminish over time in some in vivo settings. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003emCherry is a red fluorescent reporter for cell labeling, tracking, and multi-color imaging experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: mCherry-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020187001197,"sku":"SL116090-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020187033965,"sku":"SL116090-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500322_aav-cmv-mcherry-aav-serotype-5_SL116090.png?v=1770796286"},{"product_id":"aav-syn-mcherry-aav-serotype-5-bhv21500327","title":"AAV-Syn-mCherry (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-Syn-mCherry\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eSynapsin Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500327\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe Synapsin (hSyn) promoter is a compact neuronal promoter that restricts expression to post-mitotic neurons, making it a standard choice for CNS work. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003emCherry is a red fluorescent reporter for cell labeling, tracking, and multi-color imaging experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for expression targeted to post-mitotic neurons.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: mCherry-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020187328877,"sku":"SL116104-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020187361645,"sku":"SL116104-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500327_aav-syn-mcherry-aav-serotype-5_SL116104.png?v=1770796288"},{"product_id":"aav-camkii-gfp-aav-serotype-5-bhv21500330","title":"AAV-CaMKII-GFP (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CaMKII-GFP\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eSynapsin Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500330\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe Synapsin (hSyn) promoter is a compact neuronal promoter that restricts expression to post-mitotic neurons, making it a standard choice for CNS work. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eGFP (green fluorescent protein) is a widely used fluorescent reporter for visualizing transduced cells and confirming expression.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for expression targeted to post-mitotic neurons.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: GFP-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020187558253,"sku":"SL116107-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020187591021,"sku":"SL116107-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500330_aav-camkii-gfp-aav-serotype-5_SL116107.png?v=1770796289"},{"product_id":"aav-cag-tdtomato-aav-serotype-5-bhv21500344","title":"AAV-CAG-tdTomato (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CAG-tdTomato\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCAG Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500344\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCAG is a potent hybrid promoter (CMV enhancer + chicken beta-actin core) widely favored for robust, sustained transgene expression across diverse tissues. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003etdTomato is a bright red fluorescent protein with high photostability, used for long-term cell tracking.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: tdTomato-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020189032813,"sku":"SL116142-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020189065581,"sku":"SL116142-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500344_aav-cag-tdtomato-aav-serotype-5_SL116142.png?v=1770796295"},{"product_id":"aav-cmv-luc-aav-serotype-5-bhv21500346","title":"AAV-CMV-Luc (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CMV-Luc\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCMV Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500346\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eThis vector encodes a specialized payload for targeted gene modulation, including tools such as RNA interference constructs, genome editors, or other functional effectors. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCMV is a strong constitutive viral promoter that drives high-level expression across most cell types; activity can diminish over time in some in vivo settings. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eLuciferase enables bioluminescence imaging for non-invasive in vivo tracking of transduction and gene expression. A \u003cstrong\u003eLuciferase\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: Luc-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020189294957,"sku":"SL116147-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020189327725,"sku":"SL116147-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500346_aav-cmv-luc-aav-serotype-5_SL116147.png?v=1770796296"},{"product_id":"aav-cag-zsgreen-aav-serotype-5-bhv21500352","title":"AAV-CAG-ZsGreen (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CAG-ZsGreen\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCAG Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500352\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCAG is a potent hybrid promoter (CMV enhancer + chicken beta-actin core) widely favored for robust, sustained transgene expression across diverse tissues. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eZsGreen is the encoded payload for this construct. A \u003cstrong\u003eGFP\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: ZsGreen-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020189786477,"sku":"SL116167-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020189819245,"sku":"SL116167-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500352_aav-cag-zsgreen-aav-serotype-5_SL116167.png?v=1770796299"},{"product_id":"aav-gfap-tdtomato-aav-serotype-5-bhv21500355","title":"AAV-GFAP-tdTomato (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-GFAP-tdTomato\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eGFAP Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500355\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe GFAP promoter targets expression to astrocytes and is commonly used for glia-focused gene delivery in the CNS. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003etdTomato is a bright red fluorescent protein with high photostability, used for long-term cell tracking.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for astrocyte-targeted expression in the CNS.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: tdTomato-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020190245229,"sku":"SL116173-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020190277997,"sku":"SL116173-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500355_aav-gfap-tdtomato-aav-serotype-5_SL116173.png?v=1770796301"},{"product_id":"aav-empty-capsid-serotype-5-bhv21500362","title":"AAV-Empty-Capsid (Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-Empty-Capsid\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eNot specified Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500362\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe promoter for this construct is not specified; refer to the product datasheet for regulatory element details. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eEmpty-Capsid is the encoded payload for this construct.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for cell-type targeting not specified; verify in your model.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: Empty-Capsid-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 Capsid\/mL \/ 30 uL (Std Pack)","offer_id":53020190835053,"sku":"SL116197-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 Capsid\/mL \/ 10 uL (Trial Pack)","offer_id":53020190867821,"sku":"SL116197-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/AAV5-Empty-Capsid.jpg?v=1779470325"},{"product_id":"aav-cag-nanoluc-t2a-mcherry-serotype-5-bhv21500367","title":"AAV-CAG-nanoLuc-T2A-mCherry (Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CAG-nanoLuc-T2A-mCherry\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCAG Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500367\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eThis vector encodes a specialized payload for targeted gene modulation, including tools such as RNA interference constructs, genome editors, or other functional effectors. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCAG is a potent hybrid promoter (CMV enhancer + chicken beta-actin core) widely favored for robust, sustained transgene expression across diverse tissues. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003enanoLuc-T2A-mCherry is the encoded payload for this construct. A \u003cstrong\u003emCherry\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: nanoLuc-T2A-mCherry-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020191293805,"sku":"SL116218-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020191326573,"sku":"SL116218-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500367_aav-cag-nanoluc-t2a-mcherry-serotype-5_SL116218.png?v=1770796305"},{"product_id":"aav-cag-icre-t2a-gfp-aav-serotype-5-bhv21500381","title":"AAV-CAG-iCre-T2A-GFP (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CAG-iCre-T2A-GFP\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCAG Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500381\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecombinase vectors (Cre, Flp, and variants) enable conditional genome editing through site-specific recombination, supporting intersectional strategies, lineage tracing, and conditional knockouts. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCAG is a potent hybrid promoter (CMV enhancer + chicken beta-actin core) widely favored for robust, sustained transgene expression across diverse tissues. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eiCre-T2A-GFP is the encoded payload for this construct. A \u003cstrong\u003eGFP\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCre\/loxP recombination\u003c\/li\u003e\n\u003cli\u003eConditional genetics\u003c\/li\u003e\n\u003cli\u003eLineage tracing\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eConfirm Cre\/recombinase-driver expression in target cells before injection.\u003c\/li\u003e\n\u003cli\u003eAllow sufficient time for recombination to occur (typically 1–3 weeks post-injection with AAV2\/5).\u003c\/li\u003e\n\u003cli\u003eValidate recombination efficiency with a reporter allele before proceeding to experimental readouts.\u003c\/li\u003e\n\u003cli\u003eInclude driver-negative animals as genetic negative controls.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020192440685,"sku":"SL116275-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020192473453,"sku":"SL116275-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500381_aav-cag-icre-t2a-gfp-aav-serotype-5_SL116275.png?v=1770796310"},{"product_id":"aav-ef1a-mcherry-aav-serotype-5-bhv21500385","title":"AAV-EF1a-mCherry (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-EF1a-mCherry\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eEF1α Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500385\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eEF1α (elongation factor 1-alpha) is a strong, broadly expressed housekeeping promoter that typically maintains activity better than CMV in long-term in vivo studies. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003emCherry is a red fluorescent reporter for cell labeling, tracking, and multi-color imaging experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: mCherry-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020192801133,"sku":"SL116304-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020192833901,"sku":"SL116304-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500385_aav-ef1a-mcherry-aav-serotype-5_SL116304.png?v=1770796311"},{"product_id":"aav-syn-luc-aav-serotype-5-bhv21500395","title":"AAV-Syn-Luc (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-Syn-Luc\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eSynapsin Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500395\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eThis vector encodes a specialized payload for targeted gene modulation, including tools such as RNA interference constructs, genome editors, or other functional effectors. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe Synapsin (hSyn) promoter is a compact neuronal promoter that restricts expression to post-mitotic neurons, making it a standard choice for CNS work. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eLuciferase enables bioluminescence imaging for non-invasive in vivo tracking of transduction and gene expression. A \u003cstrong\u003eLuciferase\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for expression targeted to post-mitotic neurons.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: Luc-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020193620333,"sku":"SL116344-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020193653101,"sku":"SL116344-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500395_aav-syn-luc-aav-serotype-5_SL116344.png?v=1770796315"},{"product_id":"aav-syn-null-aav-serotype-5-bhv21500401","title":"AAV-Syn-NULL (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-Syn-NULL\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eSynapsin Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500401\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe Synapsin (hSyn) promoter is a compact neuronal promoter that restricts expression to post-mitotic neurons, making it a standard choice for CNS work. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eThe null (empty) transgene contains no functional payload, making this vector ideal as a matched delivery and promoter control.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for expression targeted to post-mitotic neurons.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: Null-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020194144621,"sku":"SL116350-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020194177389,"sku":"SL116350-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500401_aav-syn-null-aav-serotype-5_SL116350.png?v=1770796317"},{"product_id":"aav-gfap-null-aav-serotype-5-bhv21500439","title":"AAV-GFAP-NULL (AAV Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-GFAP-NULL\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eGFAP Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500439\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eFluorescent reporter and control vectors are foundational tools for validating delivery, benchmarking expression levels, and serving as inert controls in experimental designs. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eThe GFAP promoter targets expression to astrocytes and is commonly used for glia-focused gene delivery in the CNS. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003eThe null (empty) transgene contains no functional payload, making this vector ideal as a matched delivery and promoter control.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for astrocyte-targeted expression in the CNS.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\n\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\n\u003cli\u003eCell labeling\u003c\/li\u003e\n\u003cli\u003ePromoter testing\u003c\/li\u003e\n\u003cli\u003eTransduction benchmarking\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: Null-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; height: 100%; }\n  .detail-section-large.highlight-large {\n    background: #f8fafc;\n    border-left: 6px solid #14b8a6;\n  }\n  .section-header-large {\n    display: flex;\n    align-items: center;\n    gap: 1.25rem;\n    margin-bottom: 1.5rem;\n    padding-bottom: 1.25rem;\n    border-bottom: 2px solid #f1f5f9;\n  }\n  .section-icon-large {\n    width: 4rem;\n    height: 4rem;\n    border-radius: 12px;\n    display: flex;\n    align-items: center;\n    justify-content: center;\n    flex-shrink: 0;\n  }\n  .section-icon-large svg { width: 2.25rem; height: 2.25rem; color: white; }\n  .bg-blue { background: #3b82f6; }\n  .bg-purple { background: #8b5cf6; }\n  .bg-green { background: #10b981; }\n  .bg-orange { background: #f59e0b; }\n  .bg-teal { background: #14b8a6; }\n  .detail-section-large h3 { font-size: 2.25rem; font-weight: 800; color: #0f172a; margin: 0; }\n  .section-body-large p { font-size: 1.5rem; line-height: 1.6; color: #334155; margin: 0 0 1.5rem 0; }\n  .section-body-large p:last-child { margin-bottom: 0; }\n  .section-body-large strong { color: #0f172a; font-weight: 700; }\n  .feature-grid-large { display: flex; flex-direction: column; gap: 2rem; }\n  .feature-item-large h4 { font-size: 1.75rem; font-weight: 700; color: #0f172a; margin: 0 0 0.75rem 0; }\n  .feature-item-large p { font-size: 1.5rem; line-height: 1.6; color: #475569; margin: 0; }\n  .two-column-large { display: grid; grid-template-columns: 1fr 1fr; gap: 2.5rem; margin-bottom: 2.5rem; }\n  .check-list-large { list-style: none; padding: 0; margin: 0; }\n  .check-list-large li {\n    padding: 1rem 0 1rem 3rem;\n    position: relative;\n    font-size: 1.5rem;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n    line-height: 1.5;\n  }\n  .check-list-large li:last-child { border-bottom: none; }\n  .check-list-large li::before {\n    content: \"✓\";\n    position: absolute;\n    left: 0;\n    color: #10b981;\n    font-weight: 800;\n    font-size: 2rem;\n    top: 0.875rem;\n  }\n  .bullet-list-large { list-style: none; padding: 0; margin: 0; }\n  .bullet-list-large li {\n    padding: 1rem 0 1rem 2.5rem;\n    position: relative;\n    font-size: 1.5rem;\n    line-height: 1.6;\n    color: #334155;\n    border-bottom: 2px solid #f8fafc;\n  }\n  .bullet-list-large li:last-child { border-bottom: none; }\n  .bullet-list-large li::before {\n    content: \"•\";\n    position: absolute;\n    left: 0;\n    color: #f59e0b;\n    font-weight: 900;\n    font-size: 2.5rem;\n    line-height: 1;\n    top: 0.5rem;\n  }\n  @media (max-width: 1024px) { .two-column-large { grid-template-columns: 1fr; } }\n  @media (max-width: 768px) {\n    .product-detail-large { padding: 1.5rem; font-size: 1.25rem; }\n    .hero-title-large { font-size: 2.25rem; }\n    .hero-subtitle-large { font-size: 1.5rem; }\n    .detail-section-large h3 { font-size: 1.875rem; }\n    .section-body-large p, .feature-item-large p,\n    .check-list-large li, .bullet-list-large li { font-size: 1.25rem; }\n    .detail-section-large { padding: 1.75rem; }\n  }\n\n  .hero-sku-large { font-size: 1.1rem; color: #94a3b8; margin: 0.75rem 0 0 0; letter-spacing: 0.05em; font-weight: 500; }\n\u003c\/style\u003e","brand":"Biohippo Inc","offers":[{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 30 uL (Std Pack)","offer_id":53020196766061,"sku":"SL116393-30UL","price":488.0,"currency_code":"USD","in_stock":true},{"title":"AAV2\/5 \/ 1.00E+13 VG\/mL \/ 10 uL (Trial Pack)","offer_id":53020196798829,"sku":"SL116393-10UL","price":168.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/BHV21500439_aav-gfap-null-aav-serotype-5_SL116393.png?v=1770796330"},{"product_id":"aav-cag-nanoluc-t2a-gfp-serotype-5-bhv21500441","title":"AAV-CAG-nanoLuc-T2A-GFP (Serotype 5)","description":"\u003cdiv class=\"product-detail-large\"\u003e\n  \u003cdiv class=\"product-hero-large\"\u003e\n    \u003cdiv class=\"hero-badge-large\"\u003eAAV2\/5 Vector\u003c\/div\u003e\n    \u003ch2 class=\"hero-title-large\"\u003eAAV-CAG-nanoLuc-T2A-GFP\u003c\/h2\u003e\n    \u003cp class=\"hero-subtitle-large\"\u003eCAG Promoter • pAAV (AAV2 ITR) • Broad, efficient CNS transduction across large volumes\u003c\/p\u003e\n    \u003cp class=\"hero-sku-large\"\u003eBHV21500441\u003c\/p\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-blue\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M12 3a9 9 0 1 0 9 9c0-.46-.04-.92-.1-1.36a5.389 5.389 0 0 1-4.4 2.26 5.403 5.403 0 0 1-3.14-9.8c-.44-.06-.9-.1-1.36-.1z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eResearch Background\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eThis vector encodes a specialized payload for targeted gene modulation, including tools such as RNA interference constructs, genome editors, or other functional effectors. \u003cstrong\u003eAAV2\/5 has broad, efficient CNS transduction across large volumes\u003c\/strong\u003e.\u003c\/p\u003e\n      \u003cp\u003eCAG is a potent hybrid promoter (CMV enhancer + chicken beta-actin core) widely favored for robust, sustained transgene expression across diverse tissues. The plasmid backbone is \u003cstrong\u003epAAV (AAV2 ITR)\u003c\/strong\u003e.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003csection class=\"detail-section-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-purple\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M13 10V3L4 14h7v7l9-11h-7z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eWhat This AAV Enables\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cdiv class=\"feature-grid-large\"\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eTransgene Function\u003c\/h4\u003e\n          \u003cp\u003enanoLuc-T2A-GFP is the encoded payload for this construct. A \u003cstrong\u003eGFP\u003c\/strong\u003e reporter tag is co-expressed to facilitate detection and validation of transduction.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eExpression Pattern\u003c\/h4\u003e\n          \u003cp\u003eExpression is \u003cstrong\u003econstitutive\u003c\/strong\u003e—the transgene is continuously driven by the promoter without requiring an external trigger. The promoter is designed for broad, cell-type-agnostic expression across diverse tissue types.\u003c\/p\u003e\n        \u003c\/div\u003e\n        \u003cdiv class=\"feature-item-large\"\u003e\n          \u003ch4\u003eCapsid Tropism\u003c\/h4\u003e\n          \u003cp\u003eAAV2\/5 is one of the most efficient serotypes for broad CNS transduction and is favored for large-scale in vivo experiments.\u003c\/p\u003e\n        \u003c\/div\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\n  \u003cdiv class=\"two-column-large\"\u003e\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-green\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M9 5H7a2 2 0 00-2 2v12a2 2 0 002 2h10a2 2 0 002-2V7a2 2 0 00-2-2h-2M9 5a2 2 0 002 2h2a2 2 0 002-2M9 5a2 2 0 012-2h2a2 2 0 012 2\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eCommon Applications\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"check-list-large\"\u003e\u003cli\u003eIn vivo gene delivery\u003c\/li\u003e\u003c\/ul\u003e\n    \u003c\/section\u003e\n\n    \u003csection class=\"detail-section-large compact\"\u003e\n      \u003cdiv class=\"section-header-large\"\u003e\n        \u003cdiv class=\"section-icon-large bg-orange\"\u003e\n          \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n            \u003cpath d=\"M12 9v2m0 4h.01m-6.938 4h13.856c1.54 0 2.502-1.667 1.732-3L13.732 4c-.77-1.333-2.694-1.333-3.464 0L3.34 16c-.77 1.333.192 3 1.732 3z\"\u003e\u003c\/path\u003e\n          \u003c\/svg\u003e\n        \u003c\/div\u003e\n        \u003ch3\u003eExperimental Considerations\u003c\/h3\u003e\n      \u003c\/div\u003e\n      \u003cul class=\"bullet-list-large\"\u003e\n\u003cli\u003eAllow sufficient expression time for AAV2\/5 in your target tissue (often 2–4 weeks in vivo).\u003c\/li\u003e\n\u003cli\u003eVerify targeting and expression level in a pilot cohort before committing to large study groups.\u003c\/li\u003e\n\u003cli\u003eUse appropriate controls: nanoLuc-T2A-GFP-negative or null-vector matched for serotype and dose.\u003c\/li\u003e\n\u003cli\u003eConfirm expression distribution with immunostaining, in situ hybridization, or imaging as appropriate.\u003c\/li\u003e\n\u003c\/ul\u003e\n    \u003c\/section\u003e\n  \u003c\/div\u003e\n\n  \u003csection class=\"detail-section-large highlight-large\"\u003e\n    \u003cdiv class=\"section-header-large\"\u003e\n      \u003cdiv class=\"section-icon-large bg-teal\"\u003e\n        \u003csvg viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"\u003e\n          \u003cpath d=\"M9 12l2 2 4-4m6 2a9 9 0 11-18 0 9 9 0 0118 0z\"\u003e\u003c\/path\u003e\n        \u003c\/svg\u003e\n      \u003c\/div\u003e\n      \u003ch3\u003eControls and Best Practices\u003c\/h3\u003e\n    \u003c\/div\u003e\n    \u003cdiv class=\"section-body-large\"\u003e\n      \u003cp\u003eRecommended controls include: (1) a null or fluorophore-only matched vector to separate delivery effects from payload effects; (2) tissue-matched positive controls to confirm transduction efficiency at your injection coordinates and timepoint; (3) dose-response characterization if the phenotype is sensitive to expression level; and (4) replication across biological cohorts or preparations to confirm robustness.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/section\u003e\n\u003c\/div\u003e\n\u003cstyle\u003e\n  .product-detail-large {\n    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, sans-serif;\n    color: #1e293b;\n    max-width: 1200px;\n    margin: 0 auto;\n    padding: 2rem;\n    font-size: 1.5rem;\n  }\n  .product-hero-large {\n    text-align: center;\n    padding: 3rem 2rem;\n    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);\n    border-radius: 16px;\n    margin-bottom: 3rem;\n    border: 2px solid #e2e8f0;\n  }\n  .hero-badge-large {\n    display: inline-block;\n    background: #3b82f6;\n    color: white;\n    padding: 0.5rem 1.5rem;\n    border-radius: 30px;\n    font-size: 1.25rem;\n    font-weight: 700;\n    margin-bottom: 1rem;\n  }\n  .hero-title-large {\n    font-size: 3rem;\n    font-weight: 800;\n    color: #0f172a;\n    margin: 0 0 1rem 0;\n  }\n  .hero-subtitle-large {\n    font-size: 1.75rem;\n    color: #64748b;\n    margin: 0;\n    font-weight: 500;\n  }\n  .detail-section-large {\n    background: white;\n    border-radius: 16px;\n    padding: 2.5rem;\n    margin-bottom: 2.5rem;\n    border: 2px solid #e2e8f0;\n  }\n  .detail-section-large.compact { margin-bottom: 0; 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