{"title":"Infectious Disease","description":null,"products":[{"product_id":"anti-v5-tag-mouse-monoclonal-antibody-11d5-bha13715056","title":"Anti-V5 Tag Mouse Monoclonal Antibody (11D5)","description":"\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe V5 epitope tag is derived from a small epitope (Pk) present on the P and V proteins of the paramyxovirus of simian virus 5 (SV5). The V5 tag antibody can be helpful in detecting the recombinant proteins, some of which include transmembrane and secreted proteins fusion protein. This V5-tag antibody is prepared by immunizing synthetic peptide GKPIPNPLLGLDST coupled to KLH.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"50 uL","offer_id":52901282677101,"sku":"ABT2170-50UL","price":81.37,"currency_code":"USD","in_stock":true},{"title":"200 uL","offer_id":52901282709869,"sku":"ABT2170-200UL","price":235.87,"currency_code":"USD","in_stock":true},{"title":"200 uL×5","offer_id":52901282742637,"sku":"ABT2170-200ULX5","price":781.77,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/A02170-if.jpg?v=1769705384"},{"product_id":"agarose-conjugated-anti-v5-tag-mouse-monoclonal-antibody-11d5-bha13715057","title":"Agarose Conjugated Anti-V5 Tag Mouse Monoclonal Antibody (11D5)","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e1 mg of Antibody coupled to 1 mL of packed Agarose, per mL of product contains 1 mL Agarose and 1 mL Storage Buffer\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe V5 epitope tag is derived from a small epitope (Pk) present on the P and V proteins of the paramyxovirus of simian virus 5 (SV5). The V5 tag antibody can be helpful in detecting the recombinant proteins, some of which include transmembrane and secreted proteins fusion protein. This V5-tag antibody is prepared by immunizing synthetic peptide GKPIPNPLLGLDST coupled to KLH.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"1 mL","offer_id":52901282775405,"sku":"ABT2173-1ML","price":287.37,"currency_code":"USD","in_stock":true},{"title":"5 mL","offer_id":52901282808173,"sku":"ABT2173-5ML","price":998.07,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/A02170AGB.png?v=1769705385"},{"product_id":"magnetic-beads-conjugated-anti-v5-tag-mouse-monoclonal-antibody-11d5-bha13715058","title":"Magnetic Beads Conjugated Anti-V5 Tag Mouse Monoclonal Antibody (11D5)","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eOver 1mg of Anti-V5 Tag Mouse Monoclonal Antibody coupled to 1 ml of packed magnetic beads.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe V5 epitope tag is derived from a small epitope (Pk) present on the P and V proteins of the paramyxovirus of simian virus 5 (SV5). The V5 tag antibody can be helpful in detecting the recombinant proteins, some of which include transmembrane and secreted proteins fusion protein. This V5-tag antibody is prepared by immunizing synthetic peptide GKPIPNPLLGLDST coupled to KLH.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"1 mL","offer_id":52901282873709,"sku":"ABT2174-1ML","price":369.77,"currency_code":"USD","in_stock":true},{"title":"5 mL","offer_id":52901282906477,"sku":"ABT2174-5ML","price":998.07,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/A02170MGB.png?v=1769705385"},{"product_id":"human-cxcl10-ip-10-elisa-kit-ez-set-diy-antibody-pairs-bhe21000040","title":"Human CXCL10\/IP-10 ELISA Kit EZ-Set™ (DIY Antibody Pairs)","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e C-X-C motif chemokine 10, 10 kDa interferon gamma-induced protein, Gamma-IP10, IP-10, Small-inducible cytokine B10, CXCL10 (1-73), CXCL10, INP10.\u003c\/p\u003e\u003cp\u003eHuman \u003cstrong\u003eCXCL10\/IP-10\u003c\/strong\u003e (\u003cstrong\u003eCXCL10\u003c\/strong\u003e) is an established target in many assay panels, supporting hypothesis testing across diverse biological systems. This target is frequently investigated in \u003cstrong\u003eMolecular \u0026amp; Cellular Biology\u003c\/strong\u003e research contexts. Cytokines and chemokines act as soluble messengers that coordinate immune cell activation, trafficking, and effector functions. Their concentrations can change rapidly in response to infection, tissue injury, or immune stimulation.\u003c\/p\u003e\u003ch2\u003eBiological function and signaling context\u003c\/h2\u003e\u003cp\u003eIn immune signaling networks, cytokine production is often induced by pattern-recognition pathways and inflammatory transcriptional programs, while feedback regulators can dampen responses to restore homeostasis. Chemokine gradients guide leukocyte migration, influencing which cell populations accumulate at a site and how long they persist.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune activation readout:\u003c\/strong\u003e Shifts in abundance can reflect pathway engagement and cellular activation state.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicroenvironment profiling:\u003c\/strong\u003e Levels can help characterize inflammatory tone in tissues or biofluids.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResponse monitoring:\u003c\/strong\u003e Time-course measurements support interpretation of stimulus, treatment, or infection models.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eDisease and translational relevance\u003c\/h2\u003e\u003cp\u003eMany cytokines and chemokines are reported to associate with inflammatory, autoimmune, infectious, and oncology-related processes. In research settings, interpreting changes benefits from pairing this analyte with complementary markers (e.g., upstream triggers, downstream effectors, and cell-type indicators) and considering matrix effects.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"5 plates\/kit","offer_id":52920802509165,"sku":"EZ0735","price":515.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/EZ0735-human-cxcl10-ez-set-elisa-kit-diy-antibody-pairs_74001ede-257d-425f-9f18-fbc324dab43b.jpg?v=1769077482"},{"product_id":"human-mif-elisa-kit-ez-set-diy-antibody-pairs-bhe21000070","title":"Human MIF ELISA Kit EZ-Set™ (DIY Antibody Pairs)","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Macrophage migration inhibitory factor, MIF, Glycosylation-inhibiting factor, GIF, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase, GLIF.\u003c\/p\u003e\u003cp\u003eHuman \u003cstrong\u003eMIF\u003c\/strong\u003e (\u003cstrong\u003eMIF\u003c\/strong\u003e) is a commonly measured biological analyte that can provide insight into cellular state and tissue physiology. This target is frequently investigated in \u003cstrong\u003eMolecular \u0026amp; Cellular Biology\u003c\/strong\u003e research contexts. As with many protein targets, abundance can be influenced by transcriptional regulation, secretion or shedding, proteolytic processing, and clearance. Quantitative measurement is often used to connect molecular changes with phenotypes such as stress responses, immune activation, differentiation, or tissue remodeling.\u003c\/p\u003e\u003ch2\u003eBiological context and interpretation\u003c\/h2\u003e\u003cp\u003eProtein-level readouts complement nucleic-acid measurements by reflecting post-transcriptional control and protein stability. Depending on the model system, changes may be transient or sustained, and may represent direct pathway engagement or secondary effects. When interpreting results, consider sample matrix effects, timing relative to stimulation or treatment, and whether complexes or modified forms of the analyte may be present.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eComparative quantification:\u003c\/strong\u003e Supports analysis across experimental groups, time points, or dose ranges.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePathway context:\u003c\/strong\u003e Useful as part of a broader marker panel to triangulate biological mechanisms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eModel characterization:\u003c\/strong\u003e Helps profile baseline vs perturbed states in cells, tissues, or biofluids.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated pathways and interacting partners\u003c\/h2\u003e\u003cp\u003eFor many targets, interpretability improves when measured alongside biologically connected markers (e.g., upstream regulators, downstream effectors, and cell-type indicators). Designing panels around a pathway hypothesis can help distinguish primary pathway activation from general stress or inflammation.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"5 plates\/kit","offer_id":52920803524973,"sku":"EZ0813","price":515.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ez0813_18e9a205-a312-460b-a0e7-d4e329defb2f.jpg?v=1769077493"},{"product_id":"human-kit-scfr-cd117-c-kit-picokine-quick-elisa-kit-bhe21000325","title":"Human KIT\/SCFR\/CD117\/C Kit PicoKine® Quick ELISA Kit","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003eHuman \u003cstrong\u003eKIT\/SCFR\/CD117\/C Kit\u003c\/strong\u003e (\u003cstrong\u003eKIT\u003c\/strong\u003e) is a commonly measured biological analyte that can provide insight into cellular state and tissue physiology. This target is frequently investigated in \u003cstrong\u003eInfectious Disease\u003c\/strong\u003e research contexts. This analyte is often discussed in the context of \u003cstrong\u003ecell-surface signaling and cell-state markers\u003c\/strong\u003e. Many receptors and surface markers act as gateways for signaling or as phenotypic indicators of specific cell populations and activation states.\u003c\/p\u003e\u003ch2\u003eBiological context\u003c\/h2\u003e\u003cp\u003eIn experimental systems, protein abundance can reflect regulated expression, secretion, processing, or clearance. Interpreting changes benefits from considering compartment (cell-associated vs soluble), the time scale of regulation, and whether complexes or modified forms contribute to the measured signal.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystems-level readout:\u003c\/strong\u003e Quantification supports comparisons across conditions, time points, and treatment groups.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanistic interpretation:\u003c\/strong\u003e Pairing with upstream regulators and downstream markers helps contextualize changes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiomarker-style profiling:\u003c\/strong\u003e Measuring panels of related analytes can improve interpretability in complex models.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920812241261,"sku":"FEK0835","price":513.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/fek0835_1_493fa43f-f473-4ecf-90cf-c409995bb3de.png?v=1769077621"},{"product_id":"mouse-cd14-elisa-kit-picokine-bhe21000569","title":"Mouse CD14 ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14.\u003c\/p\u003e\u003cp\u003eMouse \u003cstrong\u003eCD14\u003c\/strong\u003e (\u003cstrong\u003eCD14\u003c\/strong\u003e) is widely studied as a molecular readout in experimental models where changes in protein abundance reflect underlying biology. This target is frequently investigated in \u003cstrong\u003eCell Signaling\u003c\/strong\u003e research contexts. This analyte is often discussed in the context of \u003cstrong\u003ecell-surface signaling and cell-state markers\u003c\/strong\u003e. Many receptors and surface markers act as gateways for signaling or as phenotypic indicators of specific cell populations and activation states.\u003c\/p\u003e\u003ch2\u003eBiological context\u003c\/h2\u003e\u003cp\u003eIn experimental systems, protein abundance can reflect regulated expression, secretion, processing, or clearance. Interpreting changes benefits from considering compartment (cell-associated vs soluble), the time scale of regulation, and whether complexes or modified forms contribute to the measured signal.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystems-level readout:\u003c\/strong\u003e Quantification supports comparisons across conditions, time points, and treatment groups.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanistic interpretation:\u003c\/strong\u003e Pairing with upstream regulators and downstream markers helps contextualize changes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiomarker-style profiling:\u003c\/strong\u003e Measuring panels of related analytes can improve interpretability in complex models.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920820760941,"sku":"EK0695","price":513.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek0695.jpg?v=1769077747"},{"product_id":"mouse-cxcl1-gro-alpha-elisa-kit-picokine-bhe21000587","title":"Mouse CXCL1\/Gro Alpha ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e C-X-C motif chemokine, Cxcl1, mCG_1708.\u003c\/p\u003e\u003cp\u003eMouse \u003cstrong\u003eCXCL1\/Gro Alpha\u003c\/strong\u003e (\u003cstrong\u003eCXCL1\u003c\/strong\u003e) is widely studied as a molecular readout in experimental models where changes in protein abundance reflect underlying biology. This target is frequently investigated in \u003cstrong\u003eInfectious Disease\u003c\/strong\u003e research contexts. Cytokines and chemokines act as soluble messengers that coordinate immune cell activation, trafficking, and effector functions. Their concentrations can change rapidly in response to infection, tissue injury, or immune stimulation.\u003c\/p\u003e\u003ch2\u003eBiological function and signaling context\u003c\/h2\u003e\u003cp\u003eIn immune signaling networks, cytokine production is often induced by pattern-recognition pathways and inflammatory transcriptional programs, while feedback regulators can dampen responses to restore homeostasis. Chemokine gradients guide leukocyte migration, influencing which cell populations accumulate at a site and how long they persist.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune activation readout:\u003c\/strong\u003e Shifts in abundance can reflect pathway engagement and cellular activation state.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicroenvironment profiling:\u003c\/strong\u003e Levels can help characterize inflammatory tone in tissues or biofluids.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResponse monitoring:\u003c\/strong\u003e Time-course measurements support interpretation of stimulus, treatment, or infection models.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eDisease and translational relevance\u003c\/h2\u003e\u003cp\u003eMany cytokines and chemokines are reported to associate with inflammatory, autoimmune, infectious, and oncology-related processes. In research settings, interpreting changes benefits from pairing this analyte with complementary markers (e.g., upstream triggers, downstream effectors, and cell-type indicators) and considering matrix effects.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920821383533,"sku":"EK0723","price":513.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek0723_3139eae6-4d53-4233-b809-3d6c09124cad.png?v=1769077756"},{"product_id":"human-cxcl10-ip-10-elisa-kit-picokine-bhe21000593","title":"Human CXCL10\/IP-10 ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e C-X-C motif chemokine 10, 10 kDa interferon gamma-induced protein, Gamma-IP10, IP-10, Small-inducible cytokine B10, CXCL10 (1-73), CXCL10, INP10.\u003c\/p\u003e\u003cp\u003eHuman \u003cstrong\u003eCXCL10\/IP-10\u003c\/strong\u003e (\u003cstrong\u003eCXCL10\u003c\/strong\u003e) is an established target in many assay panels, supporting hypothesis testing across diverse biological systems. This target is frequently investigated in \u003cstrong\u003eMolecular \u0026amp; Cellular Biology\u003c\/strong\u003e research contexts. Cytokines and chemokines act as soluble messengers that coordinate immune cell activation, trafficking, and effector functions. Their concentrations can change rapidly in response to infection, tissue injury, or immune stimulation.\u003c\/p\u003e\u003ch2\u003eBiological function and signaling context\u003c\/h2\u003e\u003cp\u003eIn immune signaling networks, cytokine production is often induced by pattern-recognition pathways and inflammatory transcriptional programs, while feedback regulators can dampen responses to restore homeostasis. Chemokine gradients guide leukocyte migration, influencing which cell populations accumulate at a site and how long they persist.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune activation readout:\u003c\/strong\u003e Shifts in abundance can reflect pathway engagement and cellular activation state.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicroenvironment profiling:\u003c\/strong\u003e Levels can help characterize inflammatory tone in tissues or biofluids.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResponse monitoring:\u003c\/strong\u003e Time-course measurements support interpretation of stimulus, treatment, or infection models.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eDisease and translational relevance\u003c\/h2\u003e\u003cp\u003eMany cytokines and chemokines are reported to associate with inflammatory, autoimmune, infectious, and oncology-related processes. In research settings, interpreting changes benefits from pairing this analyte with complementary markers (e.g., upstream triggers, downstream effectors, and cell-type indicators) and considering matrix effects.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920821580141,"sku":"EK0735","price":513.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek0735_1fa8f802-12fe-4038-8f65-6e6961874a7c.png?v=1769077758"},{"product_id":"mouse-cxcl10-ip-10-elisa-kit-picokine-bhe21000594","title":"Mouse CXCL10\/IP-10 ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e C-X-C motif chemokine 10, 10 kDa interferon gamma-induced protein, Gamma-IP10, IP-10, C7, Interferon-gamma induced protein CRG-2, Small-inducible cytokine B10, Cxcl10.\u003c\/p\u003e\u003cp\u003eMouse \u003cstrong\u003eCXCL10\/IP-10\u003c\/strong\u003e (\u003cstrong\u003eCXCL10\u003c\/strong\u003e) is an established target in many assay panels, supporting hypothesis testing across diverse biological systems. This target is frequently investigated in \u003cstrong\u003eMolecular \u0026amp; Cellular Biology\u003c\/strong\u003e research contexts. Cytokines and chemokines act as soluble messengers that coordinate immune cell activation, trafficking, and effector functions. Their concentrations can change rapidly in response to infection, tissue injury, or immune stimulation.\u003c\/p\u003e\u003ch2\u003eBiological function and signaling context\u003c\/h2\u003e\u003cp\u003eIn immune signaling networks, cytokine production is often induced by pattern-recognition pathways and inflammatory transcriptional programs, while feedback regulators can dampen responses to restore homeostasis. Chemokine gradients guide leukocyte migration, influencing which cell populations accumulate at a site and how long they persist.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune activation readout:\u003c\/strong\u003e Shifts in abundance can reflect pathway engagement and cellular activation state.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicroenvironment profiling:\u003c\/strong\u003e Levels can help characterize inflammatory tone in tissues or biofluids.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResponse monitoring:\u003c\/strong\u003e Time-course measurements support interpretation of stimulus, treatment, or infection models.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eDisease and translational relevance\u003c\/h2\u003e\u003cp\u003eMany cytokines and chemokines are reported to associate with inflammatory, autoimmune, infectious, and oncology-related processes. In research settings, interpreting changes benefits from pairing this analyte with complementary markers (e.g., upstream triggers, downstream effectors, and cell-type indicators) and considering matrix effects.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920821612909,"sku":"EK0736","price":513.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek0736.png?v=1769077758"},{"product_id":"human-emmprin-cd147-bsg-elisa-kit-picokine-bhe21000603","title":"Human EMMPRIN\/CD147\/BSG ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Basigin, 5F7, Collagenase stimulatory factor, Extracellular matrix metalloproteinase inducer, EMMPRIN, Leukocyte activation antigen M6, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor.\u003c\/p\u003e\u003cp\u003eHuman \u003cstrong\u003eEMMPRIN\/CD147\/BSG\u003c\/strong\u003e (\u003cstrong\u003eBSG\u003c\/strong\u003e) is widely studied as a molecular readout in experimental models where changes in protein abundance reflect underlying biology. This target is frequently investigated in \u003cstrong\u003eInfectious Disease\u003c\/strong\u003e research contexts. Cytokines and chemokines act as soluble messengers that coordinate immune cell activation, trafficking, and effector functions. Their concentrations can change rapidly in response to infection, tissue injury, or immune stimulation.\u003c\/p\u003e\u003ch2\u003eBiological function and signaling context\u003c\/h2\u003e\u003cp\u003eIn immune signaling networks, cytokine production is often induced by pattern-recognition pathways and inflammatory transcriptional programs, while feedback regulators can dampen responses to restore homeostasis. Chemokine gradients guide leukocyte migration, influencing which cell populations accumulate at a site and how long they persist.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune activation readout:\u003c\/strong\u003e Shifts in abundance can reflect pathway engagement and cellular activation state.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicroenvironment profiling:\u003c\/strong\u003e Levels can help characterize inflammatory tone in tissues or biofluids.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResponse monitoring:\u003c\/strong\u003e Time-course measurements support interpretation of stimulus, treatment, or infection models.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eDisease and translational relevance\u003c\/h2\u003e\u003cp\u003eMany cytokines and chemokines are reported to associate with inflammatory, autoimmune, infectious, and oncology-related processes. In research settings, interpreting changes benefits from pairing this analyte with complementary markers (e.g., upstream triggers, downstream effectors, and cell-type indicators) and considering matrix effects.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920821907821,"sku":"EK0751","price":513.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek0751_3_8c870be5-f794-4dee-b4b9-0f0c27485570.png?v=1769077763"},{"product_id":"human-mif-elisa-kit-picokine-bhe21000631","title":"Human MIF ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Macrophage migration inhibitory factor, MIF.\u003c\/p\u003e\u003cp\u003eHuman \u003cstrong\u003eMIF\u003c\/strong\u003e (\u003cstrong\u003eMIF\u003c\/strong\u003e) is a commonly measured biological analyte that can provide insight into cellular state and tissue physiology. This target is frequently investigated in \u003cstrong\u003eMolecular \u0026amp; Cellular Biology\u003c\/strong\u003e research contexts. As with many protein targets, abundance can be influenced by transcriptional regulation, secretion or shedding, proteolytic processing, and clearance. Quantitative measurement is often used to connect molecular changes with phenotypes such as stress responses, immune activation, differentiation, or tissue remodeling.\u003c\/p\u003e\u003ch2\u003eBiological context and interpretation\u003c\/h2\u003e\u003cp\u003eProtein-level readouts complement nucleic-acid measurements by reflecting post-transcriptional control and protein stability. Depending on the model system, changes may be transient or sustained, and may represent direct pathway engagement or secondary effects. When interpreting results, consider sample matrix effects, timing relative to stimulation or treatment, and whether complexes or modified forms of the analyte may be present.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eComparative quantification:\u003c\/strong\u003e Supports analysis across experimental groups, time points, or dose ranges.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePathway context:\u003c\/strong\u003e Useful as part of a broader marker panel to triangulate biological mechanisms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eModel characterization:\u003c\/strong\u003e Helps profile baseline vs perturbed states in cells, tissues, or biofluids.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated pathways and interacting partners\u003c\/h2\u003e\u003cp\u003eFor many targets, interpretability improves when measured alongside biologically connected markers (e.g., upstream regulators, downstream effectors, and cell-type indicators). Designing panels around a pathway hypothesis can help distinguish primary pathway activation from general stress or inflammation.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920822825325,"sku":"EK0813","price":513.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek0813_006ed3a6-8f19-4f2e-9f46-3e4c0239d747.png?v=1769077775"},{"product_id":"human-comp-thrombospondin-5-elisa-kit-picokine-bhe21000690","title":"Human COMP\/Thrombospondin 5 ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Cartilage oligomeric matrix protein, COMP, Thrombospondin-5, TSP5.\u003c\/p\u003e\u003cp\u003eHuman \u003cstrong\u003eCOMP\/Thrombospondin 5\u003c\/strong\u003e (\u003cstrong\u003eCOMP\u003c\/strong\u003e) is widely studied as a molecular readout in experimental models where changes in protein abundance reflect underlying biology. This target is frequently investigated in \u003cstrong\u003eInfectious Disease\u003c\/strong\u003e research contexts. As with many protein targets, abundance can be influenced by transcriptional regulation, secretion or shedding, proteolytic processing, and clearance. Quantitative measurement is often used to connect molecular changes with phenotypes such as stress responses, immune activation, differentiation, or tissue remodeling.\u003c\/p\u003e\u003ch2\u003eBiological context and interpretation\u003c\/h2\u003e\u003cp\u003eProtein-level readouts complement nucleic-acid measurements by reflecting post-transcriptional control and protein stability. Depending on the model system, changes may be transient or sustained, and may represent direct pathway engagement or secondary effects. When interpreting results, consider sample matrix effects, timing relative to stimulation or treatment, and whether complexes or modified forms of the analyte may be present.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eComparative quantification:\u003c\/strong\u003e Supports analysis across experimental groups, time points, or dose ranges.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePathway context:\u003c\/strong\u003e Useful as part of a broader marker panel to triangulate biological mechanisms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eModel characterization:\u003c\/strong\u003e Helps profile baseline vs perturbed states in cells, tissues, or biofluids.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated pathways and interacting partners\u003c\/h2\u003e\u003cp\u003eFor many targets, interpretability improves when measured alongside biologically connected markers (e.g., upstream regulators, downstream effectors, and cell-type indicators). Designing panels around a pathway hypothesis can help distinguish primary pathway activation from general stress or inflammation.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920825315693,"sku":"EK0913","price":513.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek0913_1.png?v=1769077804"},{"product_id":"mouse-ace2-elisa-kit-picokine-bhe21000808","title":"Mouse ACE2 ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Angiotensin-converting enzyme 2, 3.4.17.23, ACE-related carboxypeptidase, Processed angiotensin-converting enzyme 2, Ace2.\u003c\/p\u003e\u003cp\u003eMouse \u003cstrong\u003eACE2\u003c\/strong\u003e (\u003cstrong\u003eACE2\u003c\/strong\u003e) is a commonly measured biological analyte that can provide insight into cellular state and tissue physiology. This target is frequently investigated in \u003cstrong\u003eMetabolism \u0026amp; Diabetes\u003c\/strong\u003e research contexts. As with many protein targets, abundance can be influenced by transcriptional regulation, secretion or shedding, proteolytic processing, and clearance. Quantitative measurement is often used to connect molecular changes with phenotypes such as stress responses, immune activation, differentiation, or tissue remodeling.\u003c\/p\u003e\u003ch2\u003eBiological context and interpretation\u003c\/h2\u003e\u003cp\u003eProtein-level readouts complement nucleic-acid measurements by reflecting post-transcriptional control and protein stability. Depending on the model system, changes may be transient or sustained, and may represent direct pathway engagement or secondary effects. When interpreting results, consider sample matrix effects, timing relative to stimulation or treatment, and whether complexes or modified forms of the analyte may be present.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eComparative quantification:\u003c\/strong\u003e Supports analysis across experimental groups, time points, or dose ranges.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePathway context:\u003c\/strong\u003e Useful as part of a broader marker panel to triangulate biological mechanisms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eModel characterization:\u003c\/strong\u003e Helps profile baseline vs perturbed states in cells, tissues, or biofluids.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated pathways and interacting partners\u003c\/h2\u003e\u003cp\u003eFor many targets, interpretability improves when measured alongside biologically connected markers (e.g., upstream regulators, downstream effectors, and cell-type indicators). Designing panels around a pathway hypothesis can help distinguish primary pathway activation from general stress or inflammation.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920831148397,"sku":"EK1188","price":513.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek1188.png?v=1769077865"},{"product_id":"mouse-lbp-elisa-kit-picokine-bhe21000864","title":"Mouse LBP ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Lipopolysaccharide-binding protein, LBP.\u003c\/p\u003e\u003cp\u003eMouse \u003cstrong\u003eLBP\u003c\/strong\u003e (\u003cstrong\u003eLBP\u003c\/strong\u003e) is an established target in many assay panels, supporting hypothesis testing across diverse biological systems. This target is frequently investigated in \u003cstrong\u003eMolecular \u0026amp; Cellular Biology\u003c\/strong\u003e research contexts. As with many protein targets, abundance can be influenced by transcriptional regulation, secretion or shedding, proteolytic processing, and clearance. Quantitative measurement is often used to connect molecular changes with phenotypes such as stress responses, immune activation, differentiation, or tissue remodeling.\u003c\/p\u003e\u003ch2\u003eBiological context and interpretation\u003c\/h2\u003e\u003cp\u003eProtein-level readouts complement nucleic-acid measurements by reflecting post-transcriptional control and protein stability. Depending on the model system, changes may be transient or sustained, and may represent direct pathway engagement or secondary effects. When interpreting results, consider sample matrix effects, timing relative to stimulation or treatment, and whether complexes or modified forms of the analyte may be present.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eComparative quantification:\u003c\/strong\u003e Supports analysis across experimental groups, time points, or dose ranges.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePathway context:\u003c\/strong\u003e Useful as part of a broader marker panel to triangulate biological mechanisms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eModel characterization:\u003c\/strong\u003e Helps profile baseline vs perturbed states in cells, tissues, or biofluids.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated pathways and interacting partners\u003c\/h2\u003e\u003cp\u003eFor many targets, interpretability improves when measured alongside biologically connected markers (e.g., upstream regulators, downstream effectors, and cell-type indicators). Designing panels around a pathway hypothesis can help distinguish primary pathway activation from general stress or inflammation.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920832983405,"sku":"EK1274","price":463.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek1274_c87b5777-fcef-4afa-a64e-fb0539e9e7c1.jpg?v=1769077899"},{"product_id":"human-lbp-elisa-kit-picokine-bhe21001028","title":"Human LBP ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Lipopolysaccharide-binding protein, LBP.\u003c\/p\u003e\u003cp\u003eHuman \u003cstrong\u003eLBP\u003c\/strong\u003e (\u003cstrong\u003eLBP\u003c\/strong\u003e) is an established target in many assay panels, supporting hypothesis testing across diverse biological systems. This target is frequently investigated in \u003cstrong\u003eMolecular \u0026amp; Cellular Biology\u003c\/strong\u003e research contexts. As with many protein targets, abundance can be influenced by transcriptional regulation, secretion or shedding, proteolytic processing, and clearance. Quantitative measurement is often used to connect molecular changes with phenotypes such as stress responses, immune activation, differentiation, or tissue remodeling.\u003c\/p\u003e\u003ch2\u003eBiological context and interpretation\u003c\/h2\u003e\u003cp\u003eProtein-level readouts complement nucleic-acid measurements by reflecting post-transcriptional control and protein stability. Depending on the model system, changes may be transient or sustained, and may represent direct pathway engagement or secondary effects. When interpreting results, consider sample matrix effects, timing relative to stimulation or treatment, and whether complexes or modified forms of the analyte may be present.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eComparative quantification:\u003c\/strong\u003e Supports analysis across experimental groups, time points, or dose ranges.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePathway context:\u003c\/strong\u003e Useful as part of a broader marker panel to triangulate biological mechanisms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eModel characterization:\u003c\/strong\u003e Helps profile baseline vs perturbed states in cells, tissues, or biofluids.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated pathways and interacting partners\u003c\/h2\u003e\u003cp\u003eFor many targets, interpretability improves when measured alongside biologically connected markers (e.g., upstream regulators, downstream effectors, and cell-type indicators). Designing panels around a pathway hypothesis can help distinguish primary pathway activation from general stress or inflammation.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920842551661,"sku":"EK1271","price":463.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek1271.jpg?v=1769077995"},{"product_id":"rat-alcam-cd166-elisa-kit-picokine-bhe21001131","title":"Rat ALCAM\/CD166 ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e CD166 antigen, Activated leukocyte cell adhesion molecule, HB2, KG-CAM, Protein MEMD, SB-10 antigen, CD166, Alcam.\u003c\/p\u003e\u003cp\u003eRat \u003cstrong\u003eALCAM\/CD166\u003c\/strong\u003e (\u003cstrong\u003eAlcam\u003c\/strong\u003e) is an established target in many assay panels, supporting hypothesis testing across diverse biological systems. This target is frequently investigated in \u003cstrong\u003eInfectious Disease\u003c\/strong\u003e research contexts. This analyte is often discussed in the context of \u003cstrong\u003ecell-surface signaling and cell-state markers\u003c\/strong\u003e. Many receptors and surface markers act as gateways for signaling or as phenotypic indicators of specific cell populations and activation states.\u003c\/p\u003e\u003ch2\u003eBiological context\u003c\/h2\u003e\u003cp\u003eIn experimental systems, protein abundance can reflect regulated expression, secretion, processing, or clearance. Interpreting changes benefits from considering compartment (cell-associated vs soluble), the time scale of regulation, and whether complexes or modified forms contribute to the measured signal.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystems-level readout:\u003c\/strong\u003e Quantification supports comparisons across conditions, time points, and treatment groups.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanistic interpretation:\u003c\/strong\u003e Pairing with upstream regulators and downstream markers helps contextualize changes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiomarker-style profiling:\u003c\/strong\u003e Measuring panels of related analytes can improve interpretability in complex models.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920854446445,"sku":"EK1572","price":513.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek1572_c7ecaedb-c08d-4450-a0fc-7cfd5f963e32.jpg?v=1769078054"},{"product_id":"monkey-primate-mif-elisa-kit-picokine-bhe21001245","title":"Monkey primate MIF ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Macrophage migration inhibitory factor, MIF.\u003c\/p\u003e\u003cp\u003eMonkey \u003cstrong\u003eprimate MIF\u003c\/strong\u003e (\u003cstrong\u003eMIF\u003c\/strong\u003e) is a commonly measured biological analyte that can provide insight into cellular state and tissue physiology. This target is frequently investigated in \u003cstrong\u003eMolecular \u0026amp; Cellular Biology\u003c\/strong\u003e research contexts. As with many protein targets, abundance can be influenced by transcriptional regulation, secretion or shedding, proteolytic processing, and clearance. Quantitative measurement is often used to connect molecular changes with phenotypes such as stress responses, immune activation, differentiation, or tissue remodeling.\u003c\/p\u003e\u003ch2\u003eBiological context and interpretation\u003c\/h2\u003e\u003cp\u003eProtein-level readouts complement nucleic-acid measurements by reflecting post-transcriptional control and protein stability. Depending on the model system, changes may be transient or sustained, and may represent direct pathway engagement or secondary effects. When interpreting results, consider sample matrix effects, timing relative to stimulation or treatment, and whether complexes or modified forms of the analyte may be present.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eComparative quantification:\u003c\/strong\u003e Supports analysis across experimental groups, time points, or dose ranges.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePathway context:\u003c\/strong\u003e Useful as part of a broader marker panel to triangulate biological mechanisms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eModel characterization:\u003c\/strong\u003e Helps profile baseline vs perturbed states in cells, tissues, or biofluids.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated pathways and interacting partners\u003c\/h2\u003e\u003cp\u003eFor many targets, interpretability improves when measured alongside biologically connected markers (e.g., upstream regulators, downstream effectors, and cell-type indicators). 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This target is frequently investigated in \u003cstrong\u003eOncology \u0026amp; Angiogenesis\u003c\/strong\u003e research contexts. This analyte is often discussed in the context of \u003cstrong\u003ecell-surface signaling and cell-state markers\u003c\/strong\u003e. Many receptors and surface markers act as gateways for signaling or as phenotypic indicators of specific cell populations and activation states.\u003c\/p\u003e\u003ch2\u003eBiological context\u003c\/h2\u003e\u003cp\u003eIn experimental systems, protein abundance can reflect regulated expression, secretion, processing, or clearance. Interpreting changes benefits from considering compartment (cell-associated vs soluble), the time scale of regulation, and whether complexes or modified forms contribute to the measured signal.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystems-level readout:\u003c\/strong\u003e Quantification supports comparisons across conditions, time points, and treatment groups.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanistic interpretation:\u003c\/strong\u003e Pairing with upstream regulators and downstream markers helps contextualize changes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiomarker-style profiling:\u003c\/strong\u003e Measuring panels of related analytes can improve interpretability in complex models.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920874172781,"sku":"EK0694","price":513.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek0694_173ab00b-6b3a-4174-b6df-de3b9066589d.png?v=1769078185"},{"product_id":"human-lilra3-cd85e-elisa-kit-picokine-bhe21001669","title":"Human LILRA3\/CD85e ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003eHuman \u003cstrong\u003eLILRA3\/CD85e\u003c\/strong\u003e (\u003cstrong\u003eLILRA3\u003c\/strong\u003e) is a commonly measured biological analyte that can provide insight into cellular state and tissue physiology. This target is frequently investigated in \u003cstrong\u003eInfectious Disease\u003c\/strong\u003e research contexts. This analyte is often discussed in the context of \u003cstrong\u003ecell-surface signaling and cell-state markers\u003c\/strong\u003e. Many receptors and surface markers act as gateways for signaling or as phenotypic indicators of specific cell populations and activation states.\u003c\/p\u003e\u003ch2\u003eBiological context\u003c\/h2\u003e\u003cp\u003eIn experimental systems, protein abundance can reflect regulated expression, secretion, processing, or clearance. Interpreting changes benefits from considering compartment (cell-associated vs soluble), the time scale of regulation, and whether complexes or modified forms contribute to the measured signal.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystems-level readout:\u003c\/strong\u003e Quantification supports comparisons across conditions, time points, and treatment groups.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanistic interpretation:\u003c\/strong\u003e Pairing with upstream regulators and downstream markers helps contextualize changes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiomarker-style profiling:\u003c\/strong\u003e Measuring panels of related analytes can improve interpretability in complex models.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920890130797,"sku":"EK2113","price":772.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek2113.png?v=1769078340"},{"product_id":"human-cathepsin-z-elisa-kit-picokine-bhe21001723","title":"Human Cathepsin Z ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003eHuman \u003cstrong\u003eCathepsin Z\u003c\/strong\u003e (\u003cstrong\u003eCTSZ\u003c\/strong\u003e) is an established target in many assay panels, supporting hypothesis testing across diverse biological systems. This target is frequently investigated in \u003cstrong\u003eInfectious Disease\u003c\/strong\u003e research contexts. Proteases and extracellular matrix (ECM) components are central to tissue architecture and remodeling. In many experimental contexts, changes in ECM-related proteins reflect shifts in cell adhesion, migration, barrier integrity, or matrix turnover.\u003c\/p\u003e\u003ch2\u003eBiological function and remodeling context\u003c\/h2\u003e\u003cp\u003eMatrix remodeling is influenced by the balance between synthesis and degradation, often regulated by inflammatory cues, mechanical stress, and growth-factor signaling. Protease activity can unmask or release bioactive fragments, while altered ECM composition can feed back on cell behavior through mechanotransduction and receptor engagement.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRemodeling readout:\u003c\/strong\u003e Quantification can support studies of fibrosis, wound repair, and invasion models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicroenvironment state:\u003c\/strong\u003e Levels may reflect stromal activation, barrier disruption, or matrix turnover.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMechanistic linkage:\u003c\/strong\u003e Pairing with inflammatory and growth-factor markers can clarify drivers of remodeling.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eDisease and translational relevance\u003c\/h2\u003e\u003cp\u003eECM remodeling and protease regulation are frequently discussed in the literature across oncology, cardiovascular, pulmonary, and inflammatory disease models. Interpretation of abundance should consider whether the measured analyte represents pro-forms, active forms, or fragments, and whether binding partners in the matrix influence detectability.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920894685549,"sku":"EK2178","price":513.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek2178.jpg?v=1769078363"},{"product_id":"human-lrg1-elisa-kit-picokine-bhe21001780","title":"Human LRG1 ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003eHuman \u003cstrong\u003eLRG1\u003c\/strong\u003e (\u003cstrong\u003eLRG1\u003c\/strong\u003e) is an established target in many assay panels, supporting hypothesis testing across diverse biological systems. This target is frequently investigated in \u003cstrong\u003eInfectious Disease\u003c\/strong\u003e research contexts. As with many protein targets, abundance can be influenced by transcriptional regulation, secretion or shedding, proteolytic processing, and clearance. Quantitative measurement is often used to connect molecular changes with phenotypes such as stress responses, immune activation, differentiation, or tissue remodeling.\u003c\/p\u003e\u003ch2\u003eBiological context and interpretation\u003c\/h2\u003e\u003cp\u003eProtein-level readouts complement nucleic-acid measurements by reflecting post-transcriptional control and protein stability. Depending on the model system, changes may be transient or sustained, and may represent direct pathway engagement or secondary effects. When interpreting results, consider sample matrix effects, timing relative to stimulation or treatment, and whether complexes or modified forms of the analyte may be present.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eComparative quantification:\u003c\/strong\u003e Supports analysis across experimental groups, time points, or dose ranges.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePathway context:\u003c\/strong\u003e Useful as part of a broader marker panel to triangulate biological mechanisms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eModel characterization:\u003c\/strong\u003e Helps profile baseline vs perturbed states in cells, tissues, or biofluids.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eRelated pathways and interacting partners\u003c\/h2\u003e\u003cp\u003eFor many targets, interpretability improves when measured alongside biologically connected markers (e.g., upstream regulators, downstream effectors, and cell-type indicators). Designing panels around a pathway hypothesis can help distinguish primary pathway activation from general stress or inflammation.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920897864045,"sku":"EK2233","price":513.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek2233.jpg?v=1769078390"},{"product_id":"mouse-cxcl10-ip-10-picokine-quick-elisa-kit-bhe21001843","title":"Mouse CXCL10\/IP-10 PicoKine® Quick ELISA Kit","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003eMouse \u003cstrong\u003eCXCL10\/IP-10\u003c\/strong\u003e (\u003cstrong\u003eCXCL10\u003c\/strong\u003e) is an established target in many assay panels, supporting hypothesis testing across diverse biological systems. This target is frequently investigated in \u003cstrong\u003eMolecular \u0026amp; Cellular Biology\u003c\/strong\u003e research contexts. Cytokines and chemokines act as soluble messengers that coordinate immune cell activation, trafficking, and effector functions. Their concentrations can change rapidly in response to infection, tissue injury, or immune stimulation.\u003c\/p\u003e\u003ch2\u003eBiological function and signaling context\u003c\/h2\u003e\u003cp\u003eIn immune signaling networks, cytokine production is often induced by pattern-recognition pathways and inflammatory transcriptional programs, while feedback regulators can dampen responses to restore homeostasis. Chemokine gradients guide leukocyte migration, influencing which cell populations accumulate at a site and how long they persist.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune activation readout:\u003c\/strong\u003e Shifts in abundance can reflect pathway engagement and cellular activation state.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicroenvironment profiling:\u003c\/strong\u003e Levels can help characterize inflammatory tone in tissues or biofluids.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResponse monitoring:\u003c\/strong\u003e Time-course measurements support interpretation of stimulus, treatment, or infection models.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eDisease and translational relevance\u003c\/h2\u003e\u003cp\u003eMany cytokines and chemokines are reported to associate with inflammatory, autoimmune, infectious, and oncology-related processes. In research settings, interpreting changes benefits from pairing this analyte with complementary markers (e.g., upstream triggers, downstream effectors, and cell-type indicators) and considering matrix effects.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920900485485,"sku":"FEK0736","price":513.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/fek0736.png?v=1769078425"},{"product_id":"primate-ifn-gamma-elisa-kit-picokine-bhe21001991","title":"Primate IFN-gamma ELISA Kit PicoKine®","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eAlso known as:\u003c\/strong\u003e Interferon gamma receptor 1, IFN-gamma receptor 1, IFN-gamma-R1, CDw119, CD119, IFNGR1.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePrimate IFN-gamma\u003c\/strong\u003e (\u003cstrong\u003eIFNG\u003c\/strong\u003e) is a commonly measured biological analyte that can provide insight into cellular state and tissue physiology. This target is frequently investigated in \u003cstrong\u003eInfectious Disease\u003c\/strong\u003e research contexts. Cytokines and chemokines act as soluble messengers that coordinate immune cell activation, trafficking, and effector functions. Their concentrations can change rapidly in response to infection, tissue injury, or immune stimulation.\u003c\/p\u003e\u003ch2\u003eBiological function and signaling context\u003c\/h2\u003e\u003cp\u003eIn immune signaling networks, cytokine production is often induced by pattern-recognition pathways and inflammatory transcriptional programs, while feedback regulators can dampen responses to restore homeostasis. Chemokine gradients guide leukocyte migration, influencing which cell populations accumulate at a site and how long they persist.\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune activation readout:\u003c\/strong\u003e Shifts in abundance can reflect pathway engagement and cellular activation state.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicroenvironment profiling:\u003c\/strong\u003e Levels can help characterize inflammatory tone in tissues or biofluids.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResponse monitoring:\u003c\/strong\u003e Time-course measurements support interpretation of stimulus, treatment, or infection models.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eDisease and translational relevance\u003c\/h2\u003e\u003cp\u003eMany cytokines and chemokines are reported to associate with inflammatory, autoimmune, infectious, and oncology-related processes. In research settings, interpreting changes benefits from pairing this analyte with complementary markers (e.g., upstream triggers, downstream effectors, and cell-type indicators) and considering matrix effects.\u003c\/p\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":52920907530605,"sku":"EK2375","price":513.97,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/ek2375.jpg?v=1769078504"},{"product_id":"16hbe14o-cell-bhc11101425","title":"16HBE14o- cell","description":"The 16HBE140 cell line is derived from human bronchial epithelial cells, which are essential for studying the respiratory epithelium. These cells retain several key characteristics of primary bronchial epithelial cells, including the ability to form tight junctions, express characteristic markers, and exhibit typical epithelial morphology. They are widely used in research focusing on respiratory diseases, drug transport, and toxicology studies, providing a reliable in vitro model to understand bronchial epithelial cell behavior under various conditions.\nOne of the significant applications of 16HBE140 cells is in the investigation of cystic fibrosis (CF), a genetic disorder affecting the respiratory system. These cells express the cystic fibrosis transmembrane conductance regulator (CFTR) protein, making them a valuable tool for studying CF pathophysiology and for screening potential therapeutic agents. Additionally, 16HBE140 cells are utilized in airway inflammation research, given their response to pro-inflammatory cytokines and pollutants, aiding in the understanding of chronic respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD).\n\u003cp style=\"display:none\"\u003eSKU:BHC11101425\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950195077485,"sku":"305234","price":800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/16HBE14o_20WaKo_20P1_2020x01_20181024_ch00_1920x1920_4dbb6d23-1d2b-4f74-9bc0-dd509475e130.jpg?v=1769068929"},{"product_id":"2106t-cell-bhc11100246","title":"2106T cell","description":"The 2106T cell line has been established from pulmonary squamous cell carcinoma of a patient by Dr. Sandra Gottschling and Dr. Michael Meister in 2009. The 2106LN cell line was isolated from a lymph node metastasis of the same patient.\n\u003cp style=\"display:none\"\u003eSKU:BHC11100246\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950195110253,"sku":"300165","price":800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/2106T_20WaKo_20P1_2010x01_20280525_ch00_1920x1920_b70a4584-a51c-45b5-a3cd-0b0b5953bc35.jpg?v=1769068930"},{"product_id":"2427t-cell-bhc11101374","title":"2427T cell","description":"Originating from a primary tumor of a 64-year-old female Caucasian patient diagnosed with lung squamous cell carcinoma, 2427T provides a valuable in vitro model that recapitulates the morphological traits of the original tumor tissue. Characterized by their distinctive small, round shape and propensity to aggregate into clusters, 2427T cells exhibit key morphological features typical of squamous cell carcinoma (SCC).\nA defining characteristic of the 2427T cell line is its expression of cytokeratin 5\/6 (CK5\/6), a marker indicative of its SCC origin. The heterogeneous expression of CK5\/6 hints at the presence of diverse cell subpopulations within the 2427T culture, presenting an opportunity for further exploration of intratumoral heterogeneity.\nImmunophenotyping of 2427T has revealed its unique profile, including the lack of adenocarcinoma-associated marker CK7, hemato-endothelial progenitor marker CD34, and leukocyte marker CD45, reinforcing its classification within the squamous lineage. Interestingly, while the cell line generally shows negativity for neuroendocrine markers such as CD56, synaptophysin (SYP), neuron-specific enolase (NSE), and chromogranin A (CHGA), the expression of SYP in a subset of cells suggests a degree of neuroendocrine marker heterogeneity.\nCrucially, the 2427T cell line does not harbor mutations in EGF-R or k-ras, distinguishing it from other models and underscoring its potential as a novel resource for delving into the biology and therapeutic vulnerabilities of squamous cell non-small cell lung cancer (NSCLC). This absence of common oncogenic mutations positions 2427T as an invaluable tool for research aimed at uncovering the underlying mechanisms of squamous cell carcinoma pathogenesis and progression.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101374\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950195208557,"sku":"300167","price":550.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/2427T_20P1_2020x01_20250425_ch00_1920x1920_ea96e0fc-18f0-4a17-adf8-1805029d5373.jpg?v=1769068931"},{"product_id":"a427-cell-bhc11100094","title":"A427 cell","description":"A427 cells originate from lung tissue, specifically a carcinoma, exhibit epithelial morphology and grow adherently. A427 cells have a doubling time of approximately 28 hours in RPMI 1640 medium supplemented with 10% fetal bovine serum (FBS). \nIn ACL-3 medium, the doubling time is slightly extended to 38 hours, while in ACL-3 supplemented with bovine serum albumin (BSA), it reaches 42 hours. These variations in doubling time provide valuable insights into cell behaviour under different experimental conditions.\nAt passage 60, A427 cells display a hypotriploid to hypertriploid karyotype. This means the cells possess abnormal chromosomes, including dicentrics, minutes, and a large subtelocentric marker. Such karyotypic abnormalities are often associated with cancer cells and contribute to the unique characteristics of this cell line. A427 cells exhibit tumorigenic properties, allowing them to form tumours when injected into nude mice. \nThese tumours resemble undifferentiated adenocarcinoma, further emphasizing the relevance of this cell line in studying lung cancer and its progression. With its exceptional features, A427 cells find utility in various applications, particularly in cancer research. Their epithelial morphology and lung origin make them an ideal model for studying lung cancer and related diseases. Additionally, A427 cells are well-suited for 3D cell culture techniques, providing a more physiologically relevant environment to explore the behaviour of lung cancer cells.\n\u003cp style=\"display:none\"\u003eSKU:BHC11100094\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950196257133,"sku":"300111","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/A427_20WaKo_20P1_2020x01_20080925_ch00_1920x1920_7109e5e2-5269-4661-9243-2a4765d4cecd.jpg?v=1769068938"},{"product_id":"a549-cell-bhc11100147","title":"A549 Cells","description":"A549 cells, derived from lung adenocarcinoma tissue, are a primary model used in cancer research, particularly in biomedical laboratories focusing on lung-related cancers. A549 cells are commonly used as an in vitro model for studying lung cancer biology, drug screening, and the effects of toxic compounds.\nIn toxicology research, A549 cells offer a controlled experimental model that enables scientists to explore the mechanisms underlying toxic effects and cellular responses. By understanding these mechanisms, researchers can better assess the safety of substances and potentially mitigate their harmful effects.\nA549 carcinoma cells have been extensively used as an in vitro model to study lung cancer pathogenesis and as an alternative tissue culture model for various pulmonary-related research studies in biomedical laboratories. These cells maintain the characteristics of type II alveolar epithelial cells and are used to examine the epithelial responses to various infections and inflammatory stimuli, including lung inflammation.\nFurthermore, the human cell line A549 serves as a valuable tool in the development of specific antibodies targeting lung cancer-related proteins or markers. By exposing these cells to substances of interest, researchers can investigate how they affect cell viability, proliferation, apoptosis, and other cellular processes. This information aids in the identification of potential therapeutic targets and the development of novel treatments for lung cancer.\nIn summary, A549 carcinoma cells are pivotal in cancer research, especially concerning lung-related cancers, serving as an in vitro model for cancer and toxicology research, developing effective treatments, and drug screening.\n\u003cp style=\"display:none\"\u003eSKU:BHC11100147\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950196355437,"sku":"300114","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/A549_20P35_20300114-1421_2020x01_2026082022_1920x1920_7da09e07-fa3c-451b-b408-9991b0e4cb71.jpg?v=1769068939"},{"product_id":"a549-ddp-cell-bhc11101352","title":"A549\/DDP cell","description":"The A549\/DDP cell line is a drug-resistant variant of the A549 cell line, which itself is a model of human alveolar basal epithelial adenocarcinoma. This variant has been specifically selected for its resistance to cisplatin (DDP), a common chemotherapy drug used in the treatment of various cancers, including lung cancer. The development of the A549\/DDP cell line enables researchers to study the mechanisms underlying chemoresistance, which is a major challenge in cancer therapy.\n\nIn research, the A549\/DDP cell line is utilized to investigate the biochemical pathways involved in cisplatin resistance. This includes the exploration of changes in gene expression, protein function, and cellular metabolism that confer resistance to cisplatin. The cell line is also valuable in the screening of new drugs or drug combinations that can overcome resistance, providing insights that are crucial for the development of more effective therapeutic strategies against lung cancer.\n\nMoreover, studies using the A549\/DDP cell line contribute to a better understanding of the molecular basis of lung cancer progression and metastasis in the context of chemoresistance. This cell line serves as a critical tool for translational research, bridging experimental findings to potential clinical applications in oncology.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101352\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950196486509,"sku":"305047","price":1500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/a549-ddp-_281_29.jpg?v=1769068939"},{"product_id":"asb-xiv-cell-bhc11100150","title":"ASB-XIV cell","description":"ASB-xIV cells, originating from a female Balb\/c mouse, closely mimic large cell carcinoma that has been induced by chrysotile asbestos in mouse lung cells. These cells are monolayer adherent with an epithelial morphology, positioning them as an exemplary model for primary squamous cell carcinoma (PSCC) research. Their structural and functional characteristics make them particularly suitable for detailed studies on the cellular processes and pathological mechanisms underlying PSCC.\n\nThe ASB-xIV cell line is characterized as an \"inflamed\" or \"hot\" tumor, indicating a high degree of immune cell infiltration which makes it more responsive to immunotherapy. This sensitivity is pivotal in using ASB-xIV cells to evaluate the efficacy of immune checkpoint therapies (ICT). These cells have shown significant responsiveness to such treatments, making them invaluable in oncological research focused on immunotherapeutic efficacy. Additionally, while retinoids have been effective in curbing the growth of these cells in transplanted carcinomas in mice, vitamin C has failed to produce a similar effect. Despite their slow doubling time of approximately 70 hours, ASB-xIV cells maintain robust and stable growth, which is crucial for establishing consistent and reliable in vitro cultures necessary for experimental reproducibility.\n\u003cp style=\"display:none\"\u003eSKU:BHC11100150\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950197535085,"sku":"400120","price":800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/asb-xiv-_284_29_1920x1920_809762c0-81cf-4ae2-a15f-eb17b6412e62.jpg?v=1769068948"},{"product_id":"beas-2b-cell-bhc11101339","title":"BEAS-2B Cells","description":"BEAS-2B is an immortalized cell line derived from the bronchial epithelium of a non-cancerous individual. This cell line was established by transforming human bronchial epithelial cells with an adenovirus 12-SV40 hybrid virus, which confers the cells with an extended lifespan while maintaining many of the morphological and functional characteristics typical of primary bronchial epithelial cells. BEAS-2B cells are widely used in respiratory disease research, particularly in studies related to the toxicological and pharmacological effects of inhalable substances, owing to their origin from the airway epithelium.\n\nThe cell line exhibits a cobblestone morphology when cultured and retains certain critical features, such as the ability to metabolize xenobiotic compounds, making them highly relevant for studies on drug metabolism and respiratory toxicology. They have also been employed extensively in studies exploring cellular mechanisms of asthma, chronic obstructive pulmonary disease (COPD), and cancer. BEAS-2B cells respond predictably to cytokines, oxidative stress, and other stimuli typical of respiratory tract exposure to environmental agents. This makes them a valuable model for studying inflammation and oxidative stress mechanisms in pulmonary cells.\n\nAs a tool in biomedical research, BEAS-2B cells are also frequently used to assess carcinogenic potential of airborne particles, where they serve as a model to understand the changes in airway epithelial cells following exposure to carcinogens. Their genetic makeup and susceptibility to genetic manipulation further enhance their utility in molecular biology experiments aimed at understanding gene expression and signaling pathways involved in lung diseases and cancer development.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101339\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950198059373,"sku":"300311","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/beas-2b-_289_29_1920x1920_f98cbff5-bfb9-4ddf-8f53-24d022c3bc51.jpg?v=1769068954"},{"product_id":"calu-1-cell-bhc11100243","title":"Calu-1 cell","description":"The Calu-1 cell line originates from human lung carcinoma, specifically non-small cell lung cancer (NSCLC). It was established from the pleural effusion of a 47-year-old Caucasian male with epidermoid carcinoma of the lung. This cell line exhibits epithelial-like morphology and has been used extensively in research focused on lung cancer biology, drug screening, and cytotoxicity studies. Calu-1 cells express several markers characteristic of lung epithelial cells and have been a valuable model for studying the molecular pathways involved in lung carcinogenesis and therapy resistance.\n\nCalu-1 cells are known for their high proliferation rate and robustness in culture, making them suitable for in vitro experimental setups. They retain several chromosomal abnormalities typical of cancer cells, which includes multiple copies of chromosomes 7 and 20, demonstrating their utility in genetic and cytogenetic studies. The cell line also exhibits mutations in key oncogenes and tumor suppressor genes like KRAS and TP53, respectively, which are of particular interest in lung cancer research. These genetic characteristics make Calu-1 a useful tool for investigating the impact of genetic alterations on cancer progression and for testing the efficacy of targeted therapies in a controlled environment.\n\u003cp style=\"display:none\"\u003eSKU:BHC11100243\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950200451437,"sku":"300141","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/CaLu-1_20WAKO_20P1_2020x01_20120825_ch00_1920x1920_b3989725-2c8c-4f44-a2b2-e7838e034a87.jpg?v=1769068982"},{"product_id":"calu-3-cell-bhc11101129","title":"Calu-3 cell","description":"Calu-3 cells are a human epithelial cell line derived from the lung adenocarcinoma of a 25-year-old in 1975. These cells exhibit epithelial morphology and are characterized by their ability to form tight junctions, desmosomes, and microvilli, mirroring the structural features of lung epithelium. Calu 3 cells are particularly noted for their high-level secretion of mucins, which are glycoproteins involved in protecting and lubricating the pulmonary airways, making them a relevant in vitro model for studying airway epithelial biology, including mucin production, secretion, and its regulation.\nCalu-3 human lung adenocarcinoma cells are used in drug discovery and development, particularly for assessing the absorption, distribution, metabolism, and excretion (ADME) of inhaled pharmaceuticals. Their ability to form a polarized monolayer when cultured on permeable supports makes them suitable for studying drug transport and the effects of drugs on the airway epithelium.\nCalu 3 cells, derived from human lung cancer cell types, are particularly relevant in the study of airway epithelial cells and their role in respiratory conditions. These cells originate from bronchial submucosal glands and are utilized in cell culture models to mimic the human airway, providing insights into respiratory function, epithelial cell injury, lung injury and the study of dieseases such as cystic fibrosis or SARS.\nThe study of Calu 3 cells and their response to chemotherapeutic agents contributes to the broader field of lung cancer research, offering insights into the efficacy of treatments and the potential for developing more effective therapeutic strategies.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101129\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950200484205,"sku":"305032","price":450.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/CaLu-3_20P0_20305032-M_2010x01_20270922_1920x1920_ffad64ab-b3bb-478c-a733-f3faa6f1c367.jpg?v=1769068982"},{"product_id":"calu-6-cell-bhc11100473","title":"Calu-6 cell","description":"The Calu-6 cell line is a human non-small cell lung carcinoma (NSCLC) cell line derived from the pleural effusion of a 61-year-old male patient. Established in 1975, this cell line has been a critical model in lung cancer research. Calu-6 cells exhibit a distinct epithelial morphology and have been used extensively to study the biology of lung cancer, including mechanisms of metastasis, drug resistance, and the tumor microenvironment. These cells are particularly noted for their ability to form tumors in xenograft models, which makes them highly valuable for in vivo studies of tumor growth and response to therapeutics.\n\nCalu-6 is characterized by a high level of KRAS mutation, common in NSCLC, and provides a relevant model for studying the role of this oncogene in lung cancer. The cell line also displays several cytogenetic anomalies typical of cancer cells, such as complex karyotypes and aneuploidy, which contribute to its use in genetic studies. Research utilizing the Calu-6 cell line has helped in understanding the cellular mechanisms of lung cancer and in the development of therapeutic strategies. Its robust growth in culture and the ability to mimic clinical aspects of lung cancer make it an indispensable resource in oncological research.\n\u003cp style=\"display:none\"\u003eSKU:BHC11100473\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950200516973,"sku":"300135","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/CaLu-6_20WaKo_20P1_2020x01_20090425_ch00_1920x1920_95d8b1cf-70e4-4211-b43b-fdfc3fbd8a6a.jpg?v=1769068983"},{"product_id":"ccd-18lu-cell-bhc11101465","title":"CCD-18Lu cell","description":"The CCD-18Lu cell line is derived from normal lung fibroblasts of a human adult. These cells were established from the lung tissue of a male patient and are commonly used as a model for studying the behavior of normal human lung fibroblasts. The CCD-18Lu cell line exhibits typical fibroblast morphology, characterized by spindle-shaped cells that grow adherently in culture and form a monolayer.\nResearchers utilize CCD-18Lu cells in various studies related to pulmonary biology, including investigations into lung development, repair, and fibrosis. These cells are instrumental in understanding the mechanisms underlying normal lung function and the response of lung fibroblasts to different environmental stimuli, such as cytokines, growth factors, and extracellular matrix components. Additionally, CCD-18Lu cells are employed in studies examining the effects of various drugs and compounds on lung fibroblast proliferation, differentiation, and collagen production.\nIn cancer research, CCD-18Lu cells serve as a control or reference cell line to compare with lung cancer cell lines, helping to identify specific molecular and cellular alterations associated with lung cancer progression. By providing insights into the behavior of normal lung fibroblasts, the CCD-18Lu cell line contributes to the development of therapeutic strategies for treating lung diseases, including fibrosis and cancer.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101465\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950200746349,"sku":"305248","price":550.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/CCD-18Lu_20WaKo_20P1_2010x01_20200924_ch00_1920x1920_0d936ecf-63cb-4077-a846-3be132c5f25a.jpg?v=1769068987"},{"product_id":"cls-54-cell-bhc11100653","title":"CLS-54 cell","description":"Established in vitro from the primary lung carcinoma of a 65 year-old man in 1998 by CLS.\n\u003cp style=\"display:none\"\u003eSKU:BHC11100653\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950201860461,"sku":"300227","price":650.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/cls-54-_281_29_1920x1920_b2c29cf6-6923-4c72-a1fe-b3c6de7be0d4.jpg?v=1769068997"},{"product_id":"dms-114-cell-bhc11101540","title":"DMS-114 cell","description":"DMS-114 is a human small-cell lung cancer (SCLC) cell line with unique features distinguishing it from other SCLC subtypes. Recent research has indicated that DMS-114, previously classified within the YAP1-expressing SCLC category (SCLC-Y), harbors pathogenic mutations in SMARCA4, an ATPase subunit of the SWI\/SNF chromatin-remodeling complex. These mutations are associated with the absence of RB1 mutations, contrary to the typical mutational landscape of SCLC, which commonly features concurrent TP53 and RB1 alterations. This cell line's profile includes reduced expression of SMARCA4 mRNA and protein, contributing to its reclassification as a SMARCA4-deficient undifferentiated tumor (SMARCA4-UT) rather than a traditional SCLC. Morphological assessments have shown that DMS-114 aligns more closely with thoracic SMARCA4-UT, exhibiting traits such as lower neuroendocrine marker expression and a distinctive immunohistochemical profile.\n\nThe revised classification of DMS-114 as a SMARCA4-deficient malignancy rather than SCLC has significant implications for its use as a preclinical model. It serves as an important resource for studying therapeutic strategies targeting SMARCA4-related pathways and investigating the biology of aggressive thoracic cancers that mimic SCLC. Unlike conventional SCLC, SMARCA4-deficient tumors, including DMS-114, often present with unique gene expression profiles marked by high YAP1 expression, loss of certain neuroendocrine markers, and distinct molecular vulnerabilities. This insight underscores the necessity of comprehensive molecular and histopathological analysis for accurate tumor classification and the development of effective treatment strategies.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101540\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950203040109,"sku":"305364","price":550.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/DMS-114_20P1_2020x01_20280325_ch00_1920x1920_104ef0a3-a780-4cf2-8409-198db59c429d.jpg?v=1769069010"},{"product_id":"dms-79-cell-bhc11100541","title":"DMS-79 cell","description":"DMS-79 is a human lung cancer cell line derived from a small cell lung carcinoma. These cells exhibit a classical neuroendocrine phenotype, which is characteristic of small cell lung cancer. This phenotype is significant because it implies a potential utility in studying neuroendocrine signaling pathways, which are crucial in the development and progression of lung cancer. The DMS-79 cell line has been widely utilized in research to understand the molecular biology of lung cancers, particularly in the context of tumor genesis, cell proliferation, and apoptosis.\n\nThe cell line is known for its aggressive growth and high tumorigenicity in vivo, making it an excellent model for in vivo studies of tumor behavior and response to therapeutics. DMS-79 cells also serve as a useful tool for pharmacological testing and drug development, offering insights into the cellular responses to various chemotherapeutic agents. Furthermore, these cells have been instrumental in the study of cancer stem cell characteristics and mechanisms of metastasis in small cell lung carcinoma. This extensive usage underscores the importance of DMS-79 in cancer research, particularly in therapies targeting aggressive and hard-to-treat cancers like small cell lung carcinoma.\n\u003cp style=\"display:none\"\u003eSKU:BHC11100541\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950203072877,"sku":"300164","price":550.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/DMS-79_20_20WaKo_20P1_2010x01_20021024_ch00_1920x1920_8fcfa439-ddfb-4cd4-875d-d869e11c61c9.jpg?v=1769069010"},{"product_id":"ebc-1-cell-bhc11101543","title":"EBC-1 cell","description":"EBC-1 is a human lung squamous cell carcinoma cell line, primarily noted for its relevance in studying mechanisms related to lung cancer, particularly non-small cell lung carcinoma (NSCLC). This cell line is characterized by MET gene amplification, which has been implicated in oncogenic signaling pathways that drive tumor growth and resistance to therapy. The MET receptor tyrosine kinase activation, typically induced by hepatocyte growth factor (HGF), plays a significant role in the proliferation, survival, and metastasis of these cells. Aberrations in MET signaling are pivotal in EBC-1’s aggressive tumor profile, making it an essential model for studying targeted therapies aimed at MET inhibition.\n\nResearch utilizing EBC-1 cells has explored various resistance mechanisms to MET inhibitors, such as crizotinib. The cell line has demonstrated acquired resistance via pathways involving PAI-1 upregulation and epithelial-to-mesenchymal transition (EMT), contributing to therapeutic challenges. Additionally, sodium butyrate has been shown to modulate gene expression in EBC-1 cells, indicating the potential utility of histone deacetylase inhibitors in affecting gene transcription. These findings underscore the importance of EBC-1 in both therapeutic resistance research and the development of novel treatment strategies for MET-amplified lung cancers.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101543\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950203433325,"sku":"305539","price":800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/EBC-1_20WaKo_20P1_2020x01_20080725_ch00_1920x1920_6bdb832c-caca-430c-bbd1-218c44048fef.jpg?v=1769069014"},{"product_id":"gct-cell-bhc11100759","title":"GCT cell","description":"The GCT cell line, originating from a giant cell tumor (GCT) isolated from the lung of an adult male patient with fibrous histiocytoma, is renowned for its robust biological activity in the field of medical research. This line produces Colony Stimulating Activity (CSA) for human granulocyte precursors and Erythropoietin-like Erythroid Activity (EEA) for erythroid precursors, making it invaluable for studying the regulation and development of hematopoietic cells. The granulocyte and erythroid precursors targeted by the GCT cell line's products are key to understanding processes like neutrophil function in the immune response and red blood cell formation, respectively.\n\nAdditionally, the medium conditioned by this cell line is a significant source of prostaglandin E and plasminogen activator. These substances have crucial roles in inflammatory responses and the fibrinolytic pathway, respectively. Prostaglandin E is essential for inflammatory modulation and maintaining physiological balance, while plasminogen activator contributes to the dissolution of blood clots. The presence of these factors in the GCT cell line's conditioned medium underscores its potential for developing therapeutic strategies addressing cardiovascular diseases and conditions related to excessive clot formation and inflammation.\n\u003cp style=\"display:none\"\u003eSKU:BHC11100759\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950204252525,"sku":"300155","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/gct-_284_29_1920x1920_78427e64-4f7c-45b8-b36a-a86321dc0d2d.jpg?v=1769069026"},{"product_id":"hara-b-cell-bhc11101139","title":"HARA-B cell","description":"The HARA-B cell line is derived from human squamous cell carcinoma of the lung, specifically established from metastatic bone tissue in a mouse model. This cell line is a secondary development from the original HARA cell line and is characterized by its high expression of parathyroid hormone-related protein (PTHrP), which plays a significant role in the extensive bone metastasis observed in these cells. The HARA-B line has been instrumental in studying the mechanisms of bone metastasis associated with lung cancer.\nScientific studies involving HARA-B often focus on its utility in modeling hypercalcemia, a common paraneoplastic syndrome associated with certain cancers, including lung cancer. The hypercalcemia in this model is induced by hypodermic transplantation of the cells, providing a valuable tool for understanding the interactions between cancer cells and bone cells, as well as the pathways that lead to bone degradation and calcium release. This cell line helps researchers investigate potential therapeutic strategies to mitigate bone metastasis and associated complications in lung cancer patients.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101139\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950204711277,"sku":"300465","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/hara-b_20_282_29_1920x1920_bf553e2c-ec16-490c-ad9e-19a1134601f8.jpg?v=1769069032"},{"product_id":"hcc366-cell-bhc11101395","title":"HCC366 cell","description":"HCC366 is a cell line derived from a non-small cell lung cancer (NSCLC) specifically categorized as lung adenocarcinoma. This cell line was established from the malignant pleural effusion of an 80-year old female patient. HCC366 is particularly noted for its characteristic expression of mutations in key oncogenes and tumor suppressor genes, which makes it a valuable model for studying the molecular mechanisms of lung adenocarcinoma and for testing therapeutic strategies targeted at these genetic alterations.\n\nIn research contexts, HCC366 has been utilized to explore the efficacy of various chemotherapeutic agents, as well as to understand resistance mechanisms to treatment. This cell line has also contributed to the investigation of the interaction between genetic mutations and response to targeted therapies, offering insights that are crucial for the development of personalized medicine approaches in lung cancer. Studies using HCC366 can help elucidate the biological behaviors typical of lung adenocarcinomas, such as cell proliferation, migration,\n\u003cp style=\"display:none\"\u003eSKU:BHC11101395\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950205071725,"sku":"302155","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/HCC366_20P1_2010x01_20280923_ch00_1920x1920_ad871d89-ff0b-4d75-8198-a375836a94dc.jpg?v=1769069037"},{"product_id":"hcc4006-cell-bhc11101694","title":"HCC4006 cell","description":"HCC4006 is a human non-small cell lung cancer (NSCLC) cell line derived from a lung adenocarcinoma. It is characterized by an activating exon 19 deletion in the EGFR gene, which makes it particularly sensitive to EGFR tyrosine kinase inhibitors (TKIs) such as erlotinib and gefitinib. This feature has made HCC4006 a widely used model for studying EGFR-mutant NSCLC and resistance mechanisms to EGFR-targeted therapies. In the Cancer Cell Line Encyclopedia (CCLE), HCC4006 has been comprehensively profiled at the genomic, transcriptomic, and epigenetic levels, confirming its high sensitivity to EGFR inhibition and highlighting its use as a pharmacogenomic reference model.\n\nHigh-resolution genomic studies have revealed that HCC4006 displays a relatively simple karyotype compared to other NSCLC models, which may facilitate clearer interpretation of drug responses and genomic alterations. It lacks common resistance mutations such as T790M in the EGFR gene, making it suitable for modeling initial treatment responses. However, resistance can be induced in vitro, allowing researchers to study mechanisms of acquired resistance. For example, resistance to EGFR TKIs in HCC4006 has been linked to epithelial-mesenchymal transition (EMT) and activation of alternative signaling pathways, such as AXL kinase overexpression.\n\nHCC4006 has also been assessed in large-scale transcriptomic comparisons of cell lines and primary tumors. It is one of the lung adenocarcinoma cell lines that demonstrates a moderate correlation to primary tumor gene expression profiles, though the degree of correlation can vary depending on the purity of the tumor samples used for comparison. These analyses underscore the relevance of HCC4006 in modeling certain molecular aspects of lung adenocarcinoma, particularly those associated with EGFR-driven oncogenesis, while also emphasizing its limitations in fully recapitulating the heterogeneity of primary tumors.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101694\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950205137261,"sku":"305785","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/HCC4006_20WAKO_20P1_2010x01_20120825_ch00_1920x1920_f2275c4a-eb49-41c9-a387-3149412ed77e.jpg?v=1769069037"},{"product_id":"hcc78-cell-bhc11101396","title":"HCC78 cell","description":"HCC78 is a cell line derived from a primary tumor of a lung adenocarcinoma, specifically a subtype known as mucinous bronchioloalveolar carcinoma. This cell line was established from a male adult patient. HCC78 cells are particularly noted for harboring a unique chromosomal rearrangement involving the ROS1 and SLC34A2 genes, which results in the SLC34A2-ROS1 fusion protein. This fusion protein has been implicated in oncogenic signaling pathways, making HCC78 a valuable model for studying the molecular mechanisms of ROS1 fusion-positive lung cancers and for testing targeted therapies against ROS1.\n\nIn research contexts, HCC78 has been utilized extensively to explore the efficacy and mechanism of action of ROS1 inhibitors. These studies have demonstrated the cell line's utility in preclinical assessments of drug sensitivity, resistance mechanisms, and the cellular pathways affected by ROS1 activity. The cell line grows adherently and exhibits epithelial-like morphology, which is characteristic of bronchioloalveolar tumors. The genetic and phenotypic features of HCC78 make it an essential tool for lung cancer research, especially for investigations focused on targeted therapies and personalized medicine in the treatment of ROS1-positive cancers.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101396\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950205202797,"sku":"302156","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/HCC78_20WaKo_20P1_2010x01_20131023_ch00_1920x1920_2dfc1061-c847-4f16-9915-9cc10e69e563.jpg?v=1769069038"},{"product_id":"hcc827-cell-bhc11101124","title":"HCC827 cell","description":"HCC827 is a human non-small cell lung cancer cell line derived from the lung adenocarcinoma of a middle-aged female patient. These cells exhibit an epithelial morphology and are often used in research related to the epidermal growth factor receptor (EGFR). HCC827 cells are particularly noted for their sensitivity to tyrosine kinase inhibitors (TKIs), specifically those targeting EGFR mutations. This characteristic makes them a valuable model for studying the molecular mechanisms of lung cancer responsiveness to EGFR inhibitors, as well as for testing the efficacy of new therapeutic agents targeting EGFR-dependent pathways.\n\nThe cell line is also used to explore the mechanisms of acquired resistance to targeted therapies, which is a significant challenge in the treatment of lung cancer. Studies utilizing HCC827 cells have contributed to a better understanding of the genetic and epigenetic alterations that confer resistance to EGFR inhibitors. These findings have implications for the development of strategies to overcome resistance and improve treatment outcomes in lung cancer patients. Furthermore, the HCC827 cell line serves as a tool for investigating the broader cellular and molecular landscape of lung adenocarcinoma, including studies on cell signaling, tumor microenvironment, and cancer metastasis.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101124\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950205235565,"sku":"305041","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/HCC827_20P0_20305041-M_2010x01_2014112022_1920x1920_aa02a22a-5322-4241-a65f-0c12b7ac66f5.jpg?v=1769069039"},{"product_id":"hel-299-cell-bhc11100446","title":"HEL-299 cell","description":"HEL-299 is a human lung fibroblast cell line derived from an adult individual. This cell line is particularly noted for its finite capacity to propagate in culture, typically entering senescence after approximately ten passages. This characteristic makes HEL-299 a useful model for studying cellular aging and senescence, as well as the dynamics of cell growth and replication under controlled conditions.\n\nIn addition to its applications in aging research, HEL-299 also serves as a model for studying signal transduction pathways. Specifically, it has been observed that the expression of the M2 muscarinic receptor in these cells is downregulated following stimulation with protein kinase C. This response highlights the cell line's utility in pharmacological research and in the investigation of mechanisms underlying receptor-mediated signaling and regulation. The alteration in receptor expression following kinase activity can provide insights into cellular responses to external stimuli, potentially aiding in the development of therapeutic strategies targeting similar pathways in various diseases.\n\u003cp style=\"display:none\"\u003eSKU:BHC11100446\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950206153069,"sku":"300193","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/hel-299-_284_29_1920x1920_be879006-347a-4af2-b379-2c1c7d014832.jpg?v=1769069048"},{"product_id":"hfl1-cell-bhc11101338","title":"HFL1 cell","description":"The HFL1 cell line, derived from human fetal lung tissue, is commonly used in biological and medical research. These cells exhibit fibroblast-like properties, making them particularly valuable for studies related to cellular morphology, fibrosis, and tissue repair mechanisms. HFL1 cells are instrumental in the exploration of pulmonary diseases, including investigations into the pathogenesis of lung fibrosis and the evaluation of antifibrotic therapies.\n\nIn addition to their application in disease models, HFL1 cells are often utilized in pharmacological research and toxicology studies. Their sensitivity to viral infections and responsiveness to pharmacological agents enable researchers to study the effects of various drugs and compounds on lung tissues. The HFL1 cell line supports the propagation of viruses, facilitating studies on viral life cycles and host-virus interactions, which are crucial for the development of antiviral drugs and vaccines.\n\nOverall, the HFL1 cell line is a versatile tool in the fields of respiratory disease research, pharmacology, and toxicology, providing insights into cellular processes and potential therapeutic approaches for lung-related diseases.\n\u003cp style=\"display:none\"\u003eSKU:BHC11101338\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950207463789,"sku":"305065","price":395.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/HFL1_20P1_20305065-M_2010x01_20011222_1920x1920_fa1ac987-bbff-4863-9af8-2326be466c73.jpg?v=1769069058"},{"product_id":"h-meso-1-cell-bhc11100791","title":"H-MESO-1 cell","description":"H-MESO-1 cells are a human mesothelioma cell line derived from a patient with malignant pleural mesothelioma, a type of cancer that develops from the cells lining the lungs' or abdomen's protective lining. This cell line is extensively used in oncological research to study the biology, pathogenesis, and therapeutic strategies for mesothelioma.\nH-MESO-1 cells retain several characteristics of mesothelial cells, making them a relevant model for investigating mesothelioma. They exhibit epithelioid morphology, which is one of the common histological types of mesothelioma. These cells are particularly useful for exploring the molecular pathways involved in mesothelioma development, including cell cycle regulation, apoptosis resistance, and the role of asbestos and other environmental factors in inducing mesothelioma.\nIn research, H-MESO-1 cells have been employed to study the interaction between mesothelioma cells and the immune system, especially considering the impact of immune checkpoint molecules and the tumor microenvironment on tumor growth and immune evasion. This cell line is also valuable for testing the efficacy of new drugs and novel immunotherapeutic approaches aimed at targeting specific pathways implicated in mesothelioma progression.\nMoreover, H-MESO-1 cells are used to investigate the genetic and epigenetic alterations characteristic of mesothelioma, providing insights into potential biomarkers for early diagnosis and targets for therapeutic intervention. The cell line's responsiveness to chemotherapeutic agents and its ability to form tumors in xenograft models make it a crucial tool in developing and validating new treatment modalities for mesothelioma.\n\u003cp style=\"display:none\"\u003eSKU:BHC11100791\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950208643437,"sku":"300186","price":800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/H-MESO-1_20WaKo_20P1_2010x01_20060325_ch00_1920x1920_dbc03c78-a715-4a06-8561-58020e1ccbad.jpg?v=1769069068"},{"product_id":"h-meso-1a-cell-bhc11100382","title":"H-MESO-1A cell","description":"The H-MESO-1A cell line is derived from human mesothelioma, a type of cancer that originates in the mesothelial cells lining the lungs, abdomen, or heart. This cell line is particularly valuable for research focused on understanding the pathophysiology of mesothelioma and the development of therapeutic strategies. Mesothelioma is often linked to asbestos exposure, and the H-MESO-1A cells can be used to study the molecular mechanisms underlying asbestos-induced carcinogenesis.\nH-MESO-1A cells exhibit the characteristic features of mesothelioma, including aggressive growth and resistance to conventional chemotherapy. They are utilized in preclinical studies to evaluate the efficacy of novel drugs, gene therapy approaches, and immunotherapy strategies. Researchers use this cell line to investigate the genetic and epigenetic alterations associated with mesothelioma, as well as to identify potential biomarkers for early diagnosis and prognosis. The H-MESO-1A cell line is an essential tool in the advancement of mesothelioma research and the quest for effective treatments.\n\u003cp style=\"display:none\"\u003eSKU:BHC11100382\u003c\/p\u003e","brand":"Cytion","offers":[{"title":"1 cryovial","offer_id":52950208676205,"sku":"300187","price":800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/h-meso-1a-_281_29_1920x1920_d53cdc7e-4286-4b20-99b6-611dc62aaa54.jpg?v=1769069068"}],"url":"https:\/\/www.ebiohippo.com\/collections\/infectious-disease.oembed","provider":"BioHippo","version":"1.0","type":"link"}