{"title":"Recombinant Protein Kinases (Human)","description":"\u003cp\u003eRecombinant human protein kinases for enzyme-activity, kinetics and inhibitor-screening assays — each supplied with a defined expression system and enzyme-activity application on the page. Includes AKT, ERK\/MAPK, MEK, receptor tyrosine kinases (ErbB, DDR1, TIE2) and more for IC₅₀ determination and pathway studies.\u003c\/p\u003e","products":[{"product_id":"recombinant-human-tyr-3-trp-5-monooxygenase-activation-protein-gamma-bhp11000851","title":"Recombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, Gamma","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, Gamma\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eThe 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms that have been identified in mammals. The 14-3-3gamma, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038063649133,"sku":"pka-238-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038310883693,"sku":"pka-238-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038310916461,"sku":"pka-238-1MG","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ywhag-human-PKA-238.png?v=1782158158"},{"product_id":"recombinant-human-tyr-3-trp-5-monooxygenase-activation-protein-eta-bhp11000848","title":"Recombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, ETA","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, ETA\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eYWHAH belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 ETA is found in plants and mammals, and there is 99% identity to the mouse, rat and bovine orthologs. YWHAH gene contains a 7 base pair repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia. 14-3-3 eta is specific to the site of joint inflammation. 14-3-3 proteins are colocalized with Lewy bodies in Parkinson disease, though there is no specific staining for the 14-3-3 eta subunit. There are 3 different isoforms types of 14-3-3: Beta, Gamma and ETA that are DAL-1\/Protein 4.1B-binding proteins.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038063812973,"sku":"pka-087-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038310490477,"sku":"pka-087-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038310523245,"sku":"pka-087-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-human-ywhah-PKA-087.png?v=1782158157"},{"product_id":"recombinant-human-tyr-3-trp-5-monooxygenase-activation-protein-beta-his-tag-bhp11000850","title":"Recombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, Beta, His Tag","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, Beta, His Tag\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eYWHAB belongs to the 14-3-3 family of proteins which are in charge for signal transduction by binding to phosphoserine-containing proteins. YWHAB is found in both plants and mammals. YWHAB protein interacts with RAF1 and CDC25 phosphatases,thus linking mitogenic signaling and the cell cycle machinery. YWHAB is an adapter protein involved in the regulation of a large spectrum of both general and specialized signaling pathway. YWHAB binds to a large number of proteins by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"1 ug","offer_id":53038063911277,"sku":"pka-096-1UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"5 ug","offer_id":53038311407981,"sku":"pka-096-5UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53038311440749,"sku":"pka-096-50UG","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ywhab-human-his-PKA-096.png?v=1782158157"},{"product_id":"recombinant-human-tyr-3-trp-5-monooxygenase-activation-protein-gamma-his-tag-bhp11000855","title":"Recombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, Gamma His Tag","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, Gamma His Tag\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eThe 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms that have been identified in mammals. The 14-3-3gamma, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038063944045,"sku":"pka-262-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038311539053,"sku":"pka-262-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038311571821,"sku":"pka-262-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ywhag-human-his-PKA-262.png?v=1782158161"},{"product_id":"recombinant-human-tyr-3-trp-5-monooxygenase-activation-protein-epsilon-bhp11000852","title":"Recombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, Epsilon","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, Epsilon\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eThe 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. The 14-3-3 epsilon, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038064009581,"sku":"pka-253-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038311080301,"sku":"pka-253-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038311113069,"sku":"pka-253-1MG","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ywhae-human-PKA-253.png?v=1782158158"},{"product_id":"recombinant-human-tyr-3-trp-5-monooxygenase-activation-protein-tau-bhp11000853","title":"Recombinant Human Tyr-3\/trp-5 Monooxygenase Activation Protein, Tau","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Tyr-3\/trp-5 Monooxygenase Activation Protein, Tau\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eThe 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, ?, ?, ?, ?, ?, ? and ? that have been identified in mammals. The 14-3-3 tau, a subtype of the 14-3-3 family of proteins, was found in T Cells, brain and testes. This 14-3-3 tau is upregulated in patients with amyotrophic lateral sclerosis.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038064042349,"sku":"pka-254-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038312259949,"sku":"pka-254-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038312292717,"sku":"pka-254-1MG","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ywhaq-human-PKA-254.png?v=1782158157"},{"product_id":"recombinant-human-tyr-3-trp-5-monooxygenase-activation-protein-epsilon-his-tag-bhp11000849","title":"Recombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, Epsilon, His Tag","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, Epsilon, His Tag\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eThe 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. The 14-3-3 epsilon, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038064238957,"sku":"pka-095-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038310424941,"sku":"pka-095-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53038310457709,"sku":"pka-095-100UG","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ywhae-human-his-PKA-095.png?v=1782158158"},{"product_id":"recombinant-human-activating-transcription-factor-4-bhp11000857","title":"Recombinant Human Activating Transcription Factor-4","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Activating Transcription Factor-4\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eActivating transcription factor 4 (ATF4) is a member of a family of DNA-binding proteins which includes the AP-1 family of transcription factors, cAMP-response element binding proteins and CREB-like proteins. The ATF4 gene encodes a transcription factor which was initially identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038064337261,"sku":"pka-006-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038312194413,"sku":"pka-006-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038312227181,"sku":"pka-006-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-atf4-human-PKA-006.png?v=1782158157"},{"product_id":"recombinant-human-activating-transcription-factor-3-bhp11000859","title":"Recombinant Human Activating Transcription Factor-3","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Activating Transcription Factor-3\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eATF3 belongs to the mammalian activation transcription factor\/cAMP responsive element-binding (CREB) protein family of transcription factors. ATF3 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in numerous viral and cellular promoters. Multiple transcript variants encoding two different isoforms are known for this gene. The longer isoform represses transcription from promoters with ATF binding elements instead of activating it. The shorter isoform (deltaZip2) which stimulates transcription by sequestering inhibitory co-factors away from the promoter has no leucine zipper protein-dimerization motif and does not bind to DNA.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038064370029,"sku":"pka-270-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038311801197,"sku":"pka-270-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038311833965,"sku":"pka-270-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-atf3-human-PKA-270.png?v=1782158159"},{"product_id":"recombinant-human-tyr-3-trp-5-mmonooxygenase-activation-protein-zeta-bhp11000854","title":"Recombinant Human Tyr- 3\/Trp-5 Mmonooxygenase Activation protein, Zeta","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Tyr- 3\/Trp-5 Mmonooxygenase Activation protein, Zeta\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eYWHAZ accession number NP_ 663723 belongs to the 14-3-3 family of proteins which are in charge for checkpoint control, apoptotic \u0026amp; nutrient sensing pathways as well as signal transduction by binding to phosphoserine-containing proteins. The 14-3-3 protein family is found in both plants and mammals, and KCIP-1 protein is 99% identical to the mouse, rat and sheep orthologs. KCIP-1 interacts with IRS1 protein, signifying a role in regulating insulin. 14-3-3 proteins are highly conserved and ubiquitously expressed. YWHAZ function as an adapter protein involved in the regulation of a large spectrum of both general and specialized signaling pathway. YWHAZ binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038064402797,"sku":"pka-257-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038311866733,"sku":"pka-257-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038311899501,"sku":"pka-257-1MG","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ywhaz-human-PKA-257.png?v=1782158157"},{"product_id":"recombinant-human-tyr-3-trp-5-monooxygenase-activation-protein-eta-his-tag-bhp11000856","title":"Recombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, ETA, His Tag","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, ETA, His Tag\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eYWHAH belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 ETA is found in plants and mammals, and there is 99% identity to the mouse, rat and bovine orthologs. YWHAH gene contains a 7 base pair repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia. 14-3-3 eta is specific to the site of joint inflammation. 14-3-3 proteins are colocalized with Lewy bodies in Parkinson disease, though there is no specific staining for the 14-3-3 eta subunit. There are 3 different isoforms types of 14-3-3: Beta, Gamma and ETA that are DAL-1\/Protein 4.1B-binding proteins.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038064468333,"sku":"pka-347-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038311014765,"sku":"pka-347-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038311047533,"sku":"pka-347-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ywhah-human-PKA-347.png?v=1782158157"},{"product_id":"recombinant-human-tyr-3-trp-5-monooxygenase-activation-protein-beta-bhp11000882","title":"Recombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, Beta","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Tyr-3\/Trp-5 Monooxygenase Activation Protein, Beta\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eYWHAB belongs to the 14-3-3 family of proteins which are in charge for signal transduction by binding to phosphoserine-containing proteins. YWHAB is found in both plants and mammals. YWHAB protein interacts with RAF1 and CDC25 phosphatases,thus linking mitogenic signaling and the cell cycle machinery. YWHAB is an adapter protein involved in the regulation of a large spectrum of both general and specialized signaling pathway. YWHAB binds to a large number of proteins by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038064533869,"sku":"pka-348-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038311932269,"sku":"pka-348-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038311965037,"sku":"pka-348-1MG","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ywhab-human-PKA-348.png?v=1782158158"},{"product_id":"recombinant-human-adenylate-kinase-5-bhp11000860","title":"Recombinant Human Adenylate Kinase 5","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Adenylate Kinase 5\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eAdenylate kinase isoenzyme 5 (AK5) belongs to the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. AK5 is related to the UMP\/CMP kinase of several species. AK5 is located in the cytosol and expressed exclusively in the brain.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038064566637,"sku":"pka-011-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038312325485,"sku":"pka-011-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038312358253,"sku":"pka-011-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ak5-human-PKA-011.png?v=1782158157"},{"product_id":"recombinant-human-adenosine-kinase-active-bhp11000864","title":"Recombinant Human Adenosine Kinase, Active","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Adenosine Kinase, Active\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eAdenosine Kinase is an abundant enzyme in mammalian tissues which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thus is as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has extensive effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme take a crucial pharmacological part in growing intravascular adenosine concentrations and acting as anti-inflammatory agents.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038064632173,"sku":"pka-108-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038311735661,"sku":"pka-108-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038311768429,"sku":"pka-108-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-adenosine-kinase-PKA-108.png?v=1782158161"},{"product_id":"recombinant-human-activating-transcription-factor-1-bhp11000858","title":"Recombinant Human Activating Transcription Factor-1","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Activating Transcription Factor-1\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eATF1, a cyclic-AMP dependent transcription factor, is expressed in a large selection of cell types and can dimerize with CREB. MSK1 and MSK2 protein kinases are essential for the stress-induced phosphorylation of transcription factors CREB and ATF1 in primary embryonic fibroblasts. Epidermal growth factor induction of c-jun expression needs ATF1 and MEF2 sites in the c-jun promoter.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038064730477,"sku":"pka-019-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038311145837,"sku":"pka-019-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038311178605,"sku":"pka-019-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-atf1-human-PKA-019.png?v=1782158157"},{"product_id":"recombinant-human-tyr-3-trp-5-monooxygenase-activation-protein-sigma-bhp11000883","title":"Recombinant Human Tyr-3\/trp-5 Monooxygenase Activation Protein, Sigma","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Tyr-3\/trp-5 Monooxygenase Activation Protein, Sigma\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eStratifin is part of the 14-3-3 family. The 14-3-3 family of proteins plays an important regulatory function in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are 7 isoforms, beta, gamma, epsilon, sigma, zeta, tau and eta that have been identified in mammals. Stratifin is an epithelial cell marker that functions as a tumor suppressor whose expression can be down regulated via methylation. Failure of Stratifin expression results in a defective G2\/M phase checkpoint and results in epithelial and non-epithelial tumorigenesis.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038064697709,"sku":"pka-357-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038312522093,"sku":"pka-357-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038312554861,"sku":"pka-357-1MG","price":2250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-stratifin-human-PKA-357.png?v=1782158159"},{"product_id":"recombinant-human-protein-kinase-casein-kinase-2-alpha-1-his-tag-bhp11000912","title":"Recombinant Human Protein kinase Casein Kinase 2 alpha 1, His Tag","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Protein kinase Casein Kinase 2 alpha 1, His Tag\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eThe Casein kinase 2 (EC2.7.11.1) is a serine\/threonine-selective protein kinasethat is a tetramer of two alpha subunits and two beta subunits. The alpha subunits have the catalytic kinase domain. Casein kinase 2 has been implicated in cell cyclecontrol, DNA repair, regulation of the circadian rhythmand other cellular processes. Casein kinase 2 activity has been reported to be activated following Wnt signaling pathwayactivation. A Pertussis toxin-sensitive G proteinand Disheveled appear to be an intermediary between Wnt-mediated activation of the Frizzled receptor and activation of casein kinase\u003cbr\u003e2. Mice that lack casein kinase 2 alpha prime have a defect in the morphology of developing sperm.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038064763245,"sku":"pka-225-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038314029421,"sku":"pka-225-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038314062189,"sku":"pka-225-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-csnk2a1-human-his-PKA-225.png?v=1782158159"},{"product_id":"recombinant-human-adenylate-kinase-4-bhp11000866","title":"Recombinant Human Adenylate Kinase 4","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Adenylate Kinase 4\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eAK4 belongs to the adenylate kinase family of enzymes. AK4 protein is restricted to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide structures in a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Hereditary mutations which cause AK4 deficiencies in erythrocytes have been associated to hemolytic anemia.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038064796013,"sku":"pka-267-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038312653165,"sku":"pka-267-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038312685933,"sku":"pka-267-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ak4-human-PKA-267.png?v=1782158157"},{"product_id":"recombinant-human-aurora-kinase-a-bhp11000889","title":"Recombinant Human Aurora Kinase A","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Aurora Kinase A\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eAURKA (Aurora Kinase A) belongs to the mitotic serine\/threonine kinases family. AURKA is a cell cycle-regulated kinase which may be involved in microtubule formation and\/or stabilization at the spindle pole during chromosome segregation. AURKA is found at the centrosome in interphase cells and at the spindle poles in mitosis. Since the AURKA expression is cell-cycle regulated, it is low in G1\/S, it accumulates during G2\/M, and it decreases rapidly after. AURKA is involved in important processes during mitosis and meiosis whose proper function is essential for healthy cell proliferation. In addition, AURKA plays an essential role in tumourigenesis and is overexpressed in various types of cancers. AURKA is strongly expressed in the testis, colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines and weakly in skeletal muscle, thymus and spleen. AURKA interacts with its substrates BORA and ARHGEF2, as well as with TACC1 and CPEB1. Defects in the AURKA gene cause numerical centrosome aberrations including aneuploidy. AURKA overexpression has been linked to chromosomal instability in colorectal cancer. AURKA expression may have a prognostic significance in ovarian carcinoma.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038064828781,"sku":"pka-350-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038313439597,"sku":"pka-350-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038313472365,"sku":"pka-350-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-aurka-human-PKA-350.png?v=1782158159"},{"product_id":"recombinant-human-calcium-and-integrin-binding-1-bhp11000895","title":"Recombinant Human Calcium and Integrin Binding 1","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Calcium and Integrin Binding 1\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCIB1 (Calcium and integrin binding 1) is regulatory protein with 50% homology to calmodulin and calcineurin B, that encodes a member of the calcium-binding protein family. CIB1 interacts with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. Also CIB1 is widely expressed and binds to a number of effectors, such as integrin ?IIb, PAK1, and polo-like kinases, in different tissues.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e\n\u003ch3\u003eActivity \u0026amp; assay information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePatent Protected Countries:\u003c\/strong\u003e The Sale of recombinant Human CIB1 by ProSpec is prohibited in the United States of America.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038064861549,"sku":"pka-345-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038312784237,"sku":"pka-345-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038312817005,"sku":"pka-345-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cib1-human-PKA-345.png?v=1782158160"},{"product_id":"recombinant-human-adenylate-kinase-2-bhp11000865","title":"Recombinant Human Adenylate Kinase 2","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Adenylate Kinase 2\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eAdenylate kinases play a role in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. There are 3 types of adenylate kinase isozymes, AK1, AK2, and AK3 in vertebrates. Expression of these isozymes are tissue-specific and developmentally regulated. AK2 is localized in the mitochondrial intermembrane space and is involved in apoptosis. AK2 is mutated in individuals with reticular dysgenesis.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038064894317,"sku":"pka-260-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038312128877,"sku":"pka-260-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038312161645,"sku":"pka-260-1MG","price":4500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ak2-human-PKA-260.png?v=1782158157"},{"product_id":"recombinant-human-adenylate-kinase-1-bhp11000867","title":"Recombinant Human Adenylate Kinase 1","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Adenylate Kinase 1\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eAK1 is a small ubiquitous enzyme which is essential for maintenance and cell growth. It is involved in the regulation of adenine nucleotide composition within a cell by catalyzing the reversible transfer of the terminal phosphate group between ATP and AMP. The AK1 protein is found in the cytosol of skeletal muscle, brain and erythrocytes. Defects in the AK1 gene are the cause of a form of hemolytic anemia.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038064927085,"sku":"pka-316-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038312391021,"sku":"pka-316-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038312423789,"sku":"pka-316-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ak1-human-PKA-316.png?v=1782158159"},{"product_id":"recombinant-human-casein-kinase-2-alpha-2-prime-bhp11000906","title":"Recombinant Human Casein Kinase 2, Alpha 2 Prime","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Casein Kinase 2, Alpha 2 Prime\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCasein kinase 2 subunit alpha (CSNK2A2) controls numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. CSNK2A2 protein functions as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038065025389,"sku":"pka-042-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038312587629,"sku":"pka-042-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038312620397,"sku":"pka-042-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-csnk2a2-human-PKA-042.png?v=1782158161"},{"product_id":"recombinant-human-casein-kinase-2-beta-bhp11000911","title":"Recombinant Human Casein Kinase 2 beta","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Casein Kinase 2 beta\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCasein Kinase 2 also called CK2 (also called PKCK2) is a ubiquitous Ser\/Thr kinase expressed in all eukaryotes. CK2 is a tetramer composed of two catalytic kinase domains, alpha subunits, and two identical regulatory beta subunits. It has been implicated in cell cycle control, DNA repair, regulation of the circadian rhythm, and other cellular processes. The beta subunit itself does not have kinase activity, but confers stability to the CK2 alpha subunit and is involved in activity and substrate specificity.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038065123693,"sku":"pka-223-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038313701741,"sku":"pka-223-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038313734509,"sku":"pka-223-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-csnk2b-human-PKA-223.png?v=1782158159"},{"product_id":"recombinant-human-casein-kinase-1-alpha-1-bhp11000907","title":"Recombinant Human Casein Kinase 1 alpha 1","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Casein Kinase 1 alpha 1\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCaseine Kinase 1 alpha belongs is a member of the protein kinase superfamily, CK1 Ser\/Thr protein kinase family, Casein kinase I subfamily. The CK1 isoforms - alpha, beta, gamma, delta, epsilon and their splice variants are involved in diverse cellular processes including membrane trafficking, circadian rhythm, cell cycle progression, chromosome segregation, apoptosis and cellular differentiation. Possibly CSNK1A1 can phosphorylate a large number of proteins and is involved in Wnt signaling where it phosphorylates CTNNB1 on Ser45. CSNK1A1 also interacts with the Axin complex.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038065156461,"sku":"pka-056-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038312456557,"sku":"pka-056-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038312489325,"sku":"pka-056-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-csnk1a1-human-PKA-056.png?v=1782158160"},{"product_id":"recombinant-human-calcium-and-integrin-binding-2-bhp11000894","title":"Recombinant Human Calcium and Integrin Binding 2","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Calcium and Integrin Binding 2\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCIB2 is a member of the calcium and integrin-binding family.CIB2 is possibly a Ca2+-binding regulatory protein which interacts with DNA-dependent protein kinase catalytic subunit (DNA-PKcs). In the skeletal muscle, CIB2 co-localizes with the integrin alpha7B subunit at the sarcolemma and at the neuromuscular and myotendinous junctions. CIB2 is closely related to CIB1.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038065189229,"sku":"pka-268-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038312718701,"sku":"pka-268-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038312751469,"sku":"pka-268-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cib2-human-PKA-268.png?v=1782158158"},{"product_id":"recombinant-human-aurora-kinase-b-bhp11000890","title":"Recombinant Human Aurora Kinase B","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Aurora Kinase B\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eAurora Kinase B (AURKB) belongs to a family of mitotic serine\/threonine kinases. AURKB connects with chromosomes for the period of prophase prior to relocalizing to the spindle at anaphase. AURKB localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers. AURKB controls chromosome segregation through the control of microtubule-kinetochore attachment and cytokinesis. AURKB is required for kinetochore localization of BUB1 and SGOL1. AURKB expression during the G2\/M phase transition is firmly coordinated with histone H3 phosphorylation, while overexpression is seen in many kinds of cancers. AURKB phosphorylates 'Ser-10' and 'Ser-28' of histone H3 during mitosis. AURKB is a component of the CPC (chromosomal passenger complex), which is a complex that acts as a key regulator of mitosis. High level expression of AURKB is seen in the thymus, which is also expressed in the spleen, lung, testis, colon, placenta and fetal liver. AURKB is expressed during S and G2\/M phase and expression is up-regulated in cancer cells during M phase.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038065221997,"sku":"pka-355-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038313636205,"sku":"pka-355-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038313668973,"sku":"pka-355-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-aurkb-human-PKA-355.png?v=1782158162"},{"product_id":"recombinant-human-cyclin-dependent-kinase-2-associated-protein-2-bhp11000953","title":"Recombinant Human Cyclin-Dependent Kinase 2 Associated Protein 2","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Cyclin-Dependent Kinase 2 Associated Protein 2\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCyclin-Dependent Kinase 2 Associated Protein 2 (CDK2AP2) is a member of the CDK2AP family. CDK2-associated protein is assumed to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. CDK2AP2 is implicated in the regulation of self-renewal of stem cells during early embryogenesis. CDK2AP2 is a regulator for self-renewal of mESCs (mouse embryonic stem cells) under permissive conditions, and cell survival during differentiation of the mESCs into terminally differentiated cell types.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038065320301,"sku":"pka-048-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038314619245,"sku":"pka-048-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038314652013,"sku":"pka-048-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cdk2ap2-human-PKA-048.png?v=1782158162"},{"product_id":"recombinant-human-casein-kinase-2-holoenzyme-bhp11000910","title":"Recombinant Human Casein Kinase 2 Holoenzyme","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Casein Kinase 2 Holoenzyme\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e\n\u003ch3\u003eActivity \u0026amp; assay information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnit Definition:\u003c\/strong\u003e No protease activity detectable, specific activity \u0026gt; 1.3U\/mg (1U = 1µmol\/min at 37 degree C) using the synthetic peptide RRRDDDSDDD.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"3 ug","offer_id":53038065353069,"sku":"pka-211-3UG","price":400.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038313046381,"sku":"pka-211-10UG","price":800.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038313079149,"sku":"pka-211-20UG","price":1500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ck2h-human-PKA-211.png?v=1782158159"},{"product_id":"recombinant-human-cyclin-dependent-kinase-3-bhp11000954","title":"Recombinant Human cyclin-dependent kinase 3","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human cyclin-dependent kinase 3\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCyclin-dependent kinase 3, also known as CDK3, is a part of the cyclin-dependent protein kinase family. CDK3 promotes entry into S phase, partially by activating members of the E2F family of transcription factors. CDK3 also associates with cyclin C and phosphorylates the retinoblastoma one protein to promote exit from G0.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038065418605,"sku":"pka-055-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038314553709,"sku":"pka-055-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038314586477,"sku":"pka-055-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cdk3-human-PKA-055.png?v=1782158162"},{"product_id":"recombinant-human-cyclin-dependent-kinase-5-bhp11000952","title":"Recombinant Human cyclin-dependent kinase 5","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human cyclin-dependent kinase 5\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCell division protein kinase 5 (CDK5) belongs to the cyclin-dependent kinase family. CDK5 is essential for appropriate development of the brain and in order to be activated CDK5 must link to CDK5R1 or CDK5R2. CDK5 doesn't need phosphorylation on the T loop so that binding with the activator is enough to activate the kinase. CDK5 is engaged in the processes of neuronal maturation and migration, phosphorylating the central intracellular adaptor of the reeling signaling chain.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038065451373,"sku":"pka-047-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038314160493,"sku":"pka-047-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038314193261,"sku":"pka-047-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cdk5-human-PKA-047.png?v=1782158160"},{"product_id":"recombinant-human-adenosine-kinase-bhp11000869","title":"Recombinant Human Adenosine Kinase","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Adenosine Kinase\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eAdenosine Kinase is an abundant enzyme in mammalian tissues which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thus is as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has extensive effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme take a crucial pharmacological part in growing intravascular adenosine concentrations and acting as anti-inflammatory agents.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038065516909,"sku":"pka-367-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038313505133,"sku":"pka-367-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038313537901,"sku":"pka-367-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-adk-human-PKA-367.png?v=1782158158"},{"product_id":"recombinant-human-casein-kinase-1-delta-bhp11000913","title":"Recombinant Human Casein Kinase 1 Delta","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Casein Kinase 1 Delta\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCasein kinase I gene family members take part in the control of cytoplasmic and nuclear processes, including DNA replication and repair. Casein Kinase 1 Delta (CSNK1D) is a member of the casein kinase I (CKI) gene family. CSNK1D is a vital serine\/threonine-protein kinase which regulates diverse cellular growth and survival processes including Wnt signaling and circadian rhythms. CSNK1D phosphorylates a great amount of proteins.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038065549677,"sku":"pka-306-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038312849773,"sku":"pka-306-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038312882541,"sku":"pka-306-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-csnk1d-human-PKA-306.png?v=1782158159"},{"product_id":"recombinant-human-cyclin-dependent-kinase-inhibitor-2c-bhp11000951","title":"Recombinant Human Cyclin-Dependent Kinase Inhibitor 2C","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Cyclin-Dependent Kinase Inhibitor 2C\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCDKN2C is a member of the CDKN2 cyclin-dependent kinase inhibitor family. CDKN2C cooperates with CDK4 or CDK6, and inhibits the activation of the CDK kinases, therefore acts as a cell growth regulator which regulates cell cycle G1 progression. CDKN2C suppresses the cell growth and proliferation with a correlated dependency on endogenous retinoblastoma protein RB. Studies in the knockout mice show CDKN2C takes part in regulating spermatogenesis, in addition to suppressing tumorigenesis.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038065582445,"sku":"pka-020-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038313963885,"sku":"pka-020-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038313996653,"sku":"pka-020-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cdkn2c-human-PKA-020.png?v=1782158160"},{"product_id":"recombinant-human-adenylate-kinase-3-like-1-bhp11000868","title":"Recombinant Human Adenylate Kinase 3 Like 1","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Adenylate Kinase 3 Like 1\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eAK3L1 is an affiliate of the adenylate kinase family of enzymes. AK3L1 enzyme is restricted to the mitochondrial matrix. Adenylate kinases-3 regulates the adenine and guanine nucleotide compositions within a cell by means of catalyzing the reversible transfer of phosphate group among these nucleotides. 5 different isozymes of adenylate kinase have been identified in vertebrates. The enzyme expression of various adenylate kinase isozymes is growth regulated and tissue-specific.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038065615213,"sku":"pka-346-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038312063341,"sku":"pka-346-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038312096109,"sku":"pka-346-1MG","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ak3l1-human-PKA-346.png?v=1782158163"},{"product_id":"recombinant-human-cyclin-b2-bhp11000943","title":"Recombinant Human Cyclin-B2","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Cyclin-B2\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCCNB2 is a member of the cyclin family. CCNB2 is vital for regulation of the cell cycle at the G2\/M (mitosis) transition. CCNB2 cooperates with the CDK1 protein kinase to create a serine\/threonine kinase holoenzyme complex recognized as maturation promoting factor (MPF).\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038065647981,"sku":"pka-035-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038314357101,"sku":"pka-035-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038314389869,"sku":"pka-035-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ccnb2-human-PKA-035.png?v=1782158164"},{"product_id":"recombinant-human-casein-kinase-2-alpha-1-bhp11000908","title":"Recombinant Human Casein Kinase 2 alpha 1","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Casein Kinase 2 alpha 1\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eThe Casein kinase 2 (EC2.7.11.1) is a serine\/threonine-selective protein kinasethat is a tetramer of two alpha subunits and two beta subunits. The alpha subunits have the catalytic kinase domain. Casein kinase 2 has been implicated in cell cyclecontrol, DNA repair, regulation of the circadian rhythmand other cellular processes. Casein kinase 2 activity has been reported to be activated following Wnt signaling pathwayactivation. A Pertussis toxin-sensitive G proteinand Disheveled appear to be an intermediary between Wnt-mediated activation of the Frizzled receptor and activation of casein kinase\u003cbr\u003e2. Mice that lack casein kinase 2 alpha prime have a defect in the morphology of developing sperm.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e\n\u003ch3\u003eActivity \u0026amp; assay information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnit Definition:\u003c\/strong\u003e No protease activity detectable, specific activity \u0026gt; 1.320 U\/mg (1U = 1µmol\/min at 37 degree C) using the synthetic peptide RRRDDDSDDD.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"3 ug","offer_id":53038065680749,"sku":"pka-208-3UG","price":400.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038313374061,"sku":"pka-208-10UG","price":800.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038313406829,"sku":"pka-208-20UG","price":1500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-csnk2a1-human-PKA-208.png?v=1782158161"},{"product_id":"recombinant-human-cyclin-dependent-kinase-2-bhp11000949","title":"Recombinant Human cyclin-dependent kinase 2","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human cyclin-dependent kinase 2\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCyclin-dependent kinase 2 (CDK2) belongs the Ser\/Thr protein kinase family. CDK2 is highly parallel to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. CDK2 is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is limited to the G1-S phase, and is vital for cell cycle G1\/S phase transition. The CDK2 protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). CDK2 activity is also regulated by protein phosphorylation.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038065779053,"sku":"pka-008-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038314881389,"sku":"pka-008-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038314914157,"sku":"pka-008-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cdk2-human-PKA-008.png?v=1782158160"},{"product_id":"recombinant-human-cyclin-dependent-kinase-1-bhp11000957","title":"Recombinant Human cyclin-dependent kinase 1","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human cyclin-dependent kinase 1\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCyclin-dependent kinase 1 (CDK1) plays a significant part in the control of the eukaryotic cell cycle through modulating the centrosome cycle in addition to mitotic onset; CDK1 promotes G2-M transition and regulates G1 progress and G1-S transition using association with multiple interphase cyclins. CDK1 is essential in higher cells for the entry into S-phase and mitosis.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038065811821,"sku":"pka-076-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038314815853,"sku":"pka-076-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038314848621,"sku":"pka-076-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cdk1-human-PKA-076.png?v=1782158161"},{"product_id":"recombinant-human-cyclin-h-bhp11000946","title":"Recombinant Human Cyclin-H","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Cyclin-H\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCCNH is part of the cyclin family that is known for its protein abundance through the cell cycle. Cyclins act as regulators of CDK kinases. CCNH forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, therefore it functions as a CDK-activating kinase (CAK). CCNH and its kinase collaborator are components of TFIIH, as well as RNA polymerase II protein complexes.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038065844589,"sku":"pka-364-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038316978541,"sku":"pka-364-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038317011309,"sku":"pka-364-1MG","price":2250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ccnh-human-PKA-364.png?v=1782158159"},{"product_id":"recombinant-human-cyclin-b1-bhp11000944","title":"Recombinant Human Cyclin-B1","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Cyclin-B1\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCyclin B1 (CCNB1) is a regulatory protein involved in mitosis. CCNB1 creates a complex with p34(cdc2) to form the maturation-promoting factor (MPF). CCNB1 is vital for the control of the cell cycle at the G2\/M (mitosis) transition. CCNB1 builds up steadily during the G2 and is immediately destroyed at mitosis. The 2 alternative transcripts produce a constitutively expressed transcript and a cell cycle-regulated transcript which is expressed predominantly during G2\/M phase. These transcripts are a result of alternate transcription initiation sites.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038065877357,"sku":"pka-037-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038314291565,"sku":"pka-037-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53038314324333,"sku":"pka-037-100UG","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ccnb1-human-PKA-037.png?v=1782158161"},{"product_id":"recombinant-human-cyclin-dependent-kinase-inhibitor-1b-bhp11000950","title":"Recombinant Human Cyclin-Dependent Kinase Inhibitor 1B","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Cyclin-Dependent Kinase Inhibitor 1B\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCyclin-dependent kinase inhibitor 1B (CDKN1B) is a member of the Cip\/Kip family of cyclin dependent kinase (Cdk) inhibitor proteins. The CDKN1B protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and so controls the cell cycle progression at G1. CDKN1B is often referred to as a cell cycle inhibitor protein since its major function is to stop or slow down the cell division cycle. The degradation of the CDKN1B protein, which is triggered by its CDK dependent phosphorylation and ensuing ubiquitination by SCF complexes, is compulsory for the cellular transition from inactive to the proliferative state.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038065942893,"sku":"pka-012-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038315274605,"sku":"pka-012-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038315307373,"sku":"pka-012-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cdkn1b-human-PKA-012.png?v=1782158161"},{"product_id":"recombinant-human-cyclin-a2-bhp11000942","title":"Recombinant Human Cyclin-A2","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Cyclin-A2\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCCNA2 is a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins act as regulators of CDK kinases. Various cyclins demonstrate distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Contrary to cyclin A1, which is present only in germ cells, CCNA2 is expressed in all tissues tested. CCNA2 binds and activates CDC2 or CDK2 kinases, and consequently promotes both cell cycle G1\/S and G2\/M transitions.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038065975661,"sku":"pka-033-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038314422637,"sku":"pka-033-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038314455405,"sku":"pka-033-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ccna2-human-PKA-033.png?v=1782158161"},{"product_id":"recombinant-human-cyclin-dependent-kinase-inhibitor-2a-tat-bhp11000961","title":"Recombinant Human Cyclin-Dependent Kinase Inhibitor 2A TAT","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Cyclin-Dependent Kinase Inhibitor 2A TAT\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCyclin-dependent kinase inhibitors (CDKIs) are proteins that bind to and inhibit the activity of CDKs. Two major classes of CDK inhibitors have been identified. The p16 family (p15, p16, p18 and p19) binds to and inhibits the activities of CDK4 and CDK6. The p21 family (p21, p27, p28 and p57) can bind to broad range of CDK-cyclin complexes and inhibit their activities. CDKIs are capable of suppressing growth, and several lines of evidence strongly suggest that at least some CDKIs may be tumor suppressor proteins.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038066041197,"sku":"pka-337-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038315733357,"sku":"pka-337-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038315766125,"sku":"pka-337-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-p16-ink4a-human-tat-PKA-337.png?v=1782158162"},{"product_id":"recombinant-human-cyclin-dependent-kinase-4-bhp11000959","title":"Recombinant Human cyclin-dependent kinase 4","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human cyclin-dependent kinase 4\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCyclin-dependent kinase 4 combines with the protein cyclin D to form a protein complex that promotes the passage of cells through the G1 checkpoint in the cell growth cycle. This cellular activity is regulated by the protein p16 produced by p16INK4a. Normally, p16 controls cell growth by inhibiting the activity of the CDK4–cyclin D complex and stopping cells at the G1 checkpoint.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038066073965,"sku":"pka-325-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038316323181,"sku":"pka-325-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038316355949,"sku":"pka-325-1MG","price":4800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cdk4-human-PKA-325.png?v=1782158163"},{"product_id":"recombinant-human-cyclin-dependent-kinase-5-sf9-bhp11000958","title":"Recombinant Human cyclin-dependent kinase 5, Sf9","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human cyclin-dependent kinase 5, Sf9\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCell division protein kinase 5 (CDK5) belongs to the cyclin-dependent kinase family. CDK5 is essential for appropriate development of the brain and in order to be activated CDK5 must link to CDK5R1 or CDK5R2. CDK5 doesn't need phosphorylation on the T loop so that binding with the activator is enough to activate the kinase. CDK5 is engaged in the processes of neuronal maturation and migration, phosphorylating the central intracellular adaptor of the reeling signaling chain.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"1 ug","offer_id":53038066106733,"sku":"pka-104-1UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"5 ug","offer_id":53038315340141,"sku":"pka-104-5UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53038315372909,"sku":"pka-104-50UG","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cdk5-protein-PKA-104.png?v=1782158162"},{"product_id":"recombinant-human-cyclin-dependent-kinase-2-sf9-bhp11000956","title":"Recombinant Human cyclin-dependent kinase 2, sf9","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human cyclin-dependent kinase 2, sf9\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCyclin-dependent kinase 2 (CDK2) belongs the Ser\/Thr protein kinase family. CDK2 is highly parallel to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. CDK2 is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is limited to the G1-S phase, and is vital for cell cycle G1\/S phase transition. The CDK2 protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). CDK2 activity is also regulated by protein phosphorylation.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038066139501,"sku":"pka-066-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038315536749,"sku":"pka-066-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038315569517,"sku":"pka-066-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cdk2-human-sf9-PKA-066.png?v=1782158162"},{"product_id":"recombinant-human-cyclin-i-bhp11000945","title":"Recombinant Human Cyclin-I","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Cyclin-I\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCCN1 is a part of the extremely conserved cyclin family, whose members are characterized by a remarkable periodicity in protein abundance through the cell cycle. Cyclins which function as regulators of CDK kinases, shows the highest similarity with cyclin G. Different cyclins display diverse expression and degradation patterns which contribute to the chronological coordination of every mitotic event. The transcript of CCN1was found to be expressed continually during cell cycle progression.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038066172269,"sku":"pka-318-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038313832813,"sku":"pka-318-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038313865581,"sku":"pka-318-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ccni-human-PKA-318.png?v=1782158162"},{"product_id":"recombinant-human-cyclin-dependent-kinase-inhibitor-2a-bhp11000962","title":"Recombinant Human Cyclin-Dependent Kinase Inhibitor 2A","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Cyclin-Dependent Kinase Inhibitor 2A\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCyclin-dependent kinase inhibitors (CDKIs) are proteins that bind to and inhibit the activity of CDKs. Two major classes of CDK inhibitors have been identified. The p16 family (p15, p16, p18 and p19) binds to and inhibits the activities of CDK4 and CDK6. The p21 family (p21, p27, p28 and p57) can bind to broad range of CDK-cyclin complexes and inhibit their activities. CDKIs are capable of suppressing growth, and several lines of evidence strongly suggest that at least some CDKIs may be tumor suppressor proteins.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038066237805,"sku":"pka-341-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038315471213,"sku":"pka-341-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038315503981,"sku":"pka-341-1MG","price":3510.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cdkn2a-human-PKA-341.png?v=1782158163"},{"product_id":"recombinant-human-cyclin-dependent-kinase-1-sf9-bhp11000955","title":"Recombinant Human cyclin-dependent kinase 1, sf9","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human cyclin-dependent kinase 1, sf9\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCyclin-dependent kinase 1 (CDK1) plays a significant part in the control of the eukaryotic cell cycle through modulating the centrosome cycle in addition to mitotic onset; CDK1 promotes G2-M transition and regulates G1 progress and G1-S transition using association with multiple interphase cyclins. CDK1 is essential in higher cells for the entry into S-phase and mitosis.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038066270573,"sku":"pka-065-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038314226029,"sku":"pka-065-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038314258797,"sku":"pka-065-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cdk1-human-sf9-PKA-065.png?v=1782158161"}],"url":"https:\/\/www.ebiohippo.com\/collections\/recombinant-protein-kinases-human.oembed?page=5","provider":"BioHippo","version":"1.0","type":"link"}