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Home / Biochemicals / Small Molecules

Acetyl Coenzyme A, Sodium salt

SKU : BHB21200004

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Mfr.No.	A-07, A-07-10MG, A-07-25MG, A-07-50MG, A-07-100MG
Description	Acetyl Coenzyme A (Acetyl-CoA) is a vital molecule in cellular metabolism, serving as a central intermediate in various biochemical processes. It is synthesized by the acetylation of Coenzyme A (CoA) through enzymatic reactions involving pyruvate dehydrogenase, ?-oxidation of fatty acids, and amino acid catabolism. The unique structure of Acetyl-CoA, with its reactive acetyl group, allows it to participate in numerous biochemical reactions, including the tricarboxylic acid (TCA) cycle, fatty acid synthesis, and cholesterol metabolism, making it an essential cofactor in cellular energy production and biosynthetic pathways (Pietrocola et al., 2015; Shi & Tu, 2015). Applications Acetyl Coenzyme A, Sodium Salt, is widely used in research to study cellular metabolism and enzyme functions, particularly those involving acetylation reactions. It is an important reagent for investigating metabolic pathways such as the TCA cycle, where Acetyl-CoA is a key substrate for citrate synthesis, and for studying fatty acid and cholesterol biosynthesis. Researchers utilize Acetyl-CoA Sodium Salt in in vitro assays to understand enzyme mechanisms, epigenetic modifications, and metabolic regulation in health and disease contexts (Pietrocola et al., 2015; Sibon & Strauss, 2016). Additionally, it plays a significant role in developing therapeutic strategies targeting metabolic diseases, cancer metabolism, and microbial infections (Spry et al., 2008).
Appearance	White to slight yellow
Molecular Formula	C23H35N7O17P3S · xNa
Synonyms	Acetyl-CoA
Shipping	Ambient temperature (styrofoam + ice gels)
Smiles	O=C(CCNC(C(C(C)(COP([O-])(OP([O-])(OCC(C(C1O)OP(O)([O-])=O)OC1N(C2=NC=N3)C=NC2=C3N)=O)=O)C)O)=O)NCCSC(C)=O.[Na+]
Cas Number	918149-33-4
Molecular Weight	809.57 g/mol (free acid basis)
Solubility	Soluble in water
Origin	Synthetic
Lead Time	In Stock
Notes	Research Use Only

Purity	≥ 95%
Form	Lyophilized powder
Storage	-20°C in a cool and dry place
Stability	≥ 2 years
Packaging	PP screw vials

Product Manual	Technical Specification MSDS

Reference	1. Pietrocola, F., Galluzzi, L., Bravo-San Pedro, J. M., Madeo, F., & Kroemer, G. (2015). Acetyl coenzyme A: A central metabolite and second messenger. Cell Metabolism, 21(6), 805-821. 2. Shi, L., & Tu, B. P. (2015). Acetyl-CoA and the regulation of metabolism: Mechanisms and consequences. Current Opinion in Cell Biology, 33, 125-131. 3. Sibon, O. C. M., & Strauss, E. (2016). Coenzyme A: To make it or uptake it? Nature Reviews Molecular Cell Biology, 17(10), 606-607. 4. Spry, C., Kirk, K., & Saliba, K. J. (2008). Coenzyme A biosynthesis: An antimicrobial drug target. FEMS Microbiology Reviews, 32(1), 56-106.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB21200004-1	A-07-10MG	10mg	$136.36		Add to Cart
BHB21200004-2	A-07-25MG	25mg	$284.09		Add to Cart
BHB21200004-3	A-07-50MG	50mg	$488.64		Add to Cart
BHB21200004-4	A-07-100MG	100mg	$863.64		Add to Cart

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