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Shanghai Model Organisms Center, Inc.
view supplier detailsCredit card payments now incur a 3% fee.
Shanghai Model Organisms Center, Inc.
view supplier detailsCredit card payments now incur a 3% fee.
| Mfr.No. | BHS19000005 |
| Service Type | Animal Model |
| Service Specification | Knock-in (KI), Point Mutation, Conditional Point Mutation, Humanization |
| Provider | GenoBioTX(SMOC) |
| Provider Location | Sugar Land, Texas, USA |
| Description | Accelerate your research with customized gene knockin mouse models that provide thorough insight into key genetic mechanisms.
Knock-in models include:
It usually takes 6-9 months to generate a conditional gene knockin mouse model by CRISPR gene editing technology. It usually takes 9-12 months to generate a conditional gene knockin mouse model by ES cell targeting technology. Shanghai Model Organisms Center (SMOC) has more than 6000 research-ready GEM models. Check out our website to find out whether your model of interest is available for direct purchase. Alternatively, you may contact our technical support staff to design a customized, gene knock-out model that fits your need best. Conventional gene knock-inSchematic of co-expression of exogenous genes: Schematic demonstration of replacing murine endogenous genes with exogenous DNA (i.e. knock-in and knockout simultaneously):  Point mutationIntroduction of point mutations into the corresponding positions of murine orthologous gene.
Tissue-specific point mutations can be achieved by inserting an expression cassette carrying the desired point mutation, which is flanked by the Cre-loxP element, into the corresponding positions of mouse orthologous gene. |
| Keywords/Tags | Customized Gene Knock-In,Mouse Models,Genetic Mechanisms,Genomic Loci,Gene Expression,Genetic Lineage,Humanized Mouse Model,Immunology-Oncology Research,Pre-Clinical Efficacy Evaluation, |
| Turnaround Time | 4-6 months, 6-9 months, 9-12 months |
| Geographic Availability | Global |
