Nkx2-5-IRES-Cre

Mfr.No.	NM-KI-200152
Description	Model Description: A IRES-Cre-WPRE-polyA expression cassette was knocked into the Nkx2-5 gene stop codon site. Official Symbol: Nkx2-5 NCBI ID link: 18091 MGI ID link: 97350 Ensembl ID link: ENSMUSG00000015579 Pubmed link: Nkx2-5 Human Ortholog: NKX2-5
Nomenclature	C57BL/6JSmoc-Nkx2-5^{em1(IRES-Cre-WPRE-polyA)Smoc}
Strain	Repository Live
KI/KO Gene	Nkx2-5
Synonyms	Csx, Nkx2.5, tinman, Nkx-2.5

Applications Range	Cre recombinase tool; Nkx2.5 acts as a key transcription factor and plays essential roles for heart formation. By mating the reporter mice with Cre-expressing mice, Nkx2-5 positive cells derived from double-positive mice were permanently labeled by fluorescent protein. When crossed with mice carrying a targeted floxed alleles, this strain is useful in eliminating tissue-specific conditional expression of the gene.
Research Application	Cre/Dre-Driver

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