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Home / Primary Antibodies / IHC Antibodies

Anti-ATF2 Antibody BHA11302318

SKU : BHA11302318

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Mfr.No.	BS4019
Alternative Names	Cyclic AMP-dependent transcription factor ATF-2 ; cAMP-dependent transcription factor ATF-2 ; Activating transcription factor 2 ; Cyclic AMP-responsive element-binding protein 2 ; CREB-2 ; cAMP-responsive element-binding protein 2 ; HB16 ; Histone acetyltransferase ATF2 ; cAMP response element-binding protein CRE-BP1 ; ATF-2 ; CREB2 ; CREBP1
Antigen	ATF2
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	2q31.1
Clonality	polyclonal
Description	The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways. Various forms of cellular stress, including genotoxic agents, inflammatory cytokines and UV irradiation, stimulate the transcriptional activity of ATF-2. Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71. Both SAPK and p38 MAPK have been shown to phosphorylate ATF-2 at these sites in vitro and in cells transfected with ATF-2.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human ATF2 around the phosphorylation site of Threonine 73.
Modification	phospho-T73
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P15336
Uniprot	P15336
Weight	55 to 75 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-ATF2 (T73) polyclonal antibody detects endogenous levels of ATF2 protein only when phosphorylated at Thr73.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC, IP

Description

IHC ; IP

Dilution

IHC	1:50-1:200
IP	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302318	BS4019	50µl	$199.33		Add to Cart
BHA11302318	BS4019	100µl	$314.89		Add to Cart

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