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Home / Primary Antibodies / Phospho Antibodies

Anti-CD19 Antibody BHA11302615

SKU : BHA11302615

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Mfr.No.	BS4664
Alternative Names	B-lymphocyte antigen CD19 ; B-lymphocyte surface antigen B4 ; Differentiation antigen CD19 ; T-cell surface antigen Leu-12
Antigen	CD19
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	16p11.2
Clonality	polyclonal
Description	CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is selectively expressed on the cell surface of B-lymphocytes, where it activates intracellular signaling cascades involving both Ras and phosphatidylinositol 3-kinase pathways. Activation of CD19 results in cross-linking of the membrane protein immunoglobulin chains and the subsequent association with Src family protein tyrosine kinases (PTK). Expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. CD19 forms functional complexes with B-lymphocyte surface proteins, including integrin β1, CD21 and CD81, which are involved in regulating B-cell development.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human CD19 around the phosphorylation site of Tyrosine 531.
Modification	phospho-Y531
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P15391
Uniprot	P15391
Weight	61, 95 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-CD19 (Y531) polyclonal antibody detects endogenous levels of CD19 protein only when phosphorylated at Tyr531.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302615	BS4664	50µl	$199.33		Add to Cart
BHA11302615	BS4664	100µl	$314.89		Add to Cart

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