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Home / Primary Antibodies / IHC Antibodies

Anti-CDH5 Antibody BHA11302508

SKU : BHA11302508

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Mfr.No.	BS4242
Alternative Names	Cadherin-5 ; 7B4 antigen ; Vascular endothelial cadherin ; VE-cadherin ; CD144 ; CDH5 ; Cadherin 5
Antigen	CDH5
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	16q21
Clonality	polyclonal
Description	The cadherins are a family of Ca 2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy-terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. VE-cadherin (for vascular endothelial cadherin, also designated cadherin-5) is localized at intercellular junctions of endothelial cells, where it is thought to play a role in the cohesion and organization of intercellular junctions.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human VE-Cadherin around the phosphorylation site of Tyrosine 731.
Modification	phospho-Y731
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P33151
Uniprot	P33151
Weight	130 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-VE-Cadherin (Y731) polyclonal antibody detects endogenous levels of VE-Cadherin protein only when phosphorylated at Tyr731
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302508	BS4242	50µl	$199.33		Add to Cart
BHA11302508	BS4242	100µl	$314.89		Add to Cart

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