Integrin alpha-M|CD11 antigen-like family member B|CR-3 alpha chain|Cell surface glycoprotein MAC-1 subunit alpha|Leukocyte adhesion receptor MO1|Neutrophil adherence receptor|CD11b|ITGAM|CD11B|CR3A|Integrin αM|CR-3α|CR3α
Integrin αM, also designated complement component receptor-3 α, CD11b (p170), macrophage antigen a polypeptide, cell surface glycoprotein Mac-1 a subunit, MAC1A, MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin αM combines with the Integrin β2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin αM/β2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
Homo Sapiens (Human)
Recombinant full length Human CD11B (630aa-1104aa).
Human, Mouse, Rat
Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.Specificity: CD11B (I1) polyclonal antibody detects endogenous levels of CD11B protein.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.