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Home / Primary Antibodies / Phospho Antibodies

Anti-HSP90AB1 Antibody BHA11302502

SKU : BHA11302502

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Mfr.No.	BS4235
Alternative Names	Heat shock protein HSP 90-beta ; HSP 90 ; Heat shock 84 kDa ; HSP 84 ; HSP84 ; HSP90AB1 ; HSP90B ; HSPC2 ; HSPCB
Antigen	HSP90AB1
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	6p21.1
Clonality	polyclonal
Description	HSP 90 family members guide the normal folding, intracellular disposition and proteolytic turnover of many key regulators of cell growth, differentiation and survival. HSP 90alpha, also designated HSP90A, HSP 86 and LPS-associated protein 2 (LAP2), is a cytosolic enhancer of inducible nitric-oxide synthase (iNOS), with chaperone activity that is important for the transcriptional activity of p53. HSP 90beta, also designated HSP90B, HSP 84 and HSPC2, is a cytosolic protein that participates in signaling pathways with PKC epsilon to protect cells from external damage, particularly in heat shock-mediated events. GRP 94, also known as tumor rejection antigen 1 (TRA1), ECGP and GP96, localizes to the ER, is highly expressed in BGC-823 human gastric carcinoma cells and is upregulated in human endothelial cells in response to hypoxia by HIF-1.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human HSP90B around the phosphorylation site of Serine 254.
Modification	phospho-S254
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P08238
Uniprot	P08238
Weight	90 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: HSP90B (phospho-S254) polyclonal antibody detects endogenous levels of HSP90B protein when phosphorylated at Ser254.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:1000-1:5000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302502	BS4235	50µl	$199.33		Add to Cart
BHA11302502	BS4235	100µl	$314.89		Add to Cart

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