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Home / Primary Antibodies / Phospho Antibodies

Anti-ITGB1 Antibody BHA11302597

SKU : BHA11302597

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Mfr.No.	BS4646
Alternative Names	Integrin beta-1 ; Fibronectin receptor subunit beta ; Glycoprotein IIa ; GPIIA ; VLA-4 subunit beta ; CD29 ; ITGB1 ; FNRB ; MDF2 ; MSK12
Antigen	ITGB1
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	10p11.22
Clonality	polyclonal
Description	Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands, such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human Integrin β1 around the phosphorylation site of Threonine 789.
Modification	phospho-T789
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P05556
Uniprot	P05556
Weight	90 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: p-Integrin β1 (T789) polyclonal antibody detects endogenous levels of Integrin β1 only when phosphorylated at Thr789.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302597	BS4646	50µl	$199.33		Add to Cart
BHA11302597	BS4646	100µl	$314.89		Add to Cart

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