Anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Antibody BHA10203024

Mfr.No.	3973-MSM3-P0
Alternative Names	Gonadotropin receptor ; GTHR-II ; HHG ; LCGR ; LGR2 ; LH-R ; LH/CG-R ; LH/CGR ; LHCGR ; LHR
Antigen	Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR)
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic
Chromosome Location	2p21
Clonality	Monoclonal
Conjugate	Unconjugated
Description	Recognizes a protein of 78-85kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
Host	Mouse
Immunogen	Recombinant N-terminal fragment of human LHCGR (exact sequence is proprietary)
Isotype	IgG1 Kappa
Positive Control	HepG2 or Jurkat cells. Ovarian Carcinoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P22888
Uniprot	468490
Gene Id	3973

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	200µg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab with BSA and Azide at 200μg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml
IHC-F	0.5-1μg/ml for 30 min at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10203024	3973-MSM3-P0	20µg	$204.67		Add to Cart
BHA10203024	3973-MSM3-P0	100µg	$393.20		Add to Cart

Anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Antibody BHA10203024

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