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Home / Primary Antibodies / IHC Antibodies

Anti-MAPK10/MAPK9/MAPK8 Antibody BHA11300701

SKU : BHA11300701

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Mfr.No.	BS1544
Alternative Names	JNK 46 ; JNK 55 ; JNK ; JNK1 ; JNK1A2 ; JNK2 ; JNK21B1/2 ; JNK2ALPHA ; JNK2B ; JNK2BETA ; JNK3 ; JNK3A ; MAP kinase 8 ; MAP kinase 9 ; MAP kinase p49 3F12 ; MAPK 8 ; MAPK 9 ; MAPK10 ; MAPK8 ; MAPK9 ; MGC50974 ; Mitogen activated protein kinase 10 ; Mitogen activated protein kinase 8 ; Mitogen activated protein kinase 9
Antigen	MAPK10/MAPK9/MAPK8
Categories	Primary Antibodies
Clonality	polyclonal
Description	The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in Ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun and other signaling kinases, including MEKK1 and p38. JNK3 (MK10, MAPK10, PRKM10) is activated by pro-inflammatory cytokines and environmental stresss by phosphorylating transcription factors such as c-Jun and ATF2. This is important for AP-1 transcriptional activity regulation. JNK3 is crucial for neuronal apoptosis (stress-induced).
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 150-200 of Human JNK1.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P45983/P45984/P53779
Uniprot	P45983/P45984/P53779
Weight	46,54 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: JNK1/2/3 (T178) polyclonal antibody detects endogenous levels of JNK1/2/3 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300701	BS1544	50µl	$190.44		Add to Cart
BHA11300701	BS1544	100µl	$294.44		Add to Cart

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