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Home / Primary Antibodies / IHC Antibodies

Anti-MARCKS Antibody BHA11302719

SKU : BHA11302719

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Mfr.No.	BS4799
Alternative Names	Myristoylated alanine-rich C-kinase substrate ; MARCKS ; Protein kinase C substrate, 80 kDa protein, light chain ; 80K-L protein ; PKCSL ; MARCKS ; MACS ; PRKCSL
Antigen	MARCKS
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	6q21
Clonality	polyclonal
Description	Myristoylated alanine-rich protein kinase C substrate (MARCKS), also designated 80K or 80K-L, has been identified as a major cellular substrate for protein kinase C. Human MARCKS is a 332 amino acid protein with a calculated molecular weight of 31.534 kDa; however, it has been shown to run at 80-87 kDa on Western blot. The plasma membrane bound protein dissociates from the membrane upon phosphorylation by various PKC isoforms. In NIH/3T3 fibroblasts, PKC α and PKC ε, but not PKC δ, are responsible for MARCKS phosphorylation. MARCKS has been found to bind calmodulin, Actin and Synapsin and is a filamentous (F) Actin crosslinking protein.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human MARCKS around the phosphorylation site of Serine 163.
Modification	phospho-S163
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P29966
Uniprot	P29966
Weight	32, 75, 87 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: p-MARCKS (S163) polyclonal antibody detects endogenous levels of MARCKS only when phosphorylated at Ser163.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302719	BS4799	50µl	$199.33		Add to Cart
BHA11302719	BS4799	100µl	$314.89		Add to Cart

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