NEK 9|Nek8|nek9|NEK9|Nercc 1 kinase|NERCC|NERCC1|Nercc1 kinase|Never in mitosis A related kinase 9|Never in mitosis A-related kinase 9|NIMA (never in mitosis gene a) related kinase 9|NIMA related kinase 8|NIMA related kinase 9|NIMA related kinase Nek8|NimA related protein kinase 9|NIMA-related kinase 8|NimA-related protein kinase 9|Serine/threonine protein kinase Nek9|Serine/threonine-protein kinase Nek9
Nek9 [NIMA (never in mitosis gene a)- related kinase 9], also known as serine/threonine-protein kinase Nek9, NERCC, NERCC1, MGC16714, MGC138306 or DKFZp434D0935, is a 979 amino acid protein that localizes to cytoplasm and nucleus. Highly expressed in liver, heart, kidney and testis, Nek9 is also expressed at lower levels in fibroblasts and smooth muscle cells. Nek9 regulates G1/S transition and S phase progression by influencing spindle dynamics and chromosome separation. Nek9 phosphorylates different histones (Histone H3 on serine and threonine), myelin basic protein, beta-casein (serine) and BICD2. Nek9 interacts with Ran GTPase, Nek6, Nek7, BICD2, SSRP1 and SUPT16H/FACT complex.
Homo Sapiens (Human)
Synthetic peptide, corresponding to amino acids 170-220 of Human Nek9.
Human, Mouse, Rat
Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: Nek9 (S206) polyclonal antibody detects endogenous levels of Nek9 protein.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.