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Home / Primary Antibodies / Phospho Antibodies

Anti-PRKCA Antibody BHA11302557

SKU : BHA11302557

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Mfr.No.	BS4346
Alternative Names	Protein kinase C alpha type ; PKC-A ; PKC-alpha ; PRKCA ; PKCA ; PRKACA
Antigen	PRKCA
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	17q24.2
Clonality	polyclonal
Description	Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (α, βI, βII and γ) and novel (n) PKC isoforms (δ, ε, ζ, η and θ). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC δ and ε are independent of Ca2+.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human PKC α around the phosphorylation site of Threonine 638.
Modification	phospho-T638
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P17252
Uniprot	P17252
Weight	80 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: p-PKC á/â2 (T638) polyclonal antibody detects endogenous levels of PKC á/â2 protein when phosphorylated at Thr638.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302557	BS4346	50µl	$199.33		Add to Cart
BHA11302557	BS4346	100µl	$314.89		Add to Cart

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