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Home / Primary Antibodies / Phospho Antibodies

Anti-SSB Antibody BHA11300055

SKU : BHA11300055

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Mfr.No.	AP0349
Alternative Names	Autoantigen La ; La ; La autoantigen ; La autoantigen homolog ; La protein ; La ribonucleoprotein ; La ribonucleoprotein domain family member 3 ; LA ; LARP3 ; Lupus La antigen ; Lupus La protein ; Lupus La protein homolog ; mRNA for autoantigen ; Sjoegren syndrome type B antigen ; Sjoegren syndrome type B antigen ; Sjogren syndrome antigen B ; SS B ; SS-B ; SS-B/La protein ; SSB
Antigen	SSB
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	2q31.1
Clonality	polyclonal
Description	Ro/SSA is a ribonucleoprotein that binds to autoantibodies in 35 to 50% of patients with SLE and in up to 97% of patients with Sjogren syndrome. The Ro/SSA particle consists of a single immunoreactive protein noncovalently bound with one of four small RNA molecules. Most anti-Ro/SSA-positive sera have antibodies not only against the immunoreactive protein, but also against an Ro/SSA protein. The genes which encode the two proteins map to human chromosomes 11p15.5 and 1q31, respectively. La/SSB is an autoimmune RNA-binding protein that plays a role in the transcription of RNA polymerase III was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and SLE.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human SSB around the phosphorylation site of Serine 366.
Modification	phospho-S366
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P05455
Uniprot	P05455
Weight	52 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: p-SSB (S366) polyclonal antibody detects endogenous levels of SSB protein only when phosphorylated at Serine 366.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 110% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:1000-1:2000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300055	AP0349	50µl	$199.33		Add to Cart
BHA11300055	AP0349	100µl	$314.89		Add to Cart

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