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Home / Primary Antibodies / Phospho Antibodies

Anti-SYK Antibody BHA11302470

SKU : BHA11302470

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Mfr.No.	BS4188
Alternative Names	Tyrosine-protein kinase SYK ; Spleen tyrosine kinase ; p72-Syk ; SYK
Antigen	Syk
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	9q22.2
Clonality	polyclonal
Description	Syk (spleen tyrosine kinase) is a 635 amino acid protein that contains one protein kinase domain and two SH2 domains. One of several members of the protein kinase superfamily, Syk functions as a positive effector of B cell antigen receptor (CD79)-stimulated responses, coupling CD79 with the movement of one calcium ion through one of two phospho-regulated pathways. Via its ability to influence CD79 activity and to control the movement of calicum through the cell, Syk plays an important role in a variety of cellular responses, including differentiation, phagocytosis, proliferation and B cell development. Syk expression is upregulated in T cell lymphoma, suggesting a possible role for Syk in tumorigenesis. Two isoforms of Syk, designated short and long, exist due to alternative splicing events.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human Syk around the phosphorylation site of Tyrosine 348.
Modification	phospho-Y348
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P43405
Uniprot	P43405
Weight	72 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-Syk (Y348) polyclonal antibody detects endogenous levels of Syk protein only when phosphorylated at Tyr348.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC

Description

IHC

Dilution

IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302470	BS4188	50µl	$199.33		Add to Cart
BHA11302470	BS4188	100µl	$314.89		Add to Cart

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