Anti-undefined Antibody CCNE1,2460 Unconjugated BHA10207913

Mfr.No.	898-MSM1-P0
Alternative Names	CCNE1 ; Cyclin E1 ; G1/S-specific cyclin-E1
Antigen	Cyclin E (G1/S-Phase Cyclin)
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	19q12
Clonality	monoclonal
Conjugate	Unconjugated
Description	Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.
Host	Mouse
Immunogen	Recombinant fragment of human Cyclin E (CCNE1) protein (around aa 10-176) (exact sequence is proprietary)
Isotype	IgG2b Kappa
Positive Control	HeLa Cells. Breast or Colon Carcinoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	IDP24864
Gene Id	898
Clone No	CCNE1, 2460
Symbol	CCNE1
Weight	53kDa

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	200μg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab with BSA and Azide at 200μg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

IHC-F

Description

Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., IHC-F

Dilution

Immunohistology (Formalin-fixed)

1-2μg/ml for 30 min at RT

No Description Available.

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10207913	898-MSM1-P0	20µg	$204.67		Add to Cart
BHA10207913	898-MSM1-P0	100µg	$393.20		Add to Cart

Anti-undefined Antibody CCNE1,2460 Unconjugated BHA10207913

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