Rabbit Anti-Human Alpha Synuclein (pTyr136) Polyclonal

Mfr.No.	SPC-1435, SPC-1435D, SPC-1435D-A390, SPC-1435D-A488, SPC-1435D-A594, SPC-1435D-BI, SPC-1435D-FITC
Immunogen Species	Human
Alternative Names	Alpha Synuclein Antibody, Non-A4 component of amyloid precursor Antibody, MGC105443 Antibody, OTTHUMP00000218552 Antibody, MGC110988 Antibody, OTTHUMP00000218553 Antibody, Synuclein alpha 140 Antibody, alphaSYN Antibody, Parkinson disease familial 1 Antibody, OTTHUMP00000218554 Antibody, Parkinson disease (autosomal dominant, Lewy body) 4 Antibody, Synuclein, alpha (non A4 component of amyloid precursor) Antibody, OTTHUMP00000218549 Antibody, Non A4 component of amyloid precursor Antibody, MGC127560 Antibody, SYN Antibody, SNCA Antibody, MGC64356 Antibody, Non A4 component of amyloid Antibody, PARK4 Antibody, Alpha synuclein Antibody, PARK 1 Antibody, Snca synuclein, Synuclein alpha Antibody, Non-A4 component of amyloid, precursor of Antibody, OTTHUMP00000218551 Antibody, PARK 4 Antibody, PARK1 Antibody, Alpha-synuclein, isoform NACP140 Antibody, Non-A-beta component of alzheimers disease amyloid, Non-A beta component of AD amyloid Antibody, NACP Antibody, SYUA_HUMAN Antibody, Alpha-synuclein Antibody, Non A beta component of AD amyloid Antibody
Antigen	Alpha Synuclein
Categories	Antibodies
Cellular Localization	Cytoskeleton, Endoplasmic Reticulum, Extracellular Space, Cytosol, Nucleus, Secreted, Membrane Synapse, Membrane, Synapse, Actin Cytoskeleton, Rough Endoplasmic Reticulum, Extracellular Region, Golgi Apparatus, Lysosome, Mitochondrion, Nuclear Outer Membrane, Plasma Membrane, Axon, Cell Cortex, Cell Junction, Cytoplasm, Cytoplasmic Vesicle Membrane, Growth Cone, Inclusion Body, Neuronal Cell Body, Perinuclear Region Of Cytoplasm, Postsynapse, Ribosome, Supramolecular Fiber, Synaptic Vesicle, Terminal Bouton
Clonality	Polyclonal
Conjugate	Unconjugated, ATTO 390, ATTO 488, ATTO 594, Biotin, FITC
Description	Rabbit Anti-Human Alpha Synuclein (pTyr136) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Synthetic phospho-peptide from human Alpha Synuclein around the phosphorylation site of tyrosine 136 (pTyr136)., Homo Sapiens (Human)
Immunogen Region	Synthetic phospho-peptide from human Alpha Synuclein around the phosphorylation site of tyrosine 136 (pTyr136).
Isotype	IgG
Launch Date	2018/03/07
Net Weight (g)	0.1
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Mouse, Rat, Human
Tissue Specificity	Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.

Swissprot	P37840
Accession Number	NP_000336.1
Gene Id	6622
Target	Alpha Synuclein (pTyr136)
Research Area	Tangles & Tau, Multiple System Atrophy, Neurodegeneration, Alzheimer's Disease, Parkinson's Disease, Synuclein, Neuroscience

Buffer	PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide
Dilutions	WB (1:250-1:1000); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.
Scientific Background	Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects endogenous levels of Alpha Synuclein only when phosphorylated at tyrosine 136 (pTyr136). Detects a band at ~18 kDa.
Storage	-20ºC
Storage Buffer	PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	WB
Description	WB
Dilution	WB (1:250-1:1000); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11920016-1	SPC-1435D	Unconjugated	100 ul	$331	Add to Cart
BHA11920016-2	SPC-1435D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11920016-3	SPC-1435D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11920016-4	SPC-1435D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11920016-5	SPC-1435D-BI	Biotin	100 ul	$380	Add to Cart
BHA11920016-6	SPC-1435D-FITC	FITC	100 ul	$375	Add to Cart

Alpha Synuclein Antibody (pTyr136) - SPC-1435

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