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Home / Antibodies

Anti-CLDN11 Antibody BHA11300247

SKU : BHA11300247

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Mfr.No.	BS1065
Alternative Names	CLDN11 ; CLAUDIN-11 ; OSP ; OTM ; Claudin 11 ; Claudin11
Antigen	CLDN11
Categories	Primary Antibodies
Chromosome Location	3q26.2
Clonality	polyclonal
Description	The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteinsare known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 171-220 of Human Claudin-11.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O75508
Uniprot	O75508
Weight	24 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Claudin 11 (S198) polyclonal antibody detects endogenous levels of Claudin 11 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300247	BS1065	50µl	$190.44		Add to Cart
BHA11300247	BS1065	100µl	$294.44		Add to Cart

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