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Home / Primary Antibodies / IHC Antibodies

Anti-SNCA Antibody BHA11300750

SKU : BHA11300750

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Mfr.No.	BS1596
Alternative Names	Alpha-synuclein ; α-synuclein ; Non-A beta component of AD amyloid ; Non-A4 component of amyloid precursor ; NACP ; SNCA ; NACP ; PARK1
Antigen	SNCA
Categories	Primary Antibodies
Chromosome Location	4q22.1
Clonality	polyclonal
Description	The synuclein family members, including α-synuclein (also designated NACP for non-β amyloid component) and β-synuclein, are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. α-synuclein is localized to neuronal cell bodies and synapses. α-synuclein was first identified as a component of Alzheimer’s disease amyloid plaques. Abnormal platelet function in Alzheimer’s disease has been demonstrated. During megakaryocytic differentiation α-synuclein was found to be up-regulated, while β-synuclein is down-regulated, indicating that coordinate expression of synucleins may be important during hematopoetic cell differentiation. A mutant form of α-synuclein has been found in patients with early onset Parkinson’s disease.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 100-150 of Human Synuclein-α.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P37840
Uniprot	P37840
Weight	18 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Synuclein-α (E123) polyclonal antibody detects endogenous levels of Synuclein-α protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC

Description

IHC

Dilution

IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300750	BS1596	50µl	$190.44		Add to Cart
BHA11300750	BS1596	100µl	$294.44		Add to Cart

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