Rabbit Anti-Human GSK3a (pTyr284 + pTyr285) Polyclonal

Mfr.No.	SPC-990, SPC-990D, SPC-990D-A390, SPC-990D-A488, SPC-990D-A594, SPC-990D-BI, SPC-990D-FITC
Immunogen Species	Human
Alternative Names	DKFZp686D0638 Antibody, Glycogen synthase kinase 3 alpha Antibody, GSK3 alpha Antibody, Serine/threonine protein kinase GSK3A Antibody
Antigen	GSK3a
Categories	Antibodies
Cellular Localization	Beta-catenin Destruction Complex, Cytosol
Certificate Of Analysis	A 1:250 dilution of SPC-990 was sufficient for detection of GSK3a (pTyr284 + pTyr285) in 10 ug of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Conjugate	Unconjugated, ATTO 390, ATTO 488, ATTO 594, Biotin, FITC
Description	Rabbit Anti-Human GSK3a (pTyr284 + pTyr285) Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	A phospho-specific peptide corresponding to residues surrounding Tyr284 and Tyr285 of human GSK3a (AA282-288), Homo Sapiens (Human)
Immunogen Region	A phospho-specific peptide corresponding to residues surrounding Tyr284 and Tyr285 of human GSK3a (AA282-288)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Human

Swissprot	P49840
Accession Number	NP_063937
Gene Id	2931
Target	GSK3a (pTyr284 + pTyr285)
Research Area	Hypertrophy \|Apoptosis, Cell Signaling, Protein Phosphorylation, Cdks, Serine / Threonine Kinases, Stem Cells, Signaling Pathways, Wnt / Beta Catenin Pathway, Cardiovascular System, Heart

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Scientific Background	GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 50.981 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11912636-1	SPC-990D	Unconjugated	100 ul	$331	Add to Cart
BHA11912636-2	SPC-990D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11912636-3	SPC-990D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11912636-4	SPC-990D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11912636-5	SPC-990D-BI	Biotin	100 ul	$380	Add to Cart
BHA11912636-6	SPC-990D-FITC	FITC	100 ul	$375	Add to Cart

GSK3a Antibody (pTyr284 + pTyr285) - SPC-990