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Home / Antibodies

MAVS Antibody (IPS-1) (F43253)

SKU : BHA17100604

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NSJ Bioreagents

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Mfr.No.	F43253, F43253-0.08ML, F43253-0.4ML
Antigen	MAVS
Clonality	Polyclonal
Description	Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 or by the cytoplasmic RNA helicases MDA5 and RIGI. These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA and IKKB which activate NFKB, or TBK1 and IKKE (IKBKE; MIM 605048), which activate IRF3. Activated IRF3 and NFKB induce transcription of IFNB. For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF. For RIGI, the intermediary protein is mitochondria-bound IPS1.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 477-505 from the human protein was used as the immunogen for this MAVS antibody.
Isotype	Ig
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	Q7Z434

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	Aliquot the MAVS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, ELISA
Dilution	Western blot: 1:1000

Product Manual	Data Sheet

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17100604-1	F43253-0.08ML	0.08ml	$165		Add to Cart
BHA17100604-2	F43253-0.4ML	0.4ml	$379		Add to Cart

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