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Home / Primary Antibodies / Polyclonal Antibodies

NLRP2 antibody

SKU : BHA10805750

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Mfr.No.	FNab05758
Alternative Names	NALP2 ; NBS1 ; PAN1 ; PYPAF2
Background	Suppresses TNF-and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
Host	Rabbit
Immunogen	NLR family, pyrin domain containing 2
Isotype	IgG
Molecular Weight	105-110 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	NALP2, NBS1, PAN1, PYPAF2

Antigen	NLRP2
Uniprot	Q9NX02
Gene Id	55655
Research Area	Immunology

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805750	FNab05758	100ug	$280		Add to Cart

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