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Home / Primary Antibodies / Conjugated Primary Antibodies

PCBP2 Antibody, FITC conjugated

SKU : BHA10531330

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA622995LC01HU
Alternative Names	Poly(rC)-binding protein 2 (Alpha-CP2) (Heterogeneous nuclear ribonucleoprotein E2) (hnRNP E2), PCBP2
Antigen	PCBP2
Categories	Primary Antibodies
Clonality	polyclonal
Conjugate	FITC
Description	Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:19881509). It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:19881509).
Host	Rabbit
Immunogen	Recombinant Human Poly(rC)-binding protein 2 protein (171-293AA)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:19881509). It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:19881509).
Species	Homo Sapiens (Human)
Subcellular Location	Nucleus, Cytoplasm

Uniprot	Q15366
Database Links	HGNC:8648 OMIM:601210 KEGG:hsa:5094 STRING:9606.ENSP00000352438 UniGene:Hs.546271
Function	Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling
Research Area	Microbiology
Tissue Specificity	Detected in all tissues examined.

Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Format	Liquid
Purification	>95%, Protein G purified
Purity	>95%,Protein G purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Applications	ELISA
Description	ELISA
Tested Application	ELISA

Datasheet
ELISA Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10531330	CSB-PA622995LC01HU	100ug	$299		Add to Cart
BHA10531330	CSB-PA622995LC01HU	50ug	$166		Add to Cart

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