ELISA Kit for Rat B-cell lymphoma/leukemia 10

Mfr.No.	E9627r
Antigen	BCL10
Alternative Names	B-cell CLL/lymphoma 10 ; Bcl-10 ; R-RCD1 ; RCD
Categories	Elisa
Function	Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex (By similarity). Is a substrate for MALT1.
Specificity	Natural and recombinant Rat B-cell lymphoma/leukemia 10
Subcellular Location	Cytoplasm Membrane raft Colocalized with DPP4 in membrane rafts.
Detection Range	0.156-10ng/mL
Entryname	BCL10_RAT
Method Type	Sandwich
Platform	PF00619
Protein Name	B-cell lymphoma/leukemia 10
Sensitivity	0.085ng/mL
Sequence	50: MEAPAPSLTE ; EDLTEVKKDA ; LENLRVYLCE ; KIIAERHFDH ; LRAKKILSRE ; 100: DTEEISCRTS ; SRKRAGKLLD ; YLQENPKGLD ; TLVESIRREK ; TQNFLIQKIT ; 150: DEVLKLRNIK ; LEHLKGLKCS ; SCEPFAAGAT ; NNLSRSNSDE ; SNFSEKQRPS ; 200: TVIYHPEGES ; STAPFFSTES ; SLNLPVLEVG ; RLENSSFSSA ; SLPRPGDPGA ; 233: PPLPPDLRLE ; EGGSCGNSSE ; MFLPLRSRAL ; SRQ
Sequence Length	233
String	Q9QYN5
Sub Unit	Found in a membrane raft complex, at least composed of BCL10, CARD11, DPP4 and IKBKB. Self-associates by CARD-CARD interaction and interacts with other CARD-proteins such as CARD9, CARD10, CARD11 and CARD14. Binds caspase-9 with its C-terminal domain (By similarity). Interacts with TRAF2 and BIRC2/c-IAP2.

Reference	1. "Regulatory mechanisms of TRAF2-mediated signal transduction by Bcl10, a MALT lymphoma-associated protein." Yoneda T., Imaizumi K., Maeda M., Yui D., Manabe T., Katayama T., Sato N., Gomi F., Morihara T., Mori Y., Miyoshi K., Hitomi J., Ugawa S., Yamada S., Okabe M., Tohyama M. J. Biol. Chem.275:11114-11120(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Embryonic brain. 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Prostate.

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BHE13801227	E9627r	96T	$796		Add to Cart