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Home / Biochemicals / Small Molecules

(RS)-AMPA

SKU : BHB21300013

An Agonist of AMPA Receptors

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Alomone Labs

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Mfr.No.	A-265, A-265_10 mg, A-265_25 mg, A-265_5 mg, A-265_50 mg
Description	(RS)-AMPA (#A-265) is a highly pure, synthetic, and biologically active compound.
Molecular Formula	C7H10N2O4.
Synonyms	Synthetic
Background	Glutamate is the main excitatory neurotransmitter in the CNS. It is also involved in a variety of pathological conditions including epilepsy. Glutamate binds to a number of different receptor types such as the AMPA, kainate and NMDA receptors that relay its excitatory activity.(RS)-AMPA is a synthetic AMPA receptor agonist. It has an effective concentration of 0.1-100 uM. RS-AMPA selectively binds to AMPA receptors over the other types of glutamate receptors. RS-AMPA was found to elicit feeding behavior in a rat model while RS-AMPA's enantiomer did not produce similar results1.
Shipping	Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C
Concentration	0.1-100 uM.
Reconstitution	10 mM in H2O. Centrifuge all product preparations before use (10,000 x g for 1 min).
Cas Number	74341-63-2
Molecular Weight	186.16
Solubility	10 mM in H2O. Centrifuge all product preparations before use (10,000 x g for 1 min).
Target	AMPA receptors
Activity	(RS)-AMPA is a selective AMPA receptor agonist1.
Country Of Origin	Israel/IL
UNSPSC Code	41116134
Application	FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay
Lead Time	1-2 Business Days
Notes	Bioassay Tested: Yes Cited Application: Electrophysiology Chemical Name: 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid.

Purity	>99% (HPLC)
Form	Lyophilized powder.
Storage	Storage After Reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles. Storage of solutions: Up to four weeks at 4°C or three months at -20°C.

Product Manual	SDS

Reference	Howes, J.F. and Bell, C. (2007) Neurotherapeutics 4, 126. Traynelis, S.F. et al. (2010) Pharmacol. Rev. 62, 405.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB21300013-1	A-265_10 mg	10 mg	$151		Add to Cart
BHB21300013-2	A-265_25 mg	25 mg	$337		Add to Cart
BHB21300013-3	A-265_5 mg	5 mg	$117		Add to Cart
BHB21300013-4	A-265_50 mg	50 mg	$611		Add to Cart

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