AKB-6899

Mfr.No.	T29797
Description	AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages. AKB-6899 leads to stabilization of HIF-2alpha which induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth.
Alternative Names	AKB 6899
Molecular Formula	C14H11FN2O4
Signaling Pathways	Angiogenesis, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Metabolism
Smiles	OC1=CC(=CN=C1C(NCC(O)=O)=O)C2=CC(F)=CC=C2
Cas Number	1007377-55-0
Molecular Weight	290.25
Target	VEGFR, HIF, HIF/HIF Prolyl-Hydroxylase

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SKU	Supplier No.	Size	Your price
BHB20419531	T29797	1 mL	$197	Add to Cart
BHB20419531	T29797	1 mg	$74	Add to Cart
BHB20419531	T29797	5 mg	$178	Add to Cart
BHB20419531	T29797	10 mg	$288	Add to Cart
BHB20419531	T29797	25 mg	$485	Add to Cart
BHB20419531	T29797	50 mg	$693	Add to Cart
BHB20419531	T29797	100 mg	$987	Add to Cart