Ciglitazone

Mfr.No.	T19710
Description	Ciglitazone (ADD 3878) is a potent and selective PPARgamma agonist (EC50: 3 uM) and oral hypoglycemic agent. Ciglitazone inhibits proliferation and differentiation of th17 cells, decreases insulin levels, vascular endothelial growth factor production and blood pressure, and induces cell cycle arrest in gastric cancer cells. Selegiline induces apoptosis in opossum kidney epithelial cells and activates nuclear translocation of p38 MAPK and apoptosis-inducing factor (AIF). Ciglitazone exhibits hypoglycaemic activity in animal models of obesity and hyperglycaemia.
Alternative Names	ADD 3878
Molecular Formula	C18H23NO3S
Signaling Pathways	Apoptosis, Metabolism, DNA Damage/DNA Repair, MAPK
Smiles	C(C1SC(=O)NC1=O)C2=CC=C(OCC3(C)CCCCC3)C=C2
Cas Number	74772-77-3
Molecular Weight	333.45
Target	Apoptosis, p38 MAPK, PPAR

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SKU	Supplier No.	Size	Your price	Quantity
BHB20410349	T19710	5 mg	$91		Add to Cart