GSK-J4

Mfr.No.	T3100
Description	GSK-J4 (GSK J4 HCl) is a potent H3K27me3 demethylase inhibitor, with IC50s of 8.6 uM and 6.6 uM towards KDM6B and KDM6A respectively. It is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM in a cell-free assay and inactive against a panel of demethylases of the JMJ family.
Alternative Names	GSK J4
Molecular Formula	C24H27N5O2
Signaling Pathways	Apoptosis, Chromatin/Epigenetic
Smiles	N(CCC(OCC)=O)C1=CC(=NC(=N1)C2=CC=CC=N2)N3CCC=4C(CC3)=CC=CC4
Cas Number	1373423-53-0
Molecular Weight	417.5
Target	Histone Demethylase, Apoptosis

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SKU	Supplier No.	Size	Your price
BHB20420692	T3100	1 mL	$144	Add to Cart
BHB20420692	T3100	2 mg	$51	Add to Cart
BHB20420692	T3100	5 mg	$83	Add to Cart
BHB20420692	T3100	10 mg	$131	Add to Cart
BHB20420692	T3100	25 mg	$239	Add to Cart
BHB20420692	T3100	50 mg	$384	Add to Cart
BHB20420692	T3100	100 mg	$582	Add to Cart
BHB20420692	T3100	200 mg	$737	Add to Cart