Pifithrin-? hydrobromide

Mfr.No.	T3637
Description	Pifithrin-beta hydrobromide (Cyclic PFT-alpha) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of Y therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 uM).
Alternative Names	PFT beta (hydrobromide)
Molecular Formula	C16H17BrN2S
Signaling Pathways	Apoptosis
Smiles	Cc1ccc(cc1)c1cn2c3c(CCCC3)sc2n1.Br
Cas Number	511296-88-1
Molecular Weight	349.29
Target	p53, Ferroptosis

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SKU	Supplier No.	Size	Your price
BHB20425678	T3637	1 mL	$53	Add to Cart
BHB20425678	T3637	2 mg	$34	Add to Cart
BHB20425678	T3637	5 mg	$51	Add to Cart
BHB20425678	T3637	10 mg	$85	Add to Cart
BHB20425678	T3637	25 mg	$153	Add to Cart
BHB20425678	T3637	50 mg	$223	Add to Cart
BHB20425678	T3637	100 mg	$332	Add to Cart