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Home / Primary Antibodies / Recombinant Antibodies

Anti-RNF40 Antibody BHA11308126

SKU : BHA11308126

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Mfr.No.	BS8221
Alternative Names	E3 ubiquitin-protein ligase BRE1B ; BRE1-B ; 95 kDa retinoblastoma-associated protein ; RBP95 ; RING finger protein 40 ; RNF40 ; BRE1B ; KIAA0661
Antigen	RNF40
Categories	Primary Antibodies
Chromosome Location	16p11.2
Clonality	polyclonal
Description	Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). RNF40 (RING finger protein 40), also known as BRE1B, Staring or RBP95, is a 1,001 amino acid nuclear protein that contains one RING-type zinc finger. Expressed ubiquitously with highest expression in heart, testis and pancreas, RNF40 functions as an E3 ubiquitin-protein ligase that regulates the monoubiquitination and subsequent degradation of select residues on target proteins, such as Histone H2B and Syntaxin 1. In addition, RNF40 forms a ubiquitin ligase complex with UBCH6 (an E2 enzyme) and together, these proteins play a crucial role in regulation of the histone code. Four isoforms of RNF40 exist due to alternative splicing events.
Host	Rabbit
Immunogen	Recombinant full length Human RNF40.
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O75150
Uniprot	O75150
Weight	114 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: RNF40 polyclonal antibody detects endogenous levels of RNF40 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF, ChIP

Description

WB ; IHC ; IF ; ChIP

Dilution

WB	1:500-1:2000
IHC	1:50-1:200
IF	1:20-1:100
ChIP	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308126	BS8221	50µl	$234.89		Add to Cart
BHA11308126	BS8221	100µl	$368.22		Add to Cart

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