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Home / Biochemicals / Small Molecules

Coenzyme A, Sodium salt

SKU : BHB21200017

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Mfr.No.	A-17, A-17-10MG, A-17-25MG, A-17-50MG, A-17-100MG
Description	Coenzyme A (CoA) is an indispensable and ubiquitous metabolic cofactor for all organisms. It is synthesized in an evolutionarily conserved pathway by enzymatic conjugation of cysteine, pantothenate (Vitamin B5), and ATP. This unique chemical structure allows CoA to employ its highly reactive thiol group for diverse biochemical reactions. CoA is involved in approximately 9% of all metabolic pathways, including the tricarboxylic acid (TCA) cycle, fatty acid regulation, amino acid synthesis, and lipid metabolism (Leonardi et al., 2005; Daugherty et al., 2002). Applications Coenzyme A Sodium Salt is widely used in metabolic research and biochemical studies due to its critical role in various enzymatic reactions and metabolic pathways. It is particularly valuable for investigating the mechanisms of energy production, lipid metabolism, and biosynthesis of key cellular components. Researchers utilize CoA Sodium Salt in studies related to cellular signaling, redox regulation, and metabolic diseases to understand better CoA's regulatory functions and its potential as a therapeutic target (Leonardi et al., 2005; Sibon & Strauss, 2016). Furthermore, its role in fatty acid oxidation and synthesis makes it a crucial reagent in developing treatments for metabolic disorders and understanding microbial metabolism (Spry et al., 2008).
Appearance	White to slight yellow
Molecular Formula	C21H33N7O16P3S · xNa · yH2O
Synonyms	CoA Na2
Shipping	Ambient temperature (styrofoam + ice gels)
Smiles	SCCNC(CCNC(C(C(C)(COP([O-])(OP([O-])(OCC(C(C1O)OP(O)([O-])=O)OC1N(C2=NC=N3)C=NC2=C3N)=O)=O)C)O)=O)=O.[Na+]
Cas Number	55672-92-9
Molecular Weight	767.53 g/mol (anhydrous free acid basis)
Solubility	Soluble in water
Origin	Biosynthetic
Lead Time	In Stock
Notes	Research Use Only

Purity	≥ 98%
Form	Lyophilized powder
Storage	-20°C in a cool and dry place
Stability	≥ 2 years
Packaging	PP screw vials

Product Manual	Technical Specification MSDS

Reference	1. Leonardi, R., Zhang, Y. M., Rock, C. O., & Jackowski, S. (2005). Coenzyme A: Back in action. Progress in Lipid Research, 44(2-3), 125-153. 2. Sibon, O. C. M., & Strauss, E. (2016). Coenzyme A: To make it or uptake it? Nature Reviews Molecular Cell Biology, 17(10), 606-607. 3. Spry, C., Kirk, K., & Saliba, K. J. (2008). Coenzyme A biosynthesis: An antimicrobial drug target. FEMS Microbiology Reviews, 32(1), 56-106. 4. Daugherty, M., Polanuyer, B., Farrell, M., Scholle, M., Lykidis, A., & de Crécy-Lagard, V. (2002). Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics. Journal of Biological Chemistry, 277(23), 21431-21439.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB21200017-1	A-17-10MG	10mg	$90.91		Add to Cart
BHB21200017-2	A-17-25MG	25mg	$93.75		Add to Cart
BHB21200017-3	A-17-50MG	50mg	$130.68		Add to Cart
BHB21200017-4	A-17-100MG	100mg	$188.07		Add to Cart

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