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Wuhan HealthCare Biotechnology Co., Ltd.
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Wuhan HealthCare Biotechnology Co., Ltd.
view supplier detailsCredit card payments now incur a 3% fee.
| Mfr.No. | KL-LY001 | ||
| Gene Name | BCL6 | ||
| Fluorophore | Orange/Green | ||
| Chromosome | 3 | ||
| Description |  BCL6 is a dual-color break probe that is a mixture of two probes directly labeled to 3q27.3-q28. The green fluorescent directly labeled probe hybridizes with the 3q27.3 proximal BCL6 gene, while the orange is red. The fluorescently labeled probe directly hybridizes to the distal end of the BCL6 gene of the 3q27.3-q28 distal group. |
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| Description | Hematological tumor | ||
| Clinical Significance | In diffuse large B-cell lymphoma, BCL6 gene can translocate with multiple genes, the incidence rate is 20%-40%; in follicular lymphoma, the incidence rate is 5-15%. Burkitt's lymphoma is morphologically suggestive of typical age, morphology, and immune characterization. If any of these three characteristics are not typical or have a history of follicular lymphoma with MYC gene breaks and BCL6 gene breaks, Gray area lymphoma between Burkitt/DLBCL should be diagnosed. This probe is used to detect whether the BCL6 gene is broken and translocated. BCL6 gene fragmentation is an independent indicator for evaluating survival rate and recovery rate. | ||
| Disease | Lymphoma | ||
| Location | 3q27.3-q28 | ||
| Size Specifications |  |
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