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Home / Primary Antibodies / Polyclonal Antibodies

GAB2 Antibody, HRP conjugated (CSB-PA892175LB01HU)

SKU : BHA10528301

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA892175LB01HU
Alternative Names	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (Growth factor receptor bound protein 2-associated protein 2) (pp100), GAB2, KIAA0571
Categories	Primary Antibodies
Clonality	polyclonal
Description	Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Host	Rabbit
Immunogen	Recombinant Human GRB2-associated-binding protein 2 protein (273-484AA)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Species	Homo Sapiens (Human)
Subcellular Location	Cytoplasm, Cell membrane

Antigen	GAB2
Uniprot	Q9UQC2
Database Links	HGNC:14458 OMIM:606203 KEGG:hsa:9846 STRING:9606.ENSP00000354952 UniGene:Hs.429434
Function	Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Pathway	Ras signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Osteoclast differentiation Phospholipase D signaling pathway Sphingolipid signaling pathway
Protein Families	GAB family
Research Area	Neuroscience

Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Format	Liquid
Purification	>95%, Protein G purified
Purity	>95%,Protein G purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Applications	ELISA
Description	ELISA
Tested Application	ELISA

Datasheet
ELISA Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10528301	CSB-PA892175LB01HU	50ug	$166		Add to Cart
BHA10528301	CSB-PA892175LB01HU	100ug	$299		Add to Cart

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