Synthesised peptide derived from human GSK3 alpha/beta
Purification
Purified by immunogen affinity chromatography.
Tested Application
WB, IHC
Uniprotkb
P49840 (UniProt, ExPASy)
Availability
Shipped within 5-10 working days.
Concentration
1 mg/ml
Target
GSK3 lpha/ beta
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Reactivity
Human, Mouse, Rat
Molecular Weight
51 kDa, 46 kDa
uniprot enrty name
GSK3A_HUMAN
Note
This product is for research use only.
Clonality
polyclonal
Buffer
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Recommended Dilution
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Description
GSK3 lpha/beta Antibody detects endogenous levels of total GSK3 lpha/beta. GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.