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Home / Primary Antibodies / IHC Antibodies

Recombinant SQSTM1/p62 Monoclonal Antibody

SKU : BHA10327212

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	E-AB-81512
Antigen	SQSTM1, p62
Background	Sequestosome 1 (SQSTM1/p62) is a multifunctional adaptor protein implicated in selective autophagy,cell signaling pathways,and tumorigenesis. p62 has been implicated in shuttling ubiquitinated and sometimes aggregated proteins for autophagic degradation. As a autophagy-specific substrate,p62 is degraded during the autophagic process,which makes intracellular level of p62 as a marker for autophagy flux. p62 is at the cross-roads of several signaling pathways including Ras/ Raf/ MAPK and NFkB and plays important role in cancer. p62 is a component of inclusion bodies/ protein aggregates found in human diseases,including Huntington's disease,Alzheimer's disease,Parkinson's disease in the brain,and nephropathic cystinosis in kidney (22074114,22860231,22714671). The molecular weight of p62 is predicted as 48/ 38 kDa,while western blot analyses using this antibody demonstrate the major band around 60-62 kDa in various tissues.
Categories	Primary Antibodies;Primary Antibodies///Monoclonal Antibodies
Clonality	Rabbit Monoclonal
Conjugate	Unconjugated
Host	Rabbit
Isotype	IgG
Molecular Weight	48kDa
Reactivity	Human
Synonyms	A170,DMRV,EBI 3 associated protein of 60 kDa,EBI 3 associated protein p60,EBI3 associated protein of 60 kDa,EBI3 associated protein p60,EBI3-associated protein of 60 kDa,EBIAP,FTDALS3,MGC127197,ORCA,OSF-6,Osi,OSIL,Oxidative stress induced like,p60,p62,p62B,Paget disease of bone 3,PDB 3,PDB3,Phosphotyrosine independent ligand for the Lck SH2 domain of 62 kDa,Phosphotyrosine independent ligand for the Lck SH2 domain p62,Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa,PKC-zeta-interacting protein,Protein kinase C-zeta-interacting protein,Sequestosome 1,Sequestosome-1,SQSTM 1,SQSTM,Sqstm1,STAP,STONE14,Ubiquitin binding protein p62,Ubiquitin-binding protein p62,ZIP 3,ZIP,ZIP3

Swissprot	Q13501
Accession Number	8878
Gene Id	8878
Clone No	R08-4H8

Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	300 ug/mL
Purification	Affinity Purified
Storage	Store at -20°C. Avoid freeze / thaw cycles.

Applications	WB
Dilution	WB 1:500-1:1000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10327212	E-AB-81512	50uL	$160		Add to Cart
BHA10327212	E-AB-81512	100uL	$260		Add to Cart

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