Rabbit Anti-Human LKB1 Polyclonal

Mfr.No.	SPC-1157, SPC-1157D, SPC-1157D-A390, SPC-1157D-A488, SPC-1157D-A594, SPC-1157D-BI, SPC-1157D-FITC
Immunogen Species	Human
Alternative Names	hLKB1 antibody, Liver kinase B1 antibody, LKB1 antibody, PJS antibody, Polarization related protein LKB1 antibody, Renal carcinoma antigen NY-REN-19 antibody, Serine/Threonine Kinase 11 antibody, Serine/threonine protein kinase STK11 antibody, Stk11 antibody, STK11_HUMAN antibody
Antigen	LKB1
Categories	Antibodies
Cellular Localization	Nucleus, Cytoplasm
Certificate Of Analysis	A 1:250 dilution of SPC-1157 was sufficient for detection of LKB1 in 10 ug of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Clonality	Polyclonal
Conjugate	Unconjugated, ATTO 390, ATTO 488, ATTO 594, Biotin, FITC
Description	Rabbit Anti-Human LKB1 Polyclonal
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Rabbit
Gross Weight (kg)	1.4
Immunogen	Synthetic peptide of human LKB1 (AA295-309), Homo Sapiens (Human)
Immunogen Region	Synthetic peptide of human LKB1 (AA295-309)
Launch Date	2016/08/29
Net Weight (g)	0.1
Reactivity	Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)
Species Reactivity Medium	Mouse, Human
Tissue Specificity	Ubiquitously expressed. Strongest expression in testis and fetal liver.

Swissprot	Q15831
Accession Number	NP_000446
Gene Id	6794
Target	LKB1
Research Area	Cell Cycle Inhibitors\| Cancer, Cancer, Cell Cycle, p53 Pathway, Cancer Metabolism, Cell Signaling, Metabolism, Energy Transfer Pathways

Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Dilutions	WB (1:250); optimal dilutions for assays should be determined by the user.
Purification	Peptide Affinity Purified
Purity	Ubiquitously expressed. Strongest expression in testis and fetal liver.
Scientific Background	LKB1 is a protein-serine/threonine kinase. Phosphorylates and activates AMP-activated kinase (AMPK), AMPK involved in stress responses, lipid and glucose metabolism. Its mutation pattern in human tumours is very characteristic of a tumour suppressor protein.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects 49 kDa.
Storage	-20ºC
Storage Buffer	PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	AM, WB
Description	WB ; AM
Dilution	WB (1:250); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11915642-1	SPC-1157D	Unconjugated	100 ul	$331	Add to Cart
BHA11915642-2	SPC-1157D-A390	ATTO 390	100 ul	$385	Add to Cart
BHA11915642-3	SPC-1157D-A488	ATTO 488	100 ul	$384	Add to Cart
BHA11915642-4	SPC-1157D-A594	ATTO 594	100 ul	$384	Add to Cart
BHA11915642-5	SPC-1157D-BI	Biotin	100 ul	$380	Add to Cart
BHA11915642-6	SPC-1157D-FITC	FITC	100 ul	$375	Add to Cart

LKB1 Antibody - SPC-1157