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Home / Proteins & Peptide

MIP-3 alpha/CCL20, Rat

SKU : BHP18500409

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Mfr.No.	IX03268, IX03268-25, IX03268-5
Reconstitution	Reconstituted in ddH2O or PBS at 100 ug/ml.
Description	Macrophage Inflammatory Protein-3 (MIP-3alpha), also known as chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC), is a small cytokine belonging to the CC chemokine family. It is strongly chemotactic for lymphocytes and weakly attracts neutrophils. MIP-3alphais implicated in the formation and function of mucosal lymphoid tissues via chemoattraction of lymphocytes and dendritic cells toward the epithelial cells surrounding these tissues. MIP-3alphais expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor.Recombinant rat MIP-3 alpha/CCL20 produced in HEK293 cells is a polypeptide chain containing 71 amino acids. A fully biologically active molecule, rrMIP-3 alpha/CCL20 has a molecular mass of 8.2 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
Formulation	Lyophilized after extensive dialysis against PBS.
Molecular Weight	8.2 kDa, observed by reducing SDS-PAGE.
Source	HEK 293
Host	Rat
Accession Number	P97884.1
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	The EC50 value of rat MIP-3 alpha/CCL20 on Ca2+ mobilization assay in CHO-K1/ G?15/rCCR6 cells (human G?15 and rat CCR6 stably expressed in CHO-K1 cells) is less than 0.6 ug/ml.

Synonyms	MIP-3 ?, Macrophage Inflammatory Protein-3?, CCL20, LARC, Exodus-1
Sequence	ASNFDCCLTY TKNVYHHARN FVGFTTQMAD EACDINAIIFHLKSKRSVCA DPKQIWVKRI LHLLSLRTKK M

Purity	98% as analyzed by SDS-PAGE.
Storage	Lyophilized recombinant Rat MIP-3 alpha/CCL20 remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, recombinant Rat MIP-3 alpha/CCL20 should be stable up to 1 week at 4°C or up to 2 months at -20°C.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500409-1	IX03268-25	25ug	$137		Add to Cart
BHP18500409-2	IX03268-5	5ug	$49		Add to Cart

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