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Home / Biochemicals / Small Molecules

Octanoyl Coenzyme A, Free acid

SKU : BHB21200068

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Mfr.No.	A-68, A-68-10MG, A-68-25MG, A-68-50MG
Description	Octanoyl coenzyme A (Octanoyl-CoA) is a medium-chain acyl-CoA derivative involved in crucial metabolic processes, particularly in lipid metabolism and energy production. It acts as a preferred substrate for ghrelin O-acyltransferase (GOAT), which catalyzes the octanoylation of the hunger-regulating peptide hormone ghrelin, a modification necessary for ghrelin's biological activity. Octanoyl-CoA participates in mitochondrial ?-oxidation, serving as a substrate for acyl-CoA dehydrogenases and other enzymes in the fatty acid degradation pathway. Its role is central in metabolic regulation, bridging nutrient sensing and energy homeostasis in various tissues (Yang et al., 2008; Hiltunen et al., 2005).
Appearance	White to slight yellow
Molecular Formula	C29H50N7O17P3S
Synonyms	Octanoyl-CoA, Capryloyl CoA, n-Octanoyl-CoA, Caprylyl coenzyme A
Shipping	Ambient temperature (styrofoam + ice gels)
Smiles	O=C(CCNC(C(C(C)(COP(O)(OP(O)(OCC(C(C1O)OP(O)(O)=O)OC1N(C2=NC=N3)C=NC2=C3N)=O)=O)C)O)=O)NCCSC(CCCCCCC)=O
Cas Number	1264-52-4
Molecular Weight	893.73 g/mol
Solubility	Soluble in water
Origin	Biosynthetic
Lead Time	6-8 weeks
Notes	Research Use Only

Purity	≥ 95.0%
Form	Lyophilized powder
Storage	-20°C in a cool and dry place
Stability	≥ 2 years
Packaging	PP screw vials

Product Manual	Technical Specification MSDS

Reference	1. Yang, J., Brown, M. S., Liang, G., Grishin, N. V., & Goldstein, J. L. (2008). Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. Cell, 132(3), 387-396. 2. Hiltunen, J. K., Filppula, S. A., Koivuranta, K. T., Qin, Y. M., & Palosaari, P. M. (2005). Mitochondrial fatty acid ?-oxidation in mammalian tissues. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1734(2), 101-128.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB21200068-1	A-68-10MG	10mg	$488.64		Add to Cart
BHB21200068-2	A-68-25MG	25mg	$846.59		Add to Cart
BHB21200068-3	A-68-50MG	50mg	$1238.64		Add to Cart

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