Phospho-5 Lipoxygenase (Ser272) Antibody

Mfr.No.	AF4399
Alternative Names	5 LO ; 5 LOX ; 5-lipoxygenase ; 5-LO ; 5-LOX ; 5LOX ; 5LPG ; ALOX 5 ; Alox5 ; Arachidonate 5 lipoxygenase ; Arachidonate 5-lipoxygenase ; arachidonic 5-lipoxygenase alpha-10 isoform ; arachidonic 5-lipoxygenase delta-10-13 isoform ; arachidonic 5-lipoxygenase delta-13 isoform ; arachidonic 5-lipoxygenase delta-p10 isoform ; Arachidonic acid 5 lipoxygenase ; Leukotriene A4 synthase ; LOG 5 ; LOG5 ; LOX5_HUMAN ; MGC163204 ;
Antigen	Phospho-5-Lipoxygenase (Ser272)
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Immunogen	A synthesized peptide derived from human 5-Lipoxygenase around the phosphorylation site of Ser272.
Molecular Weight	Observed Mol.Wt.: 78kDa. Predicted Mol.Wt.: 78kDa.
Reactivity	Human, Mouse, Rat
Specificity	Phospho-5-Lipoxygenase (Ser272) Antibody detects endogenous levels of 5-Lipoxygenase only when phosphorylated at Ser272.
Subcellular Location	Cytoplasm. Nucleus matrix. Nucleus membrane. Shuttles between cytoplasm and nucleus. Found exclusively in the nucleus, when phosphorylated on Ser-272. Calcium binding promotes translocation from the cytosol and the nuclear matrix to the nuclear envelope and membrane association.

Uniprot

P09917

Gene Id

240

Sequence

10 20 30 40 50
MPSYTVTVAT GSQWFAGTDD YIYLSLVGSA GCSEKHLLDK PFYNDFERGA
60 70 80 90 100
VDSYDVTVDE ELGEIQLVRI EKRKYWLNDD WYLKYITLKT PHGDYIEFPC
110 120 130 140 150
YRWITGDVEV VLRDGRAKLA RDDQIHILKQ HRRKELETRQ KQYRWMEWNP
160 170 180 190 200
GFPLSIDAKC HKDLPRDIQF DSEKGVDFVL NYSKAMENLF INRFMHMFQS
210 220 230 240 250
SWNDFADFEK IFVKISNTIS ERVMNHWQED LMFGYQFLNG CNPVLIRRCT
260 270 280 290 300
ELPEKLPVTT EMVECSLERQ LSLEQEVQQG NIFIVDFELL DGIDANKTDP
310 320 330 340 350
CTLQFLAAPI CLLYKNLANK IVPIAIQLNQ IPGDENPIFL PSDAKYDWLL
360 370 380 390 400
AKIWVRSSDF HVHQTITHLL RTHLVSEVFG IAMYRQLPAV HPIFKLLVAH
410 420 430 440 450
VRFTIAINTK AREQLICECG LFDKANATGG GGHVQMVQRA MKDLTYASLC
460 470 480 490 500
FPEAIKARGM ESKEDIPYYF YRDDGLLVWE AIRTFTAEVV DIYYEGDQVV
510 520 530 540 550
EEDPELQDFV NDVYVYGMRG RKSSGFPKSV KSREQLSEYL TVVIFTASAQ
560 570 580 590 600
HAAVNFGQYD WCSWIPNAPP TMRAPPPTAK GVVTIEQIVD TLPDRGRSCW
610 620 630 640 650
HLGAVWALSQ FQENELFLGM YPEEHFIEKP VKEAMARFRK NLEAIVSVIA
660 670
ERNKKKQLPY YYLSPDRIPN SVAI

Concentration	1mg/ml
Format	Liquid
Purification	The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Storage Condition	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Applications	ELISA, WB
Dilution	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Manual
MSDS
Sample Preparation For Western Blotting.
Western Blotting Handbook.

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SKU	Supplier No.	Size	Your price	Quantity
BHA12910908	AF4399	100ul	$350		Add to Cart
BHA12910908	AF4399	200ul	$450		Add to Cart