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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Annexin A3/ANXA3 Antibody Picoband®

SKU : BHA21002130

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Mfr.No.	A04796, A04796-10ug, A04796-Biotin, A04796-Cy3, A04796-Dylight488, A04796-Dylight550, A04796-Dylight594, A04796-FITC, A04796-HRP, A04796-APC, A04796-PE, A04796-iFluor647, A04796-carrier-free
Alternative Names	annexin A3
Background	Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Annexin A3/ANXA3 Antibody Picoband® catalog # A04796. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Inhibitor of phospholipase A2, also possesses anti-coagulant properties. Also cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate.
Host	Rabbit
Immunogen Region	E.coli-derived human Annexin A3/ANXA3 recombinant protein (Position: D23-D323).
Isotype	Rabbit IgG
Molecular Weight	36 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Annexin A3; 35-alpha calcimedin; Annexin III; Annexin-3; Inositol 1,2-cyclic phosphate 2-phosphohydrolase; Lipocortin III; Placental anticoagulant protein III;PAP-III; ANXA3; ANX3
Tissue Specificity	Widely expressed. Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine. Weakly expressed in small intestine.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P12429
Gene Id	306
Gene Name	ANXA3
Subcellular Location	Cytosol. Extracellular exosome. Plasma membrane. Axon. Cytoplasm. Dendrite. Membrane. Neuronal cell body. Phagocytic vesicle membrane. Specific granule.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, IHC, WB
Description	Western blot, 0.1-0.5ug/ml<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. Bianchi C, et al. Primary cell cultures from human renal cortex and renal-cell carcinoma evidence a differential expression of two spliced isoforms of Annexin A3. Am J Pathol, 2010 Apr.<br /><br />2. Jung EJ, et al. Decreased annexin A3 expression correlates with tumor progression in papillary thyroid cancer. Proteomics Clin Appl, 2010 May.<br /><br />3. Yan X, et al. Increased expression of annexin A3 is a mechanism of platinum resistance in ovarian cancer. Cancer Res, 2010 Feb 15.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002130-1	A04796	-	100 ug	$370		Add to Cart
BHA21002130-2	A04796-10ug	Sample	10 ug	$99		Add to Cart
BHA21002130-3	A04796-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002130-4	A04796-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002130-5	A04796-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002130-6	A04796-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002130-7	A04796-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002130-8	A04796-FITC	FITC	100 ug	$570		Add to Cart
BHA21002130-9	A04796-HRP	HRP	100 ug	$570		Add to Cart
BHA21002130-10	A04796-APC	APC	100 ug	$670		Add to Cart
BHA21002130-11	A04796-PE	PE	100 ug	$670		Add to Cart
BHA21002130-12	A04796-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002130-13	A04796-carrier-free	carrier-free	100 ug	$370		Add to Cart

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