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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Carbonic Anhydrase III/CA3 Antibody Picoband®

SKU : BHA21000954

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Mfr.No.	PB10049, PB10049-10ug, PB10049-Biotin, PB10049-Cy3, PB10049-Dylight488, PB10049-Dylight550, PB10049-Dylight594, PB10049-FITC, PB10049-HRP, PB10049-APC, PB10049-PE, PB10049-iFluor647, PB10049-carrier-free
Alternative Names	Carbonic anhydrase 3
Background	Carbonic anhydrase III (CA3) is an enzyme that in humans is encoded by the CA3 gene. CA3 is a member of a multigene family (at least six separate genes are known) that encode carbonic anhydrase isozymes. The gene spans 10.3 kb and contains seven exons and six introns. Using a cDNA clone of the CA3 gene in the study of human-rodent hybrids, the gene was mapped to chromosome 8 which carries a cluster of CA genes. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Carbonic Anhydrase III/CA3 Antibody Picoband® catalog # PB10049. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Reversible hydration of carbon dioxide.
Host	Rabbit
Immunogen Region	E. coli-derived human CA3 recombinant protein (Position: D14-E235). Human CA3 shares 92.3% and 91.4% amino acid (aa) sequence identity with mouse and rat CA3, respectively.
Isotype	Rabbit IgG
Molecular Weight	29 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Carbonic anhydrase 3;4.2.1.1;Carbonate dehydratase III;Carbonic anhydrase III;CA-III;CA3;
Tissue Specificity	Muscle specific.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P07451
Gene Id	761
Gene Name	CA3
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat Western blot, 0.1-0.5ug/ml, Mouse, Rat, Human

Reference	1. Edwards, Y. H., Lloyd, J. C., Parkar, M., Povey, S.The gene for human muscle specific carbonic anhydrase (CAIII) is assigned to chromosome 8.Ann. Hum. Genet. 50: 41-47, 1986. 2. Heath, R., Carter, N. D., Jeffery, S., Edwards, R. J., Watts, D. C., Watts, R. L.Evaluation of carrier detection of Duchenne muscular dystrophy using carbonic anhydrase III and creatine kinase.Am. J. Med. Genet. 21: 291-296, 1985. 3. Wade, R., Gunning, P., Eddy, R., Shows, T., Kedes, L.Nucleotide sequence, tissue-specific expression, and chromosome location of human carbonic anhydrase III: the human CAIII gene is located on the same chromosome as the closely linked CAI and CAII genes.Proc. Nat. Acad. Sci. 83: 9571-9575, 1986.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000954-1	PB10049	100 ug	-	$370		Add to Cart
BHA21000954-2	PB10049-10ug	10 ug	Sample	$99		Add to Cart
BHA21000954-3	PB10049-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000954-4	PB10049-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000954-5	PB10049-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000954-6	PB10049-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000954-7	PB10049-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000954-8	PB10049-FITC	100 ug	FITC	$570		Add to Cart
BHA21000954-9	PB10049-HRP	100 ug	HRP	$570		Add to Cart
BHA21000954-10	PB10049-APC	100 ug	APC	$670		Add to Cart
BHA21000954-11	PB10049-PE	100 ug	PE	$670		Add to Cart
BHA21000954-12	PB10049-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000954-13	PB10049-carrier-free	100 ug	carrier-free	$370		Add to Cart

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