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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Connexin 45/GJA7/GJC1 Antibody Picoband®

SKU : BHA21007393

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Mfr.No.	PA2206, PA2206-10ug, PA2206-Biotin, PA2206-Cy3, PA2206-Dylight488, PA2206-Dylight550, PA2206-Dylight594, PA2206-FITC, PA2206-HRP, PA2206-APC, PA2206-PE, PA2206-iFluor647, PA2206-carrier-free
Alternative Names	Gap junction gamma-1 protein
Background	Gap junction gamma-1 protein (GJC1), also known as gap junction alpha-7 protein (GJA7) or connexin 45 (Cx45), is a protein that in humans is encoded by the GJC1 gene. The International Radiation Hybrid Mapping Consortium mapped the GJA7 gene to chromosome 17q21.31. This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Connexin 45/GJA7/GJC1 Antibody catalog # PA2206. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human Connexin 45, different from the related mouse and rat sequences by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	53 kDa
Reactivity	Rat, Mouse, Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Gap junction gamma-1 protein;Connexin-45;Cx45;Gap junction alpha-7 protein;GJC1;GJA7;
Tissue Specificity	Brain, liver, placenta, lymphocytes and erythrocytes.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P36383
Gene Name	GJC1
Sequence	Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O- methyltransferase family.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Western blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br>

Reference	1. Kaba, R. A., Coppen, S. R., Dupont, E., Skepper, J. N., Elneil, S., Haw, M. P., Pepper, J. R., Yacoub, M. H., Rothery, S., Severs, N. J. Comparison of connexin 43, 40 and 45 expression patterns in the developing human and mouse hearts. Cell Commun. Adhesion 8: 339-343, 2001.<br /><br />2. Tsai, M.-Y., Lan, K.-C., Huang, K.-E., Huang, F.-J., Kung, F.-T., Chang, S.-Y. Significance of mRNA levels of connexin37, connexin43, and connexin45 in luteinized granulosa cells of controlled hyperstimulated follicles. Fertil. Steril. 80: 1437-1443, 2003. <br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007393-1	PA2206	-	100 ug	$370		Add to Cart
BHA21007393-2	PA2206-10ug	Sample	10 ug	$99		Add to Cart
BHA21007393-3	PA2206-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007393-4	PA2206-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007393-5	PA2206-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007393-6	PA2206-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007393-7	PA2206-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007393-8	PA2206-FITC	FITC	100 ug	$570		Add to Cart
BHA21007393-9	PA2206-HRP	HRP	100 ug	$570		Add to Cart
BHA21007393-10	PA2206-APC	APC	100 ug	$670		Add to Cart
BHA21007393-11	PA2206-PE	PE	100 ug	$670		Add to Cart
BHA21007393-12	PA2206-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007393-13	PA2206-carrier-free	carrier-free	100 ug	$370		Add to Cart

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