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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PPP1R15B Antibody Picoband®

SKU : BHA21005278

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Mfr.No.	A10225-1, A10225-1-10ug, A10225-1-Biotin, A10225-1-Cy3, A10225-1-Dylight488, A10225-1-Dylight550, A10225-1-Dylight594, A10225-1-FITC, A10225-1-HRP, A10225-1-APC, A10225-1-PE, A10225-1-iFluor647, A10225-1-carrier-free
Alternative Names	Protein NDRG3
Background	PPP1R15B(Protein phosphatase 1, regulatory subunit 15b), also called CREP, promotes dephosphorylation of the transcription initiation factor EIF2-alpha through recruitment of protein phosphatase-1(PP1) catalytic subunits. The PPP1R15B gene is mapped to chromosome 1q32.1 based on an alignment of thePPP1R15B sequence by Hartz(2010). Harding et al.(2009) obtained Ppp1r15b -/- mice at a mendelian ratio. However, Ppp1r15b -/- newborns were half the size of their wildtype littermates, were notably pale, and failed to nurse, and none survived the first day of postnatal life. Ppp1r15b -/- embryos that were also homozygous for an Eif2-alpha mutation that prevented Eif2-alpha phosphorylation were normalized, including elevated birth size and restored red blood cell count, compared with Ppp1r15b -/- embryos with wildtype Eif2-alpha.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-PPP1R15B Antibody Picoband® catalog # A10225-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
Host	Rabbit
Immunogen Region	E.coli-derived human PPP1R15B recombinant protein (Position: Q211-D657).
Isotype	Rabbit IgG
Molecular Weight	110 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Protein NDRG3;N-myc downstream-regulated gene 3 protein;NDRG3;
Tissue Specificity	Ubiquitous. Highly expressed in brain. .
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q5SWA1
Gene Id	84919
Gene Name	PPP1R15B
Subcellular Location	Membrane ; Single-pass type I membrane protein .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, ICC, IF, Flow Cytometry, ELISA
Description	Western blot, 0.25-0.5 ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Harding, H. P., Zhang, Y., Scheuner, D., Chen, J.-J., Kaufman, R. J., Ron, D. Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2-alpha) dephosphorylation in mammalian development. Proc. Nat. Acad. Sci. 106: 1832-1837, 2009.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005278-1	A10225-1	-	100 ug	$370		Add to Cart
BHA21005278-2	A10225-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21005278-3	A10225-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005278-4	A10225-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005278-5	A10225-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005278-6	A10225-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005278-7	A10225-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005278-8	A10225-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21005278-9	A10225-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21005278-10	A10225-1-APC	APC	100 ug	$670		Add to Cart
BHA21005278-11	A10225-1-PE	PE	100 ug	$670		Add to Cart
BHA21005278-12	A10225-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005278-13	A10225-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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