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Home / Primary Antibodies / Polyclonal Antibodies

Anti-SGLT1/SLC5A1 Antibody Picoband®

SKU : BHA21007420

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Mfr.No.	PA2244, PA2244-10ug, PA2244-Biotin, PA2244-Cy3, PA2244-Dylight488, PA2244-Dylight550, PA2244-Dylight594, PA2244-FITC, PA2244-HRP, PA2244-APC, PA2244-PE, PA2244-iFluor647, PA2244-carrier-free
Alternative Names	Sodium/glucose cotransporter 1
Background	Sodium/glucose cotransporter 1 (SLC5A1), also known as NAGT or SGLT1 is a protein that in humans is encoded by the SLC5A1 gene. This gene is mapped to 22q12.3. This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-SGLT1/SLC5A1 Antibody catalog # PA2244. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Actively transports glucose into cells by Na (+) cotransport with a Na (+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capa
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of mouse SGLT1, different from the related rat sequence by one amino acid, and from the related human sequence by two amino acids.
Isotype	Rabbit IgG
Molecular Weight	73 kDa
Reactivity	Rat, Mouse, Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Sodium/glucose cotransporter 1;Na (+)/glucose cotransporter 1;High affinity sodium-glucose cotransporter;Solute carrier family 5 member 1;SLC5A1;NAGT, SGLT1;
Tissue Specificity	Expressed mainly in intestine and kidney.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P13866
Gene Name	SLC5A1
Sequence	Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Subcellular Location	Membrane; Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Western blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br>

Reference	1. Margolskee, R. F., Dyer, J., Kokrashvili, Z., Salmon, K. S. H., Ilegems, E., Daly, K., Maillet, E. L., Ninomiya, Y., Mosinger, B., Shirazi-Beechey, S. P. T1R3 and gustducin in gut sense sugars to regulate expression of Na(+)-glucose cotransporter 1. Proc. Nat. Acad. Sci. 104: 15075-15080, 2007.<br /><br />2. Turk, E, Wright, E. M. Membrane topology motifs in the SGLT cotransporter family. J. Membr. Biol. 159: 1-20, 1997.<br /><br />3. Wright, E. M., Turk, E., Zabel, B., Mundlos, S., Dyer, J. Molecular genetics of intestinal glucose transport. J. Clin. Invest. 88: 1435-1440, 1991.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007420-1	PA2244	-	100 ug	$370		Add to Cart
BHA21007420-2	PA2244-10ug	Sample	10 ug	$99		Add to Cart
BHA21007420-3	PA2244-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007420-4	PA2244-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007420-5	PA2244-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007420-6	PA2244-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007420-7	PA2244-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007420-8	PA2244-FITC	FITC	100 ug	$570		Add to Cart
BHA21007420-9	PA2244-HRP	HRP	100 ug	$570		Add to Cart
BHA21007420-10	PA2244-APC	APC	100 ug	$670		Add to Cart
BHA21007420-11	PA2244-PE	PE	100 ug	$670		Add to Cart
BHA21007420-12	PA2244-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007420-13	PA2244-carrier-free	carrier-free	100 ug	$370		Add to Cart

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