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Home / Primary Antibodies / Polyclonal Antibodies

PKC ? (phospho Tyr52) Rabbit pAb

SKU : BHA15205776

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ELK Biotechnology

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Mfr.No.	ES6775
Antigen	PKC ? (phospho Tyr52)
Background	Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (?, ?I, ?II and ?) and novel (n) PKC isoforms (?, ?, ?, ?, ?, ?/?, µ and ?). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC ? and ? are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.
Clonality	Polyclonal
Conjugate	Unconjugate
Host	Rabbit
Immunogen	Synthesized peptide derived from human PKC ? around the phosphorylation site of Y52.
Isotype	IgG
Reactivity	Human, Mouse, Rat

Gene Id	5580

Concentration	1mg/ml
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, IF, ELISA

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA15205776	ES6775	50µl	$148		Add to Cart
BHA15205776	ES6775	100µl	$248		Add to Cart

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