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Home / Primary Antibodies / Polyclonal Antibodies

TRAF5 Antibody (CSB-PA024153GA01HU)

BHA10548932
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Tel
+1 866.986.9598
Email
[email protected]
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Antigen TRAF5
Target Details The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Alternate transcriptional splice variants have been characterized.
Uniprot O00463
Database Links

HGNC:12035

OMIM:602356

KEGG:hsa:7188

STRING:9606.ENSP00000261464

UniGene:Hs.523930
Function Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.
Pathway NF-kappa B signaling pathway TNF signaling pathway Necroptosis IL-17 signaling pathway NOD-like receptor signaling pathway
Protein Families TNF receptor-associated factor family, A subfamily
Tissue Specificity Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood.
Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20℃, Avoid freeze / thaw cycles.
Format Liquid
Purification Antigen Affinity Purified
Purity Antigen Affinity Purified
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Applications ELISA, WB, IHC
Description ELISA ; WB ; IHC, WB ; ELISA ; IHC
Tested Application ELISA,WB,IHC
Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
SKU Supplier No. Size Your price Quantity
BHA10548932 CSB-PA024153GA01HU 100ul $600
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